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GlossarySolid-Phase Extraction

method to isolate specific compounds from a mixture

Solid-Phase Extraction (SPE) is a method used in laboratories to separate and concentrate specific compounds from a mixture. It involves passing a liquid sample through a solid material (the "solid phase") that selectively adsorbs the target compounds, allowing impurities to be washed away. This technique is widely used in fields like environmental testing, pharmaceuticals, and biochemistry for sample preparation and purification.

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community Hair Transplant Results after 6 months . 3500 grafts. NW 6

in Progress Pictures 373 upvotes 6 months ago

The user underwent a hair transplant with 3500 grafts and has been using Finasteride and Minoxidil for 5.5 months, seeing some growth. They plan to have a second transplant for the crown area and are seeking opinions on future results and density improvement.

community How is it that golden era bodybuilders kept their hair while blasting gear while in the modern era most are bald? I’m convinced there’s something in our food and water causing MPB to speed up

in Satire 725 upvotes 1 year ago

The conversation is about the difference in hair loss between bodybuilders in the "Golden Era" and modern bodybuilders. Some users speculate that factors such as the types and doses of steroids used, genetics, diet, microplastics, and overall health may contribute to hair loss. Hair loss prevention medication and transplants are mentioned as potential treatments.

community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

in Research/Science 736 upvotes 1 year ago

A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

community Clearing the air on how non-surgical treatments really work

18 upvotes 5 years ago

Treatments for hair loss, including finasteride, dutasteride, minoxidil, ketoconazole, microneedling, and low level laser light therapy, which aim to reduce DHT production, increase cell absorption and blood flow, and stimulate epidermal stem cells. It also stresses the importance of patience when using these treatments.

community u/joaopassos4444 has zero education in endocrinology, human biology or science, it’s incredibly unlikely he good Will Hunting-ed a medical issue that stumped researchers for thousands of years, please stop buying random supplements based on layman speculation and temper your expectations

in Research/Science 69 upvotes 3 years ago

User questions credibility of a hair loss "cure" found by a non-expert and warns against wasting money on unproven supplements. Others discuss trying natural extracts and the importance of researching the enzyme 3ADH for potential hair growth benefits.

community Promising Topical Procyanidin B2 Treatment?

in Research/Science 29 upvotes 3 years ago

User discusses a promising topical Procyanidin B2 treatment for hair loss. Users share mixed experiences and mention effective treatments like finasteride, minoxidil, and LLLT.

community pyrilutamide phase 2 results right here, thanks to user Glaringbooch

in Chat 37 upvotes 2 years ago

Pyrilutamide, a new drug being tested to combat hair loss that has been found to perform comparably or better than finasteride and dutasteride in the initial 6 months of treatment with minimal reported side effects.

community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

in Research/Science 124 upvotes 8 months ago

The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

community CASSIOPEA ANNOUNCES VERY POSITIVE PHASE II TWELVE MONTHS RESULTS FOR BREEZULA® (CLASCOTERONE) IN TREATING ANDROGENETIC ALOPECIA

in Update 165 upvotes 5 years ago

Clascoterone (Breezula) showed positive results for treating hair loss without affecting cortisol levels. Opinions vary, with some users optimistic about its potential and others critical of its effectiveness compared to existing treatments like finasteride.

community Kintor has released an investor relations memo regarding Chinese Phase III trials for Pyrilutamide

in Update 54 upvotes 8 months ago

Kintor's Pyrilutamide (KX-826) showed hair growth in Chinese Phase III trials but did not significantly outperform placebo. The treatment was safe with no major adverse reactions reported.

community 3 Weeks After the Hair Transplant (before the ugly duckling phase). In my 20s, got some hope back

in Progress Pictures 292 upvotes 1 year ago

A user who underwent a hair transplant in their twenties and are now discussing the best treatments for long-term management of hair loss, such as finasteride and Minoxidil, as well as potential alternative treatment options like RU58841.

community 1 year of min+fin+ketoconazole

in Progress Pictures 1057 upvotes 4 months ago

The user has been using minoxidil daily, finasteride three times a week, and ketoconazole 1-3 times a week for a year to treat hair loss, resulting in noticeable hair regrowth at the hairline and temples, with minor side effects like itching and dandruff. They started with minoxidil a month before the other treatments and experienced an initial shedding phase for about six weeks.

community 5 years on Finasteride, 1.5 years on Minoxidil Foam

in Progress Pictures 707 upvotes 6 months ago

The user has been using finasteride for five years and minoxidil foam for 1.5 years to combat hair loss, experiencing significant regrowth after an initial shedding phase with minoxidil. They shared progress pictures and discussed treatment experiences, including the addition of minoxidil to their regimen after noticing reduced efficacy with finasteride alone.

community Hair Transplant result after one week

in Progress Pictures 587 upvotes 1 year ago

The post is about a user's hair transplant results after one week, with 4000 grafts implanted. The conversation includes discussions about the healing process, shedding phase, and the number of grafts used.

