The conversation discusses hair loss treatments, specifically RU58841, with mentions of side effects from finasteride and dutasteride. Alternatives like Pyri, KX-826, and Breezula are also mentioned.
A user shared their 88-day progress using 1.25mg finasteride, topical minoxidil, and weekly 1mm microneedling, noting improvement from NW 4.5 to around NW 3. Another user complimented the progress.
The user shared their hair loss transformation and treatment routine, which includes dutasteride, finasteride, various forms of minoxidil, and other topical treatments. They emphasized consistency in their regimen and offered to answer questions about their experience.
People are hopeful about future hair loss treatments like PP405, GT20029, and VDPHL01, while some are currently using finasteride and minoxidil. There is skepticism about the effectiveness of new treatments, and some advise against hair transplants until more promising drugs are available.
A satirical discussion about a hair transplant, with humorous comments on graft placement and clinic choice. The conversation includes references to a "Rebuild a Scalp Clinic" and jokes about using pubic hair and overharvesting.
RU-58642 is a powerful anti-androgen that was not developed further, possibly due to safety concerns or financial reasons. RU58841 is a topical alternative, but it is less effective than finasteride and dutasteride, and its long-term effects are not well-studied.
The conversation is about hair loss treatment progress using a combination of 0.1% finasteride, 0.025% tretinoin solution, and 2.5mg oral minoxidil. Users express positive reactions and hope for similar results.
The conversation is about using minoxidil and a dermaroller for hair loss treatment, with progress seen after 8 months. The user applies topical minoxidil twice daily and uses a dermaroller once a week, avoiding minoxidil 12 hours before and after rolling.
RU58841 and topical GHK-CU are used together for hair loss, with RU58841 reducing shedding and GHK-CU improving scalp health. Users report noticeable hair growth and improved hair quality within weeks, especially when used consistently.
The user is using oral finasteride daily, topical minoxidil 5-6 days a week, tretinoin before minoxidil 3 times a week, and dermastamping weekly for hair loss treatment. They are considering adding dutasteride to their regimen and have not experienced any side effects from finasteride.
Clascoterone's full trial results are expected by mid-July 2026, but skepticism exists about timely release. Clascoterone is available at 5% from some telehealth companies.
The conversation is about hair loss treatments, specifically discussing the use of dutasteride (DUT), minoxidil (Min), spironolactone, RU58841, and pyrilutamide. The user is considering increasing DUT dosage and exploring microneedling with topical treatments.
The user is discussing hair regrowth after 7 months of using topical minoxidil and RU58841, with some microneedling. They are hesitant to switch to finasteride or dutasteride and are seeking input on whether there is new growth or just more miniaturization.
SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.
A user shared a 9-month update on using 0.25mg finasteride daily for hair maintenance, reporting no significant side effects and considering whether to add other treatments like a dermastamp or ketoconazole. The user has not used minoxidil, believes it's unnecessary unless hair loss is severe, and occasionally takes biotin supplements.
The user is considering adding a topical treatment to their current regimen of finasteride and oral minoxidil to protect their temple area, with options like piro, RU58841, or topical finasteride or dutasteride. They are advised against overcomplicating their treatment, but another user suggests a topical with 8% minoxidil/dutasteride for better results.
GT20029, a new hair loss treatment, shows promising results but only a slight improvement over placebo. People are cautiously optimistic, discussing its potential and combining it with existing treatments like Minoxidil and Finasteride.
The conversation discusses experiences with mixing KY19382 with PEG400 or other mixtures for hair loss treatment. It also mentions interest in a group purchase of KY19382 or other hair loss research powders.
The user is experiencing positive results in hair regrowth using a protocol that includes minoxidil, dutasteride, essential growth serum, argan oil, trioxidil shampoo, ketoconazole shampoo, and microneedling. They express hope and satisfaction with the progress after six weeks of treatment.
KX-826 Phase II results show that a 0.5% concentration performs better than 1% for treating male pattern baldness. Concerns about receptor upregulation from long-term DHT antagonism were mentioned.
A 21-year-old is experiencing hair loss and has been using finasteride, minoxidil, and recently added dutasteride to their treatment. They have seen some progress and are considering a hair transplant if needed, but are not aiming for full recovery.
PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.
The user experienced hair regrowth after 7 months of using finasteride, minoxidil, and ketoconazole shampoo, with shedding stopping recently. They reported no side effects and use a minimal oral dose of minoxidil.
The user was rejected from participating in a clinical trial for an extended-release oral Minoxidil due to having rheumatoid arthritis, despite initially being accepted. They had stopped using Dutasteride and Minoxidil to qualify but continued using other treatments like RU58841 and red light therapy.
The user is thrilled with their hair transplant results after 9 months, having received 3200 grafts and using dutasteride and minoxidil daily. They recommend the procedure, noting it cost a little over $5000 at Max Hair Clinic in Bangkok.
The user reported positive results using KX-826 0.5% twice daily for hair loss, noting progress in the temple area with no systemic side effects. They avoided finasteride and minoxidil due to concerns about side effects and inconvenience, respectively, and used ketoconazole shampoo for seborrheic dermatitis.
The user is pleased with their hair transplant results after nearly 7 months, noting thicker, longer, and stronger hair with good coverage and full donor recovery. They are using oral minoxidil and finasteride.
A user plans to use RU58841 with stemoxydine and nizoral for hair loss, considering finasteride later. Others share mixed experiences with RU58841, some reporting no side effects and others experiencing issues like chest tightness, while some suggest combining it with finasteride and minoxidil for better results.
A user is considering using topical finasteride, topical minoxidil, RU58841, and dermarolling twice a week to address hair loss after experiencing side effects with oral finasteride. They previously saw positive results with a topical spray containing finasteride, minoxidil, and tretinoin but discontinued use due to laziness.
The conversation discusses the safety study of PP405, emphasizing that early trials focus on safety rather than efficacy, and that any efficacy data from such a short study should be viewed skeptically. It also highlights that the information released is primarily for securing funding, and that meaningful efficacy results are expected in later phases.