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A 26-year-old had 2,060 grafts transplanted in Bogotá, Colombia, and is using oral Minoxidil 2.5mg twice daily. They are not using Finasteride.

People are discussing their reactions if PP405 fails in phase 3 trials, with some expressing skepticism and others holding onto hope for future treatments like GT20029 and Breezula. Many mention continuing with existing treatments like minoxidil and finasteride, while others express disappointment and consider alternative solutions.

PP405 trials have completed phase 2a, showing promising results with a 31% stat for hair density increase, and are moving directly to phase 3. Detailed results will be presented at a medical conference in 2026.

Kintor Pharmaceutical's KX-826 shows promising results for hair loss treatment. Users discuss the use of anti-androgens like spironolactone and RU58841, noting concerns about concentration and safety.

White spots on a bald scalp, likely tinea versicolor, can be treated with ketoconazole or selenium sulfide shampoos like Selsun Blue. Consulting a dermatologist is recommended for proper diagnosis and treatment.

Stemoxydine's effects on hair growth are uncertain and not well-studied, with users reporting mixed results and concerns about maintaining gains. Some users combine it with 5AR inhibitors like Dutasteride, but results vary, and conditions like lichen planopilaris complicate treatment.

Oral PTD-DBM was discussed as a potential hair loss treatment, but it was deemed ineffective in humans despite promising results in mice. The conversation concluded that trying it without VPA might be unwise.

Seborrheic dermatitis can cause hair loss, and treatments like ketoconazole shampoo, topical steroids, and oral antifungals may help. Some consider using finasteride and minoxidil for hair loss despite dermatitis.

Scientists discovered a sugar gel, 2dDR-SA, that increased hair growth in mice. Users discussed its potential, comparing it to other treatments like Minoxidil and finasteride.

Kintor's phase III trial for pyri (KX-826) showed promising safety and efficacy results, with no drug-related sexual dysfunction reported. Users discussed their experiences with pyri, Minoxidil, Dutasteride, and concerns about the validity of the study results.

Clascoterone solution is in Phase III trials for male androgenetic alopecia, with results expected in the second half of 2025. Commercialization is anticipated in about 2-3 years, but there are concerns about delays and market expectations.

The conversation discusses liver issues potentially linked to long-term use of finasteride and dutasteride, with users sharing similar experiences of elevated liver enzymes, high cholesterol, and other health concerns. The consensus suggests stopping the medication and consulting a healthcare professional for proper diagnosis and treatment.

The conversation discusses using CB0301/Clascoterone as a potential treatment for hair loss, especially for those experiencing side effects from finasteride and dutasteride. The user currently uses oral minoxidil and considers combining it with other treatments like kx826, DHT blocker supplements, and 2% Nizoral shampoo.

Oral biotin combined with topical minoxidil may increase hair growth rate, though the study was limited to healthy subjects and did not measure hair density. Some users report personal benefits from biotin, such as faster nail growth and healthier hair, but concerns about acne and study quality were also mentioned.

The conversation discusses using estradiol mesotherapy to replicate hormone replacement therapy results while minimizing systemic exposure. It also covers the use of Spironolactone cream, which reportedly has no systemic side effects, and the potential risks of using bicalutamide and Spironolactone in men.

Amplifica is testing a compound called AMP-303 for hair loss, but it's not Scube3 or osteopontin. The timing for the results from the clinical trial is unknown.

CB-03-01, also known as Breezula, is being considered as an alternative to DHT blockers for hair loss. Users are discussing its effectiveness, potential regrowth, side effects like scalp irritation, and hormonal impacts.

Topical pirfenidone is highlighted as an effective anti-inflammatory and anti-fibrotic treatment for hair loss, particularly in addressing perifollicular fibrosis, which may enhance the effectiveness of standard treatments like finasteride and minoxidil. The user also uses calcipotriol, MCT oil, ciclopirox shampoo, and benzoyl peroxide shampoo as part of their regimen.

Rice water was used as a hair treatment and showed noticeable results in a week, more than finasteride used for seven months. The user plans to continue using rice water and might stop finasteride, while still using ketoconazole for dandruff.

Emerging hair loss treatments like PP405, a topical MPC inhibitor, show promise in activating stem cells for hair growth. The conversation seeks information on the development stages and accessibility of these treatments.

The user has been using finasteride for four years and topical minoxidil with microneedling for a year but has not seen significant results in slowing hair loss. They are considering trying dutasteride despite concerns about its intensity, and others suggest trying oral minoxidil or combining treatments for better results.

A 20-year-old is considering using topical spironolactone for hair loss after experiencing side effects from finasteride. Another user shares their regimen, which includes dutasteride, spironolactone, cetirizine, and minoxidil, while caution is advised against spironolactone due to potential systemic effects.

Adding topical spironolactone to a finasteride regimen for hair loss. Users discuss different mechanisms and suggest also using minoxidil.

Finasteride can cause sexual side effects, and reducing porn and masturbation may help improve sexual function. Some users experience persistent issues even after stopping finasteride.

Excessive sugar and high-fat diets are linked to male pattern hair loss, with sweet beverages being a significant factor. Moderation in diet is advised, as diet alone may not fully prevent hair loss due to other factors like DHT sensitivity.

Excessive sugar consumption may contribute to male pattern hair loss by increasing androgen sensitivity and insulin resistance, but genetics play a significant role. Treatments like minoxidil and finasteride are suggested for managing hair loss, while reducing sugar intake and maintaining a healthy lifestyle may help mitigate its progression.

The conversation discusses a user's worsening scalp condition, possibly seborrheic dermatitis, despite using keto shampoo. Suggestions include using MCT C8 oil, adjusting diet by reducing carbs and sugars, and consulting a dermatologist.

Topical spironolactone was ineffective for hair loss according to one user who tried 2% nightly for a few months. The user reported no results.

The conversation discusses scalp issues, with the original poster experiencing itchiness and a white layer on the scalp despite using ketoconazole shampoo. Suggestions include using rosemary oil for moisturizing and trying a hair serum to reduce flakes.

ABS-201 shows promise for male hair regrowth by blocking the prolactin receptor, with higher expected efficacy than current treatments. The discussion also covers dosing differences between macaques and humans for hmi115, highlighting a significant dosage disparity.