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GlossarySensitivity

ability to detect or respond to specific stimuli

Sensitivity, in the context of biology and medicine, refers to the ability of an organism or a specific part of the body to respond to stimuli. For example, skin sensitivity can indicate how the skin reacts to touch, temperature, or allergens. In diagnostic testing, sensitivity measures how effectively a test identifies true positives, meaning it correctly detects individuals who have a particular condition.

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community Having androgen receptor density and sensitivity at wrong f*ing place

in Satire 7 upvotes 2 months ago

The conversation discusses hair loss treatments, focusing on the use of topical minoxidil, microneedling, finasteride, and dutasteride, while debating the role of testosterone and DHT in hair loss. It also touches on the potential liver health impacts of these treatments and the genetic sensitivity of hair follicles to androgens.

community If we lose hair because of our sensitivity to DHT, then why are we trying to reduce DHT when our sensitive androgen receptors are the culprit?

in Finasteride/Dutasteride 13 upvotes 2 years ago

The conversation discusses the effectiveness of reducing DHT for hair loss treatment and explores alternative approaches like reducing androgen receptor sensitivity. Specific treatments mentioned include finasteride, dutasteride, pyrilutamide (KX-826), GT20029, and RU58841.

community I find it crazy how some people like this bloke have 0 DHT sensitivity. He is on grams of anabolic steroids and has a full, thick head of hair. I wish all of on here had this guys hair genes lol

in Satire 443 upvotes 1 year ago

The conversation is about hair loss and the possibility of maintaining a full head of hair while using anabolic steroids. Some users believe that having good hair genes and taking hair loss protocols can help prevent hair loss while on steroids.

community [M19] Dutasteride, is this the start of gyno growth or just nipple sensitivity?

in Finasteride 113 upvotes 1 day ago

A 19-year-old male switched from finasteride and minoxidil to dutasteride due to continued hair thinning and is experiencing increased nipple sensitivity and a small lump, raising concerns about gynecomastia. Suggestions include slowing the transition, checking hormone levels, and considering an aromatase inhibitor.

community What actually causes hair loss / androgenic alopecia?

in Chat 8 upvotes 2 weeks ago

DHT sensitivity at the scalp increases with age, contributing to androgenic alopecia. Treatments like Minoxidil, finasteride, and RU58841 are discussed for managing hair loss.

community Stress make you more androgen sensitive

in Chat 19 upvotes 6 months ago

Stress can increase androgen sensitivity, potentially worsening hair loss. Treatments discussed include Minoxidil, finasteride, and RU58841.

community How does hair loss and recovery work?

in Chat 12 upvotes 3 months ago

Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

community Why does finasteride stop working?

in Finasteride/Dutasteride 26 upvotes 2 months ago

Finasteride may seem less effective over time due to increased DHT sensitivity or aging, but it still suppresses DHT. Switching to dutasteride offers stronger DHT suppression but may increase estrogen levels.

community Running my hands through my hair, can’t remember what normal looked like, is this normal?

in Chat 19 upvotes 6 months ago

A 17-year-old experiencing hair thinning uses dermarolling with rosemary oil and plans to start finasteride at 18. A reply suggests using finasteride and minoxidil due to high DHT sensitivity.

community thoughts on topical Saw Palmetto oil

in Treatment 4 upvotes 6 months ago

The user is considering topical Saw Palmetto or Pumpkin Seed Oil due to sensitivity to finasteride and cost issues. They also use dermastamping for Minoxidil absorption and seek advice on timing to avoid systemic absorption.

community Do we know exactly why some people respond so great to dut/fin,min and others dont?

in Research/Science 29 upvotes 1 month ago

Genetic factors, enzyme activity, and DHT sensitivity affect individual responses to hair loss treatments like finasteride, minoxidil, and dutasteride. Starting treatments early can slow hair loss, but results vary among individuals.

community Topical minoxidil and Body hair

in Minoxidil 6 upvotes 1 year ago

Topical minoxidil can cause increased body hair due to systemic absorption, varying by individual skin sensitivity. The user seeks experiences and solutions to prevent this side effect.

community I want to sacrifice my hair in the name of science

in Chat 12 upvotes 1 year ago

The conversation discusses various theories of hair loss, including DHT sensitivity and genetic factors, with the user willing to use themselves for research due to having a hair loss gene but different hair loss patterns compared to their brothers. Specific treatments were not mentioned in the provided text.

community any news about DUPA (Diffuse unpatterned alopecia)?

in Research/Science 9 upvotes 2 years ago

The conversation discusses diffuse unpatterned alopecia (DUPA) and its possible causes, including sensitivity to DHT, not being androgenic alopecia, being diffuse alopecia areata, or hormonal issues. Treatments mentioned include topical melatonin, Clobetasol Propionate for alopecia areata, and the lack of results from using finasteride, dutasteride, and minoxidil.

community One month experience on Fin 1mg/day

in Finasteride/Dutasteride 7 upvotes 2 years ago

A 28-year-old started finasteride 1mg/day for hair loss, later reducing to 3 times a week. Positive effects include better gym performance, reduced social anxiety, and improved skin health, while negative effects include some erectile dysfunction and nipple sensitivity.