community discouraged about pyrilutamide

in Research/Science 11 upvotes 1 year ago

Discouragement regarding Pyrilutamide, a drug in development for hair loss, and the potential side effects of Finasteride. People discussed anecdotal experiences with Pyrilutamide as well as suggestions to wait out Phase 3 trials before making any conclusions.

community RU58841, Topical dutasteride minoxidil and tretonin, dermarolling, serioxyl, and redensyl for about 3 months. Each picture is about 2 weeks of growth. I used to have thick hair with big curls. Am I on track to get it back? Age 32

in Progress Pictures 25 upvotes 1 year ago

Treatments for hair loss, including topical dutasteride minoxidil, tretonin, dermarolling, serioxyl, and redensyl over a period of 3 months; switching from RU58841 to pyrilutamide was suggested with potentially less risk of systemic side effects; and encouragement to not give up hope.

community 1.5 year progress update 1mg Fin and 5% minoxidil

in Progress Pictures 343 upvotes 1 year ago

A user shared a 1.5-year hair loss treatment progress using 1mg Finasteride and 5% Minoxidil, planning to switch to oral Minoxidil and considering adding RU58841. They saw gradual improvement, suspecting Finasteride as the main contributor since they might not respond to topical Minoxidil.

community Anyone else just waiting until the real pyrilutamide and then GT20029?

in Chat 9 months ago

The user is hesitant to use finasteride due to potential hormonal side effects and is waiting for the release of pyrilutamide, a new hair loss treatment. Other users suggest trying finasteride, warning about potential regret if hair loss progresses in the meantime.

community Min + fin oral for eight months

in Progress Pictures 342 upvotes 3 months ago

The user shared progress pictures after using Minoxidil and oral Finasteride for eight months to treat hair loss. They experienced significant hair regrowth, and the discussion includes various opinions on the necessity and effectiveness of these treatments.

community What’s the deal with pyrilutamide?

in Research/Science 54 upvotes 2 years ago

The effectiveness of pyrilutamide, a hair loss treatment, with research results being postponed until September. Various people shared their experiences with topical finasteride, minoxidil and RU58841, as well as other treatments such as dandruff shampoo, group buys and grey markets.

community 6month update – it’s not much but it’s honest work (Fin/Min/Nizoral/Dermaroll) hair slightly thicker, waiting for my crown to fill 🤞

in Progress Pictures 175 upvotes 2 years ago

User reports 6-month progress using Fin, Min, Nizoral, and Dermaroll for hair loss. Others comment on visible improvement and suggest waiting up to 2 years for full effects.

community Thoughts? 4 months difference.

in Progress Pictures 176 upvotes 1 month ago

The user shared progress pictures showing hair regrowth after increasing the dose of topical Minoxidil and adding Finasteride. Replies indicate positive feedback and encouragement, noting visible improvement in the hairline.

community 3.5 months progress - oral dut 0.5mg and oral min 5mg - 26M

in Progress Pictures 140 upvotes 3 months ago

A user reports hair regrowth and thickening after 3.5 months using oral dutasteride (0.5mg) and oral minoxidil (5mg). They express gratitude for the information received from the community about hair loss treatments.

community 5 month progress finasteride 1mg

in Progress Pictures 1 year ago

A user's 5-month progress with Finasteride 1mg for hair loss, which is showing promising results; other users have suggested adding additional treatments such as Minoxidil and Derma Rolling to further boost regrowth.

community AnagenInc says GT20029 is possible now

in Research/Science 116 upvotes 1 year ago

AnagenInc is ready to produce a hair loss treatment called GT20029 if there is enough demand. People are discussing combining it with other treatments like finasteride and minoxidil, and some are concerned about the legitimacy and safety of gray market products.

community 3 Month Update – Topical Min (6%), Topical Fin (0.3%), 1.5mm Microneedle Weekly, 40 y/o

in Progress Pictures 99 upvotes 1 year ago

A user's 3-month update on their hair loss treatment, which consists of topical Minoxidil (6%), topical Finasteride (0.3%) and microneedling 1.5mm weekly; other users shared positive feedback and asked about the specifics of the treatments being used, such as product/brand, frequency, side effects and areas for microneedling.

community pyrilutamide GB update please? Anything no matter how big or small

in Update 32 upvotes 2 years ago

The effects of Finasteride on hair loss and its side-effects, such as aching balls. The user has been taking it for two years with no changes to the symptom.

community Any thoughts about Stemoxydine? I’ve been hearing good things about it.

in Research/Science 6 upvotes 3 years ago

The conversation is about the effectiveness of Stemoxydine for hair loss. People are discussing its benefits and comparing it to other treatments like Minoxidil, Finasteride, and RU58841.

community Hairfall is happening after 6 month of treatment and doctor doesn't give a F

in Finasteride/Dutasteride 1 month ago

User experienced major hair fall after six months of using minoxidil, finasteride, and dutasteride. Replies suggest the hair shedding is normal and will improve over time.

community Why are there no FDA approved NSAA's yet?

in Research/Science 3 months ago

The conversation discusses why there are no FDA-approved NSAAs like RU58841 on the market, despite their potential superiority to 5AR inhibitors like finasteride. It explores the effectiveness of treatments like Minoxidil, finasteride, and RU58841 for hair loss.