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GlossaryProgenitor Cells

cells that can differentiate into specific cell types but are more limited than stem cells

Progenitor cells are a type of cell that has the capacity to differentiate into a specific type of cell but is more limited than a stem cell. Unlike stem cells, which can divide indefinitely and become any cell type, progenitor cells are already on the path to becoming a particular kind of cell and can only divide a limited number of times. They play a crucial role in tissue development and repair, including in the regeneration of hair follicles.

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community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

in Research/Science 92 upvotes 2 years ago

The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.

community The Real Cause Of Androgenetic Alopecia

in Research/Science 667 upvotes 2 months ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community Hair theory Scar tissue and Verteporfin

in Chat 26 upvotes 6 months ago

A user suggests that deeper microneedling with Verteporfin injections might help regrow hair in areas with scar tissue, alongside a DHT blocker. Another user explains that hair loss might be due to reduced Wnt/β-Catenin signaling and suggests that treatments like Minoxidil, Finasteride, and microneedling could potentially reverse it.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Solving Hair Loss with Research at MIT

in Research/Science 594 upvotes 2 months ago

Hair loss treatments like minoxidil, finasteride, TDM-105795, and PP405. MIT is hosting a hackathon to find innovative hair loss solutions.

community Minoxidil can prevent hair follicle miniaturization!?

in Minoxidil 6 upvotes 3 years ago

Minoxidil can prevent hair follicle miniaturization, not just stimulate hair growth. Finasteride and dutasteride don't work for everyone, suggesting DHT may not be the sole cause of hair loss; hair loss could be due to multiple factors, including autoimmune conditions.

community Stem Cells May Get Rid Of Balding FOREVER!

in Technology 7 upvotes 5 months ago

Stem cell therapy shows promise in treating hair loss by mimicking DHT-resistant cells from the back of the head. Traditional treatments like finasteride are also discussed, but stem cells could potentially offer a more permanent solution.

community STEM CELL TREATMENT FOR HAIR LOSS at home

in Treatment 6 upvotes 3 years ago

User considers trying AAPE for hair restoration, costing $700 for 6 months. Others discuss its potential effectiveness and mention a study with promising results.

community Mesenchymal Stem Cell Therapy (Exosome) Before & After

in Treatment 2 upvotes 8 months ago

A user's father experienced hair regrowth and other health improvements after two IV exosome treatments. The user also had four rounds of exosome therapy, noting significant hair regrowth and relief from headaches, but no change in gray hair.

community Seeking Advice: Stem Cell Therapy vs. PRP for Hair Loss

in Treatment 2 upvotes 7 months ago

The conversation is about someone seeking advice on choosing between stem cell therapy and PRP for treating hair loss, asking for personal results, side effects, overall satisfaction, and recommendations from others.

community PP405 - hair stem cell stimulation

in Research/Science 51 upvotes 9 months ago

PP405, a topical LDH inhibitor, has shown to stimulate hair follicle stem cell proliferation in humans with moderate hair loss. They are advancing to more detailed trials this year.

community This guy claims stem cells fixed his balding

in Is this regrowth? 301 upvotes 1 year ago

A man who claimed to have regrown his hair using stem cell treatment, sparking a debate about its effectiveness and cost. Some users suggested he might be using other treatments or substances, while others shared their own experiences with stem cell therapy for hair loss.

community redensyl - follicle stem cell activator any experiences?

in Question 9 upvotes 7 years ago

A Swiss product called Redensyl, which is supposed to target hair follicle stem cells and has recently been marketed in Europe. The post inquires if anyone has had any experience with the product.

community 1.5 Year Hair Restoration Journey - Stem Cells, PRP, Minoxidil, Topical Finasteride

in Progress Pictures 27 upvotes 10 months ago

A user shared their 1.5-year hair restoration journey, successfully using mesenchymal stem cell therapy, Platelet Rich Plasma (PRP) injections, and a topical compound of finasteride and minoxidil, avoiding a hair transplant and oral finasteride. They experienced significant hair regrowth, particularly crediting the stem cell therapy for quick initial results.

community Microneedling and aloe vera to recruit stem cells.

in Chat 11 upvotes 10 months ago

Microneedling combined with aloe vera may stimulate dormant stem cells in hair loss areas. Minoxidil is also suggested for better results.

community Best Microneedle Lengths To Stimulate Stem Cells

in Microneedling 18 upvotes 1 year ago

Microneedling with needle lengths of 1.5mm to 2.5mm to stimulate hair follicle stem cells for potential hair growth. Using needles longer than 2.5mm is not recommended due to risk of puncturing veins in the scalp. A dermastamp is suggested over a roller.

community I am not losing my hair (yet) and do not think I will soon, but I am a pre medicine major who has an obsession over stem cells and want to share something with you all. Your future is brighter than you think.

