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      community Update on PP405 Trails - Pelage

       14 upvotes 7 months ago
      The conversation discusses interest in participating in PP405 trials for hair loss treatment, with users expressing uncertainty about eligibility due to location. Participants are eager for updates and willing to pay for shipping if trials are limited to America.

      community Topical spironolactone — how many ml do you apply?

       6 upvotes 1 year ago
      The conversation discusses the use of topical spironolactone for hair loss, with the original poster applying 8 ml daily but learning that 2 ml is recommended. It also touches on hair transplants and the role of DHT sensitivity in hair loss, emphasizing individual differences in treatment outcomes.

      community Attacking DHT synergistically both locally at the scalp and systemically = Greater Success??

      in Finasteride/Dutasteride  15 upvotes 1 year ago
      The user has been using oral Dutasteride, RU58841, and Minoxidil for three years without success and is considering adding topical Finasteride or Dutasteride to target DHT both locally and systemically. Other users suggest sticking to a consistent treatment plan, exploring different combinations, and considering other factors like potential misdiagnosis or inconsistent medication use.

      community Can anyone else relate? M23. Pictures taken on the same day.

      in Styling  413 upvotes 1 year ago
      Hair looks thinner in sunlight, and users discuss using hair fibers, minoxidil, finasteride, and considering dutasteride for hair loss. Hair fibers like Toppik help conceal thinning, and some users suggest additional treatments like derma stamping and micro-needling.

      community Pp405 phase 2a clinical results

       37 upvotes 1 year ago
      PP405 shows initial promise for treating androgenetic alopecia, with safety confirmed in early trials, but skepticism remains due to limited data. Further trials are needed to determine its true efficacy and potential market impact.

      community 8 months apart - got all my hair back.

       4799 upvotes 1 year ago
      A user successfully regrew their hair over 8 months using topical minoxidil, finasteride, a healthy lifestyle, and derma stamping. They emphasize the results are genuine and not from hair transplants.

      community Quote from Pelage (PP-405) Spokesperson...

       122 upvotes 11 months ago
      Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.

      community Is it normal for scalp texture and appearance to change where hair is lost?

      in Transplants  9 upvotes 9 months ago
      The conversation discusses changes in scalp texture and appearance in areas of hair loss, with concerns about the suitability of these areas for hair transplants. Users mention issues like fibrosis, inflammation, and thinner skin, advising caution and consultation with clinics before proceeding with transplants.

      community topical latanoprost for hair loss?

       13 upvotes 4 years ago
      User 765bonazoli asked about experiences with Minoxidilmax topical latanoprost for hair loss. No specific treatments were mentioned in the provided text.

      community Verteporfin and KY19382 experiment

       80 upvotes 2 weeks ago
      The conversation discusses an experiment involving hair loss treatments, including the use of Verteporfin, KY19382, dutasteride, oral and topical minoxidil, AHK-Cu, and microneedling. The experiment aims to test the effectiveness of these treatments in promoting hair growth and healing without scarring, with updates planned every few months.

      community 4-month progress (dutasteride+minoxidil, 25y)

       1245 upvotes 4 weeks ago
      A 25-year-old shared their 4-month hair growth progress using minoxidil, dutasteride, and microneedling, claiming no side effects. Some users doubted the rapid transformation, while others praised the results.

      community 3,5 months of only topical minoxidil

       776 upvotes 9 months ago
      A 24-year-old reported new hair growth on temples after 3.5 months of using topical minoxidil without shedding. They plan to add finasteride to maintain progress, as minoxidil alone may not be enough long-term.

      community *11 month update* 1st pic 11 months ago vs today. 2nd pic same timeframe but wet hair. 3rd pic my hair at my worst back in 2020. 4th pic under bright lighting & camera flash. 5th pic hairline. 6th & 7th pic side/back view. 8th pic good hair day.

      in Progress Pictures  498 upvotes 2 years ago
      The user shared impressive hair regrowth results after 11 months using topical finasteride and minoxidil from HIMS. Many users congratulated the progress and inquired about the application method, brand, and potential side effects.

      community 8 months progress Before/After

      in Is this regrowth?  553 upvotes 1 year ago
      The user is pleased with their hair transplant results but is concerned about the vertex area. They use Minoxidil and finasteride daily and had the procedure at a clinic in Athens.

      community 1 years progress. Thoughts please?

      in Is this regrowth?  59 upvotes 1 year ago
      The user is using topical minoxidil and oral finasteride for hair regrowth, with plans for a future hair transplant. They are considering additional treatments like dermastamping and exploring options for dutasteride, which is unavailable in their country.

      community Slow and steady growth of hairline .One year progress

      in Is this regrowth?  6 upvotes 1 year ago
      The user experienced hair regrowth using topical finasteride 0.1%, minoxidil 10%, and microneedling over a year, recovering about 5 years of hairline and 3 years of density. The treatment was applied to the temples and frontal area, with some recovery in the coronal area attributed to microneedling.

      community A Short Recap on PP405 and AAD 2026

      in Update 5 months ago
      PP405 is a promising experimental topical treatment for alopecia that reactivates dormant hair follicles by targeting cellular energy, with large-scale trials planned for 2026. While it shows potential, it cannot regenerate permanently destroyed follicles, making hair transplants the only guaranteed solution for advanced baldness currently.

      community 3 months on topical fin/min/stamping

      in Is this regrowth?  95 upvotes 1 year ago
      The user has been using a topical combination of finasteride, minoxidil, and dermastamping for three months to address hair loss. They are considering adding tretinoin and are discussing the effectiveness of topical versus oral treatments.

      community My hair progress since Sept 2023

       471 upvotes 6 months ago
      The user started using finasteride and topical minoxidil in September 2023, later adding a Theradome laser helmet, which helped reduce hair shedding significantly. The user reports improved hair coverage and stability, attributing most progress to the medications rather than the helmet.

      community What's going on with hmi115? The Phase 2 was concluded Nov2024 but no news

       13 upvotes 9 months ago
      Hmi115, a prolactin receptor blocker, showed promise for hair growth, but results from Phase 2 trials have not been published. ABS-201, an AI-based analog, is expected to begin trials in December 2025, while commercialization of treatments like PP-405 is anticipated around 2027.

      community How are you using topical melatonin?

      in Treatment  1 upvotes 2 years ago
      The user is experimenting with topical melatonin for hair loss by dissolving melatonin tablets in a solution, but is having trouble with dissolution and is curious about others' methods of application and any effects on energy levels. They mention considering mixing with minoxidil but have not done so, and suggest that melatonin is best used at night.

      community Is anyone on topical spironolactone, or has anyone tried this?

       4 upvotes 5 months ago
      Topical spironolactone is discussed as a potential hair loss treatment for those who can't tolerate finasteride, with some users noting varied results and side effects. Alternatives like laser caps are also mentioned.