TWIST-1 gene's role in hair loss and potential as a treatment target. Inhibiting TWIST-1 may prolong hair growth and reduce hair follicle sensitivity to DHT.
Topical Dutasteride may halt hair loss and effectively treat androgenic alopecia. Combining low-dose oral Dutasteride with topical application could maximize regrowth and minimize side effects.
The conversation discusses CRISPR-on & CRISPR-off as a potential cure for baldness, contrasting it with hair cloning and other treatments like Minoxidil, finasteride, and RU58841. It also mentions the potential of mRNA for gene expression control and the prioritization of gene editing for severe genetic conditions.
A 26-year-old male started minoxidil treatment for male-pattern baldness and saw significant regrowth in three months. He is considering finasteride but is hesitant due to potential side effects.
The conversation discusses hair loss treatments, with users mentioning dutasteride (Dut) as effective and wishing for more accessible dosages. They also debate the components of the "big 3" treatments, which now include Dut, RU58841, and oral minoxidil, with finasteride and minoxidil being consistently mentioned.
The conversation is about a hair loss product that claims to use stemcells and ingredients like Capixyl, Redensyl, and Baicapil, with the user asking if anyone has looked into it. No specific treatments were discussed.
Hair loss treatments discussed include Fluridil, Minoxidil, Stem, Niz, Viviscal, Broccoli Sprouts, and Derma. One user claims most treatments are ineffective, while another supports Eucapil.
User started minoxidil, noticed forehead lines and dark circles, and asked for non-invasive skin aging prevention methods. Another user suggested using tretinoin and hyaluronic acid for long-term benefits.
A user proposed genetically engineering scalp stemcells to stop androgen receptors from causing hair loss. Others discussed the feasibility, existing research, and potential issues with this approach, including targeting the correct cells and unintended effects.
Stemson Therapeutics announced a breakthrough in hair growth technology using stemcells. Users discussed the potential high cost and skepticism about the treatment's accessibility.
Hair loss treatments ExoFlo and XoFlo use exosomes from stemcells to stimulate hair growth. The user seeks feedback on results from those who tried these treatments.
A video suggests 0.6mm microneedling is more effective for hair regrowth than 1.2mm, as it causes less trauma to stemcells. People commonly believe 1.5mm is best, but this may vary based on individual factors.
The conversation discusses GT20029, a drug in Phase II trials that targets androgen receptors with minimal systemic effects, and TDM-105795, a growth stimulant with a different mechanism than minoxidil that may revive papilla stemcells. Both are potential new treatments for hair loss.
Barcelona goalkeeper Ter Stegen's hair growth regimen, which is believed to include a transplant and other treatments such as finasteride, minoxidil, PRP injections, DUT injections, and possibly stemcells.
The user experienced side effects commonly attributed to Finasteride without ever taking the drug, suggesting these issues may stem from other life factors. They advise considering other potential causes before blaming Finasteride for such side effects.
User shared 1.5-year progress using 1mg finasteride, 15% minoxidil daily, and derma rolling weekly. Experienced initial shedding but achieved significant hair regrowth and improvement.
The conversation is about someone's hair transplant progress after 9 months on finasteride and oral minoxidil, considering switching to dutasteride. Specific treatments mentioned include hair transplant, finasteride, oral minoxidil, and a potential switch to dutasteride.
The user is using a combination of RU58841, Stemoxydine, RevivHair Serum, hair growth oil, topical Minoxidil, Alfatradiol, oral Minoxidil, and Finasteride to treat hair loss. They report no side effects from oral Minoxidil and Finasteride after 7 months of use.
The conversation discusses a claim that peppermint oil is more effective than minoxidil for hair loss, with one user mentioning using a mix of peppermint and rosemary oils as a treatment. Some users are skeptical, while others show interest in the potential of peppermint oil.
Hair cloning trials by Stempsen Therapeutics and Hairclone have no updates, and it may take at least 15 years for hair cloning to be available. The conversation also mentions treatments like Minoxidil, finasteride, and RU58841.
The conversation is about using stemoxydine in addition to minoxidil for hair growth. The original poster is considering adding stemoxydine to their hair loss treatment regimen.
The user discusses using dutasteride to stop hair loss and bimatoprost for regrowth. They plan to use VEGF with hydrogels for potentially permanent hair follicle improvement and suggest PRP as an alternative.
The conversation is about adding dermarolling to a hair loss treatment routine. The user seeks recommendations for dermarollers, stamps, or pens, emphasizing the importance of quality and proper cleaning.
The conversation is about using a Dr. Pen for microneedling on a widow's peak, with advice to use a depth of 1.25mm and hold it in place for 10 seconds. The user is also using minoxidil.
A user is considering mixing Stemoxydine, RU-58841, Alfatradiol, and Tretinoin into a single topical solution for hair loss. They are concerned about potential interactions that could reduce the effectiveness of these ingredients.
TDM-105795 showed better efficacy and safety in trials for hair loss, with a higher hair count improvement compared to GT20029 and HMI 115, but it's not as widely discussed. The user is questioning why this is the case.
The user shared progress pictures showing hair regrowth after 9 months using 1mg oral finasteride, topical Minoxidil, and Stemoxydine. They experienced a recent shedding at the hairline but are seeing new hair growth.
A user shared a 25-day progress picture showing significant hairline restoration attributed to microneedling, in addition to using minoxidil and finasteride for 6 months. Other users discussed needle length, frequency, and whether the effects of microneedling are permanent.
The post discusses the confusion about the optimal microneedling depth and frequency for hair growth, and when to apply treatments like minoxidil. A reply suggests the best method is using a 1.25mm depth every 7 days with a specific device, holding it for 10 seconds to stimulate hair growth.
A 38-year-old man from Poland, balding for 15 years, shared his hair regrowth progress after 4 months of using finasteride (fin), minoxidil (min), micro-needling, and infrared light treatments. He recently switched from finasteride to dutasteride.