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      community My RU58841 Progress / Hair loss journey

      in Progress Pictures  72 upvotes 3 years ago
      A user shared their experience with hair loss treatments, including RU58841, ketoconazole shampoo, caffeine shampoo, and topical finasteride. They found RU58841 effective for diffuse thinning but experienced severe hair loss after stopping it; topical finasteride worked well for a receding hairline but caused side effects. They also use a charcoal shampoo and practice scalp massages.

      community Well… I Did It. Estrogen Saved My Hairline

      in Transgender  725 upvotes 4 months ago
      OP transitioned and used Spironolactone, Estradiol Valerate, Minoxidil, and dermarolling, resulting in significant hair regrowth. They advise this method may not be suitable for cis men.
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      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 5 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Gyno & testoterone level

      in Finasteride  282 upvotes 7 months ago
      Switching from finasteride to dutasteride and back to finasteride led to gynecomastia and fatigue, likely due to hormonal imbalances. Suggested treatments include Tamoxifen, Raloxifene, or low-dose Anastrozole, with a recommendation to test testosterone and estradiol levels.

      community Here are the results from my journey! I used saw palmetto tablets instead of Finasteride(I was afraid of using it), 5% Minoxidil spray and Derma Pen once a week 1.5mm.

      in Progress Pictures  306 upvotes 1 year ago
      The user shared their positive hair regrowth experience using saw palmetto tablets, 5% minoxidil spray, and a Derma Pen. The conversation debates the effectiveness of saw palmetto versus finasteride, with some advocating for natural treatments and others emphasizing the proven results of finasteride and minoxidil, often in combination with microneedling.

      community My Pyrilutamide Experience so far

      in Update  78 upvotes 2 years ago
      A user's experience with Pyrilutamide for hair loss, which has been successful in reversing receding hairline when part of their stack with other treatments such as Dutasteride, Minoxidil, and Ketoconazole shampoo.

      community 2 year progress on fin and minox

      in Progress Pictures  1150 upvotes 4 years ago
      A user's 2-year experience with Minoxidil and Finasteride as a treatment for hair loss, including the costs involved and potential side effects. Other users shared their experiences and asked questions about their own use of these treatments.
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      community Does finasteride decrease free testosterone?

      in Research/Science  186 upvotes 1 month ago
      Finasteride may decrease free testosterone by increasing SHBG, potentially causing side effects like reduced libido and hormonal changes. Some find it effective for hair loss, while others experience negative effects.

      community Why is it so hard to select one

      in Satire  640 upvotes 2 months ago
      Choosing hair loss treatments is challenging due to concerns about side effects from finasteride and minoxidil. Users suggest starting with topical treatments and gradually increasing dosage, while some recommend oral finasteride for its effectiveness despite potential side effects.

      community The Worst Hair Loss Condition You (MAY) have: LPP

      in Research/Science  43 upvotes 5 months ago
      Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

      community Proof that finasteride messes with neurosteroids

      in Research/Science  230 upvotes 6 months ago
      Finasteride can impact neurosteroids, potentially causing depression and other side effects in some users. Despite these concerns, many continue using it for hair loss, with some switching to topical applications to mitigate side effects.

      community Just popped my first fin, excited as hell!

      in Finasteride/Dutasteride  154 upvotes 8 months ago
      A user shared their excitement about starting finasteride for hair loss after trying various ineffective methods. Other users discussed their experiences with finasteride, including shedding phases and side effects, with one mentioning using topical finasteride and minoxidil.

      community Why is it that low testosterone causes hair loss as well? How can I be balding?

      in Chat  158 upvotes 9 months ago
      The conversation discusses the confusion over low testosterone potentially causing hair loss, with users sharing personal experiences and knowledge about hair loss treatments like Finasteride. Some users suggest that hair follicle sensitivity to DHT, not testosterone levels, is the key factor in balding, and others discuss the side effects of hair loss medications.

      community Saying creatine causes loss on fin/dut makes no sense and this is why

      in Finasteride/Dutasteride  42 upvotes 1 year ago
      The conversation discusses whether creatine causes hair loss for those using finasteride or dutasteride, with some suggesting creatine might increase DHT or upregulate androgen receptors, potentially leading to hair loss. Others argue the evidence is not conclusive, citing limited studies and personal anecdotes, with some avoiding creatine as a precaution.

      community Topical finasteride has affected my hormones

      in Finasteride/Dutasteride  27 upvotes 1 year ago
      A 21-year-old experienced hormone changes after using self-made topical finasteride for hair loss, including a 20% decrease in DHT, a 47% increase in testosterone, and a 39% increase in estradiol. The user previously used minoxidil and microneedling but is now seeking ways to balance hormones, possibly through supplements or dosage adjustments.

      community Does whey protein and creatine aggravate hair loss?

      in Research/Science  82 upvotes 1 year ago
      The conversation discusses whether whey protein and creatine worsen hair loss. Some users report hair loss with creatine use, while others do not; opinions on whey protein's effects are mixed. Treatments mentioned include PRP, minoxidil, and finasteride.

      community Testosterone and hair loss seeming irrelevance

      in Research/Science  81 upvotes 1 year ago
      The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.

      community Why I Will be Accepting Baldness

      in Chat  204 upvotes 1 year ago
      User decides to accept baldness due to mental health issues with finasteride. Others suggest considering hair systems, topical finasteride, or RU58841 as alternatives.

      community Does Ashwagandha cause hair loss?

      in Chat  24 upvotes 1 year ago
      User asks if Ashwagandha causes hair loss while using Finasteride and Minoxidil. Replies suggest Ashwagandha may increase shedding, but raising testosterone within normal levels likely won't significantly affect hair loss.