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      community Bile Acid-Mediated DHT Dysregulation Hypothesis

      in Research/Science  13 upvotes 1 month ago
      Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

      community Hairloss Treatment - General health and efficacy-conscious stack overview

      in Treatment 2 months ago
      The conversation discusses managing hair loss and seborrheic dermatitis with treatments like minoxidil, finasteride, and saw palmetto, emphasizing the importance of scalp health and DHT reduction. The user shares personal experiences and suggests a balanced approach, combining topical treatments and lifestyle changes for effective hair regrowth.

      community People who tolerate dut better than fin?

      in Finasteride/Dutasteride  32 upvotes 2 months ago
      Dutasteride may have fewer side effects than finasteride, with some users experiencing better hair maintenance. Experiences vary, with some preferring dutasteride for fewer side effects, while others see no significant hair improvement.

      community Does anyone else have experience with Patented Growth Factors (PGF) Treatments / experiences with depression on Fin/Min/Dut?

      in Treatment  1 upvotes 2 months ago
      The user is exploring hair loss treatments, including Patented Growth Factors (PGF) and a serum with Copper Peptide, Ceramides, Amino Acids, and Caffeine, while expressing concerns about the cost and effectiveness of PGF. They are also considering starting finasteride due to doubts about PGF's long-term viability and are seeking experiences from others who have used these treatments alongside antidepressants.

      community How to Add Tretinoin to 2 in 1 combo ?

      in Treatment  2 upvotes 5 months ago
      A user wants to add tretinoin to their nightly minoxidil and finasteride combo to increase effectiveness. They seek advice on how to mix tretinoin with the existing treatment.

      community Odd Hair Growth (Possibly More Than Genetics?)

      in Is this regrowth?  2 upvotes 5 months ago
      A 23-year-old user shares their hair regrowth journey, questioning if genetics or other factors are at play. They use Rogaine, finasteride, vitamin B12, biotin, Thera M Plus, and derma stamping, and seek advice on their regimen and hair growth patterns.

      community oral minoxidil collagen contradiction

      in Minoxidil  13 upvotes 6 months ago
      The conversation discusses concerns about oral minoxidil potentially aging the face by affecting collagen, questioning its systemic effects. The user has successfully used topical minoxidil for years and is hesitant to switch to oral minoxidil.

      community Anyone using oral castor oil in their stack?

      in Treatment  3 upvotes 6 months ago
      The conversation discusses using oral castor oil as a hair growth stimulant for beard and scalp hair. One user questions its use, noting castor oil is typically a laxative in the Philippines.

      community Tretinoin, any good, what’s your experience

      in Research/Science  20 upvotes 6 months ago
      The conversation discusses using tretinoin for hair loss and skincare. Users share experiences, noting tretinoin's effectiveness in combination with minoxidil for hair and its proven benefits for anti-aging skincare.

      community 8-months progress: dermarolling + supplements

      in Progress Pictures  261 upvotes 7 months ago
      A user shared an 8-month hair loss treatment progress using daily saw palmetto and biotin capsules, weekly dermarolling, and a scalp lotion mix of castor, jojoba, and rosemary oils, avoiding finasteride and minoxidil due to side effects and cost. The user reported encouraging progress with slight hairline improvement and better crown area, attributing most success to dermarolling.

      community Taurine supplements work for hair growth?

      in Product  8 upvotes 8 months ago
      The conversation discusses taurine supplements for hair growth, highlighting their potential to reduce DHT and improve hair health. A user comments that people often try alternatives to finasteride.

      community Fin is working; I’m just now noticing

      in Finasteride/Dutasteride  109 upvotes 9 months ago
      The user reports significant hair density improvement after 8.5 months of using finasteride, with no side effects except for initially watery semen. They also mention increased sex drive, which they attribute to finasteride, and regret not starting the treatment earlier due to fear of side effects.

      community Finasteride suddenly stopped working for me after almost 2 years of using it (M19)

      in Finasteride/Dutasteride  10 upvotes 9 months ago
      A user reported that after nearly 2 years of using finasteride with initial hair regrowth, their hairline worsened around day 570 and has not improved significantly since. They are considering switching to dutasteride or changing finasteride brands, while responders suggest the user may not actually be experiencing hair loss and might benefit from professional help.

      community Treating my DUPA via controlling inflammation

      in Treatment  6 upvotes 10 months ago
      The user has DUPA and suspects autoimmune activity as a cause. They have tried various treatments including finasteride, minoxidil, dutasteride, pyrilutamide, estrogel, hydrocortisone, and clobetasol, and are now seeking a long-term immunosuppressant.

      community Does low HGH leading to hairloss?

      in Research/Science  12 upvotes 10 months ago
      The user experiencing diffuse hair loss is using various treatments including RU58841, finasteride, minoxidil with tretinoin, anti-hair loss shampoo, and microneedling, and is considering adding peptides TB500, BPC157, and GHK-Cu. They have low growth hormone levels and are questioning its impact on hair loss, while another user suggests androgenic alopecia and androgens are likely the main cause of hair loss.

      community Tressless When They See Verteporfin Results

      in Transplants  182 upvotes 1 year ago
      The conversation discusses the potential of Verteporfin, an FDA-approved drug, for hair loss treatment, particularly in combination with microneedling or PRP. Users express hope and curiosity about its application, while some remain cautious due to the need for more extensive testing.

      community 48 days of Fin, Min, and Dermaroller

      in Progress Pictures  1740 upvotes 1 year ago
      The user has been using finasteride for hair loss for 2-3 years, and added 5% topical minoxidil and daily 1.5mm dermarolling to their routine 50 days ago, which resulted in significant hair growth. The user recommends dermarolling along with minoxidil and finasteride for better results.

      community Why is no one pointing out dandruff as the number 1 evidence/symptom of MPB?

      in Chat  55 upvotes 1 year ago
      The post discusses the theory that persistent dandruff in areas prone to hair loss could be a sign of hair follicles dying due to DHT, indicating balding. The responses vary, with some users noting improvements in dandruff and hair loss with treatments like Dutasteride, while others experienced hair loss without dandruff.

      community Dr. Bloxham's Verteporfin Trial

      in Research/Science  29 upvotes 1 year ago
      Dr. Bloxham's trial is testing verteporfin on hair transplant patients to see if it can improve hair regrowth in treated areas. People are discussing the potential for follicle regeneration, expected results timeline, and concerns about side effects like cancer.

      community I lost the fight against MPB at age 22 despite being on treatments.

      in Finasteride/Dutasteride  72 upvotes 1 year ago
      The user "ajsr8" shared their story of hair loss despite being on treatments. They started using finasteride in 2019 and later tried topical minoxidil, but it didn't seem to work. They also experienced side effects from other treatments. They are considering cutting off their hair and stopping the medications if there is no improvement in three months. Other users suggested trying different treatments and getting a blood test to check for underlying conditions.