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      community Melatonin a possible tool to help fight AGA hair loss.

      in Research/Science  52 upvotes 3 years ago
      Topical melatonin may help reduce hair loss and increase hair thickness in people with androgenetic alopecia (AGA), with some studies showing positive results. It can be mixed with minoxidil for application, and its effectiveness might be enhanced when used with micro-needling, but results may vary among individuals.

      community 9months progress fin/derma pen/minoxidil

      in Progress Pictures  1001 upvotes 4 years ago
      A user's 9 month progress using Finasteride, Derma Pen/Roller and Minoxidil to treat hair loss. Replies in the conversation include advice on topical application of Minoxidil and Dutasteride for regrowth and hair thickness.

      community Injecting stomach fat into the scalp could cure baldness in just six months

      in Update  114 upvotes 6 years ago
      A potential treatment for hair loss that involves injecting fat into the scalp; the role of testosterone and estrogen in thinning fat tissue under the skin; research on using lard to treat androgenic alopecia, as well as PRP + ACELL/amniotic stem cell treatments; and ongoing clinical trials by doctors involved in the study.

      community What I've Learned: A Quality of Life Guide

       78 upvotes 7 years ago
      The post discusses hair loss treatments, specifically using minoxidil, finasteride, nizoral, and sulfur-including shampoo. The author shares personal experiences and tips for application, frequency, and managing side effects, noting significant regrowth with both minoxidil and finasteride.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 2 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Topical is superior to oral in terms of results (my theory)

      in Finasteride/Dutasteride  61 upvotes 7 months ago
      The conversation discusses the use of topical minoxidil and finasteride for hair loss, with some users combining them with oral treatments. Users share their experiences and opinions on effectiveness, cost, and convenience, with mixed views on whether topical or oral applications are superior.

      community 1 Year Progress On 0.5mg Finasteride + 5mg Minoxidil

      in Progress Pictures  1316 upvotes 6 months ago
      A user shared a 1-year progress on hair loss treatment using 0.5mg of oral finasteride and 5mg of oral minoxidil, showing significant hair regrowth from almost bald to much thicker hair. Other users discussed their own experiences with these treatments, with some preferring topical applications to avoid side effects.

      community What ever happened to pyrilutamide?

      in Technology  48 upvotes 1 year ago
      Pyrilutamide, a potentially effective hair loss treatment; other topical treatments like RU58841 and CB-03-01 that may have fewer side effects than Pyrilutamide; and the Phase 3 clinical trials of Pyrilutamide, which is likely to be approved by the FDA soon.

      community Using essential oils as well as minoxidil?

      in Minoxidil  6 upvotes 6 years ago
      The conversation is about using a blend of coconut oil, peppermint oil, and rosemary oil with minoxidil for hair loss, and whether it's safe to apply this blend after microneedling.

      community Solo use of Pyrilutamide: UPDATE

      in Update  45 upvotes 1 year ago
      A user who has been using Pyrilutamide for 19 days, experiencing some hair thickening in the right temple and crown area but also having ball ache after microneedling; other users offer advice, caution and skepticism as to whether results can be seen in such a short time.

      community Anyone Try Microneedling with Exosomes/AAPE?

      in Microneedling  2 upvotes 2 years ago
      User asks where to purchase exosomes/AAPE for microneedling hair loss treatment. Links to research on hair regeneration therapy, stem cell therapy, exosome therapy, and dermal exosomes provided.

      community Is microneedling + minoxidil better than oral minoxidil

      in Chat  29 upvotes 1 week ago
      Oral minoxidil is considered more effective for hair regrowth than topical minoxidil, but it carries higher risks. Combining microneedling with topical minoxidil can enhance absorption, but oral minoxidil with microneedling shows significant results.

      community Minoxidil with tretinoin usage frequency

      in Minoxidil  3 upvotes 3 months ago
      The conversation is about using tretinoin with minoxidil for hair loss treatment. The user is seeking advice on usage frequency and results after adding tretinoin to their regimen.

      community 39m 1.1mg finasteride 3mg oral minoxidil

      in Progress Pictures  16 upvotes 8 months ago
      A user shared their progress using 1.1mg oral finasteride and 3mg oral minoxidil since January 2024, noting significant improvement without side effects. They previously had an allergic reaction to topical treatments.

      community I hate it when people write off your hairloss info because “you’re not a doctor.”

      in Treatment  76 upvotes 1 year ago
      A user shared their frustration about their cousin's refusal to take their advice on using finasteride for aggressive hair loss, despite the cousin's desperation and current use of minoxidil and consideration of PRP injections. The user, who has done extensive research, suggested the cousin needs a 5ar inhibitor, but the cousin dismisses the advice because the user isn't a doctor.

      community 3-4 Months of consistent use of Hims Fin/Min Spray

      in Progress Pictures  540 upvotes 1 year ago
      The user, Virtual_Force3845, shared their progress pictures after using Hims Fin/Min Spray consistently for 3-4 months. They are excited about the progress and have not experienced any side effects. Other users in the conversation shared their own experiences and asked questions about the treatment.

      community Hold up... CosmeRNA/SAMiRNA is actually coming real soon?

      in Technology  31 upvotes 1 year ago
      A user discovered CosmeRNA, a new hair loss treatment with clinical research backing, set to release soon. The conversation revolves around its potential effectiveness, cost, and how it compares to existing treatments like Minoxidil and Finasteride, with some users expressing hope for a side-effect-free option.

      community Extreme regimen and still miniaturized hairs. AGA is just impossible to beat.

      in Insane  32 upvotes 1 year ago
      A user's extreme regimen for hair loss, which includes taking oral and topical medications such as minoxidil, dutasteride, cyproterone acetate and bicalutamide, but still experiencing miniaturization. Suggestions were made to try other treatments such as RU58841 and Pyrilutamide, while also considering mental health treatment and advice on lookmaxxing.

      community Dr. Kyle Gillet on Dr. Andrew Huberman's podcast said dutasteride mesotherapy blocks DHT conversion only in the scalp and called it the most promising topical currently. What's the scoop?

      in Treatment  24 upvotes 2 years ago
      Dr. Kyle Gillet mentioned on Dr. Andrew Huberman's podcast that dutasteride mesotherapy blocks DHT conversion only in the scalp and is the most promising topical treatment. Users discussed concerns about systemic absorption and the practicality of dutasteride injections.

      community Dermaroller vs dermastamp vs dermapen

      in Microneedling  5 upvotes 1 day ago
      Microneedling is debated for hair loss treatment, with some users finding it beneficial for minoxidil absorption and others skeptical of its effectiveness. Alternatives like finasteride and minoxidil are recommended, while tools like dermarollers, dermapens, and dermastamps are discussed for their pros and cons.