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      community microneedle, any long term users damage?

      in Microneedling  35 upvotes 4 months ago
      Microneedling is effective for hair growth, especially when combined with finasteride and minoxidil, but concerns exist about potential long-term skin damage. Users report increased collagen and elastin deposition, but the long-term effects on the scalp remain uncertain.

      community Anyone Try Microneedling with Exosomes/AAPE?

      in Microneedling  2 upvotes 2 years ago
      User asks where to purchase exosomes/AAPE for microneedling hair loss treatment. Links to research on hair regeneration therapy, stem cell therapy, exosome therapy, and dermal exosomes provided.

      community Expectations control for SCUBE3

      in Research/Science  21 upvotes 6 months ago
      SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

      community What regimen do I need to get this hairline?

      in Satire  362 upvotes 1 year ago
      Discussing a regimen to improve the user's hairline, with treatments proposed including minoxidil, rectal microneedling, IV drip of minoxidil, laser removal, PRP injection, topical minoxidil, divine protein shakes, stem cell injections, and keto shampoo.

      community Clearing the air on how non-surgical treatments really work

       16 upvotes 5 years ago
      Treatments for hair loss, including finasteride, dutasteride, minoxidil, ketoconazole, microneedling, and low level laser light therapy, which aim to reduce DHT production, increase cell absorption and blood flow, and stimulate epidermal stem cells. It also stresses the importance of patience when using these treatments.

      community Best Microneedle Lengths To Stimulate Stem Cells

      in Microneedling  18 upvotes 11 months ago
      Microneedling with needle lengths of 1.5mm to 2.5mm to stimulate hair follicle stem cells for potential hair growth. Using needles longer than 2.5mm is not recommended due to risk of puncturing veins in the scalp. A dermastamp is suggested over a roller.

      community 21 Month Finasteride+13 Month Minoxidil+2 Month Stemoxydine

      in Finasteride/Dutasteride  88 upvotes 11 months ago
      The post discusses a 21-month treatment of hair loss using Finasteride, a 13-month treatment with Minoxidil, and a 2-month treatment with Stemoxydine. Replies suggest enhancing results by adding a micro needling pen and tretinoin to the regimen, and consider Finasteride and Minoxidil as crucial treatments.

      community Will Hair cloning actually work? Could it actually be here by next year or so, as they're saying? I don't think it will be here so soon, but maybe in the next 5 years? I'm a diffuse thinner so hairline doesn't seem much of a worry for me now...

      in Chat  9 upvotes 2 years ago
      Hair cloning is discussed as a potential future solution for hair loss, but it's not expected to be available soon due to high costs and technical challenges. Current treatments like Minoxidil, finasteride, and RU58841 are not mentioned in this conversation.

      community The Worst Hair Loss Condition You (MAY) have: LPP

      in Research/Science  43 upvotes 1 month ago
      Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

      community Verteporfin and Microneedling

      in Treatments 3 months ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

      community NootBro Recommendations… How Do We Feel

      in Research/Science  9 upvotes 4 months ago
      The conversation is about hair loss treatments, specifically a stack including topical Ashwagandha, Copper Peptide, Gotu Kola, Ketoconazole, and PDA. One user found Topical and Sub-Q GHK-CU effective.

      community When you spray minoxidil all over your face

      in Satire  270 upvotes 5 months ago
      The conversation is a humorous discussion about excessive hair growth due to using minoxidil, with suggestions of laser hair removal and comments on the appearance of the hair. Some users joke about starting finasteride treatment at a young age or being non-responders to hair loss treatments.

      community Growth Stimulants that aren't Minoxidil...?

      in Research/Science  8 upvotes 5 months ago
      The user is exploring hair growth stimulants other than Minoxidil, mentioning Stemoxydine, various peptides, drugs like Latanoprost and Bimatoprost, and natural remedies such as Rosemary Oil and Caffeine. They express concerns about the long-term effectiveness and safety of these alternatives and seek more information on viable options for hair regrowth.

      community Keratin microspheres - breakthrough

      in Research/Science  13 upvotes 6 months ago
      A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

      community M32, almost 3 moths, fin oral 1,25g/daily + min 2xday + keto 2% shapoo 1/week microneedling once a week

      in Progress Pictures  31 upvotes 10 months ago
      A 32-year-old man has been treating his hair loss with daily oral finasteride (1.25g), twice-daily topical minoxidil, weekly ketoconazole 2% shampoo, and weekly microneedling for almost three months, with no side effects from finasteride. He started with a Hamilton Norwood scale rating of 5 and has seen improvement without experiencing pain by using a 0.8mm needle length for microneedling.

      community Does melatonin dissolve in isopropyl alcohol

      in Technology  8 upvotes 1 year ago
      The conversation discusses making a topical melatonin solution for hair loss treatment, questioning if isopropyl alcohol can dissolve melatonin. Melatonin is soluble in lipids and alcohol, but it's unstable and should be mixed fresh regularly; it may help hair growth by affecting certain cellular signaling pathways and has anti-androgenic effects.

      community How are you guys using tretinoin on your scalp?

      in Treatment  6 upvotes 1 year ago
      People are discussing how to apply tretinoin to the scalp for hair loss treatment and managing scalp dryness. Specific treatments mentioned include tretinoin, minoxidil (Min), finasteride (Fin), and RU58841 (RU).

      community Comprehensive Microneedling Guide

      in Microneedling  289 upvotes 2 years ago
      Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

      community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

      in Research/Science  92 upvotes 2 years ago
      The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.

      community Any young women losing hair that have tried microneedling and oils?

      in Microneedling  33 upvotes 4 years ago
      A 25-year-old woman is experiencing hair loss and has started microneedling with a 0.5mm roller, applying a mix of essential oils overnight. She questions whether to switch to a 1.5mm roller and the best order for her routine, while a reply suggests using Minoxidil for better results.