19 upvotes 7 years ago

User hoodoomoovoo discusses their interest in stem cell research and its potential for hair loss treatment. They share links to studies and mention ongoing trials, expressing optimism for a future solution to hair loss.

community Anyone ever heard of this type of product uses stem cells ?

in Product 2 upvotes 8 months ago

The conversation is about a hair loss product that claims to use stem cells and ingredients like Capixyl, Redensyl, and Baicapil, with the user asking if anyone has looked into it. No specific treatments were discussed.

community Non-Fin Super Regimen (Fluridil, Min, Stem, Niz, Viviscal, Broccoli Sprouts, Derma)

in Product 14 upvotes 3 years ago

Hair loss treatments discussed include Fluridil, Minoxidil, Stem, Niz, Viviscal, Broccoli Sprouts, and Derma. One user claims most treatments are ineffective, while another supports Eucapil.

community Does PRP, Exosome therapy, peptides, Stem Cell - any of 'em work?

in Research/Science 2 upvotes 1 year ago

The conversation discusses hair loss and queries the effectiveness of treatments like PRP, Exosome therapy, peptides, and Stem Cell therapy. Specific treatments like Minoxidil, finasteride, and RU58841 are also mentioned.

community Minoxidil and skin aging worry – which prevention methods (platelet rich plasma, microneedlig, mesotherapy, stem cells, co2, ultherapy, …)

in Chat 4 upvotes 2 years ago

User started minoxidil, noticed forehead lines and dark circles, and asked for non-invasive skin aging prevention methods. Another user suggested using tretinoin and hyaluronic acid for long-term benefits.

community If the main mechanism of microneedling is an increase in bloodflow to the scalp, shouldn't we be pursuing other actions which increase bloodflow? Sauna, cold showers, high dosage fish oil, hard cardio, heme-iron(red meats), HAND STANDS, foods high in NO (arugula), ginger, increased water consumption

in Question 17 upvotes 5 years ago

Microneedling stimulates hair growth through stem cell activation during wound healing, not just increased blood flow. Other methods like showers or supplements don't replicate this effect.

community Likelihood of a new treatment?

in Chat 6 upvotes 2 weeks ago

New hair loss treatments like stem cells, hair cloning, and gt20029 are unlikely to be available in the next 5-10 years, with some trials possibly starting by 2026. Current treatments like Minoxidil and Finasteride have been used for decades, and new developments depend on funding and successful trials.

community Fun thought experiment about halting hair loss permamently

in Research/Science 58 upvotes 7 months ago

A user proposed genetically engineering scalp stem cells to stop androgen receptors from causing hair loss. Others discussed the feasibility, existing research, and potential issues with this approach, including targeting the correct cells and unintended effects.

community How Does Exosome Therapy Work for Hair Loss?

in Research/Science 5 upvotes 1 year ago

Exosome hair therapy involves injecting stem cell-derived exosomes into the scalp to boost hair follicle regeneration and repair. Exosomes, which are not stem cells but products of them, contain bioactive chemicals and specific growth factors that promote new blood vessel formation, increase cell proliferation, reduce inflammation, and improve tissue repair, all crucial for hair health.

community Any promising new research or techniques for hair loss treatment and hair transplants?

in Research/Science 6 upvotes 4 days ago

The conversation discusses new hair loss treatments like stem cell therapy, exosome treatments, and DHI, with mentions of GT20029, Amp303, and Plated PRP Serum as promising options. It also notes the use of dutasteride, topical finasteride, and minoxidil, but the focus is on non-hormonal innovations.

community Stemson Therapeutics Announces Technological Breakthrough in new Hair Growth

in Research/Science 61 upvotes 10 months ago

Stemson Therapeutics announced a breakthrough in hair growth technology using stem cells. Users discussed the potential high cost and skepticism about the treatment's accessibility.

community Has anyone tried either of the new exosome based hair loss treatments (ExoFlo and XoFlo)? If so what were your results like?

in Treatment 6 upvotes 2 years ago

Hair loss treatments ExoFlo and XoFlo use exosomes from stem cells to stimulate hair growth. The user seeks feedback on results from those who tried these treatments.

community Does microneedling regrow hair on dormant bald regions which have been bald for many years?

in Microneedling 6 upvotes 4 years ago

Microneedling may help regrow hair in dormant bald regions by stimulating stem cell transfer. Users discuss its effectiveness and how collagen might aid in the process.

community The Korean began to suspect something. But they understood the mechanism to some extent. ( Cold shock therapy promotes hair growth in association with upregulation of cold-inducible RNA-binding protein and vascular endothelial growth factor)

in Research 86 upvotes 3 weeks ago

Cold shock therapy may promote hair growth by stimulating follicular muscles and affecting stem cells. The exact mechanisms and full range of elements involved are not yet fully understood.