community P5P supplementation for fin sides.

in Treatment 7 upvotes 2 years ago

P5P supplementation helped reverse finasteride side effects, particularly by lowering prolactin levels and restoring sensitivity. The user experienced significant improvement within a day and full recovery in a few days.

community Hair loss causes are still a myth.

in Chat 16 upvotes 3 years ago

The conversation discusses the complexity of hair loss causes, suggesting that DHT sensitivity alone doesn't fully explain it. Treatments mentioned include finasteride and dutasteride.

community Fin non responders, did Dut ever work? Please share!

in Finasteride/Dutasteride 17 upvotes 4 days ago

The conversation discusses the effectiveness of finasteride and dutasteride for hair loss, with some users finding no improvement and experiencing side effects. It also mentions the use of RU58841 and topical minoxidil, highlighting that hair sensitivity to DHT varies among individuals.

community Why do people say you will have an extremely high chance of maintenance if you are on Dutasteride, if 0.5 mg only removes 50% of scalp dht

in Finasteride/Dutasteride 30 upvotes 2 weeks ago

Dutasteride and finasteride are effective for many in reducing hair loss by lowering DHT levels, though results vary based on individual sensitivity and genetics. Higher doses of dutasteride may not significantly increase hair growth due to diminishing returns, and topical finasteride is suggested as an alternative for some.

community Minoxidil Sulfate makes everyone a responder

in Research/Science 255 upvotes 1 month ago

Minoxidil sulfate is more effective than regular minoxidil, especially for those with low sulfotransferase levels or scalp sensitivity, but it is unstable unless delivered in a liposomal format. Combining minoxidil with tretinoin can enhance effectiveness, and stopping minoxidil use can lead to rapid hair loss.

community Attention Finasteride / Dutasteride and Your liver

in Finasteride/Dutasteride 373 upvotes 1 month ago

Finasteride may cause elevated liver enzymes, potentially leading to liver issues, though this is rare. Users should monitor liver function and consider topical alternatives if liver sensitivity occurs.

community M 23 progress 2 Months fin and min

in Progress Pictures 15 upvotes 2 months ago

A 23-year-old male shares progress pictures after two months of using oral finasteride and topical minoxidil for hair loss, noting significant improvement in hair fullness and reduced scalp sensitivity. The user expresses gratitude for the dermatologist's support and the community's advice.

community Help! Minoxidil or Duta to avoid Shed of long hair.

in Female 6 upvotes 2 months ago

The user is considering using Tacrolimus Solution and topical Dutasteride to avoid shedding caused by Minoxidil, which they fear may lead to facial side effects. They are also concerned about scalp sensitivity and are exploring different treatment bases to manage seborrheic dermatitis.

community Do you ever use your Dr pen for your face after microneedling your scalp ?

in Microneedling 11 upvotes 6 months ago

The conversation discusses using a microneedling device on the face after using it on the scalp, with suggestions to use a depth of 0.2mm for facial treatments. Caution and proper sterilization are advised due to the sensitivity of facial skin.

community If dutesteride and oral minoxidil doesn’t work that’s it right?

in Treatment 20 upvotes 7 months ago

A user is experiencing continued hair loss despite using 0.5mg dutasteride and 2.5mg minoxidil, and is seeking advice on why the treatments aren't working and how to address potential androgen receptor sensitivity. Replies suggest getting tested and considering scalp micropigmentation (SMP).

community Why is it that low testosterone causes hair loss as well? How can I be balding?

in Chat 158 upvotes 8 months ago

The conversation discusses the confusion over low testosterone potentially causing hair loss, with users sharing personal experiences and knowledge about hair loss treatments like Finasteride. Some users suggest that hair follicle sensitivity to DHT, not testosterone levels, is the key factor in balding, and others discuss the side effects of hair loss medications.

community Low testosterone and dht. What should I do?

in Finasteride/Dutasteride 6 upvotes 9 months ago

The user has low testosterone and DHT levels and is considering taking finasteride for Norwood 2 hair loss with diffuse thinning. They are seeking advice on whether low DHT indicates high sensitivity to DHT in the scalp and opinions on their lab values.

community How do you apply minoxidil with long hair?

in Minoxidil 8 upvotes 9 months ago

The user has trouble applying minoxidil foam to their long, curly hair and experiences product buildup, leading to frequent hair washing. They are considering switching to liquid minoxidil but are concerned about scalp sensitivity and do not want to use oral treatments. Another user suggests that topical minoxidil doesn't need to be applied to the entire scalp to be effective.

community Why do some have no change even on nuclear stacks ?

in Research/Science 16 upvotes 10 months ago

Some people see significant hair regrowth using treatments like finasteride and minoxidil, while others experience little to no improvement even with comprehensive treatment plans. Factors such as individual sensitivity to DHT may influence the effectiveness of these hair loss treatments.

community CRISPR treatment for AGA on the horizon after approval for blood disorders

in Treatment 10 upvotes 10 months ago

CRISPR treatments for blood disorders have been approved, leading to discussions about its potential for treating hair loss (AGA). A study showed that editing a gene related to DHT sensitivity could lead to hair regrowth, suggesting CRISPR may eventually be used for AGA, but it's expected to be expensive and not soon available.