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      The story of RU58841/ PSK3841

      community The story of RU58841/ PSK3841

      in Research  622 upvotes 6 months ago
      RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.

      community Discussion on Finasteride and life.

      in Chat  166 upvotes 4 months ago
      Finasteride can aid hair regrowth but may cause side effects like depression and sexual dysfunction. Users discuss experiences with finasteride, minoxidil, and RU58841, highlighting varied responses and the importance of informed treatment choices.

      community Best Ketoconozole shampoo that doesn’t dry out hair?

      in Ketoconazole  13 upvotes 3 months ago
      People are discussing ketoconazole shampoos that don't dry out hair, with suggestions including using it as a topical treatment, switching to T-Sal, and using moisturizing products like hyaluronic acid serum and biotin conditioner. Regenepure DR is confirmed to still contain ketoconazole, and some users recommend using moisturizing shampoos and conditioners to prevent dryness.

      community Finally Scalp Folliculitis-Free after 2 Decades of Suffering

      in Treatment  61 upvotes 4 months ago
      A 37-year-old male resolved scalp folliculitis by adopting a low-histamine diet and taking Vitamin A, Zinc, and Fish Oil, leading to better skin health and thicker hair. He warns about the potential toxicity of excessive Vitamin A intake.

      community Topical Dutasteride. Does it work?

      in Finasteride/Dutasteride  13 upvotes 9 months ago
      Topical dutasteride may be effective for hair loss by staying in the scalp and minimizing bloodstream absorption, potentially improving hair results and reducing side effects. The user seeks advice on its effectiveness.

      community Ru with gloves because of Systemic absorption?

      in Research/Science  10 upvotes 1 year ago
      The conversation is about whether to use gloves when applying 5% RU58841 to avoid systemic absorption and if washing hands with water is sufficient. Users question the concern, noting it is applied to the scalp.

      community Is the DHT itch fact or fiction?

      in Chat  16 upvotes 1 year ago
      DHT itch's existence is debated, with some claiming it's real and others saying it's psychological. Finasteride, Ketoconazole shampoo, and addressing scalp conditions like dandruff or eczema may help reduce itchiness.

      community My microneedling journey (no min, fin, etc)

      in Microneedling  210 upvotes 4 months ago
      The user experienced positive hair growth results using microneedling with rosemary and mint oil, without Minoxidil, Finasteride, or RU58841. They switched from a dermaroller to a microneedling pen and targeted different scalp areas weekly.

      community Why nobody uses 0.25% (2.5mg/ml)?

      in Treatment  66 upvotes 1 year ago
      The conversation is about the effectiveness of 0.25% topical finasteride compared to other concentrations and forms. Users discuss its potential for better scalp DHT reduction and fewer side effects, with some preferring topical over oral treatments.

      community A Complete Guide to Hair Loss for Beginners

      in Research/Science  530 upvotes 1 year ago
      The conversation is a guide on treating hair loss, discussing finasteride and dutasteride to lower DHT, minoxidil for growth, ketoconazole shampoo for scalp health, and dermarolling for regeneration. RU58841 is mentioned as a DHT blocker but not recommended due to safety concerns.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 2 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

      community My RU58841 Progress / Hair loss journey

      in Progress Pictures  71 upvotes 3 years ago
      A user shared their experience with hair loss treatments, including RU58841, ketoconazole shampoo, caffeine shampoo, and topical finasteride. They found RU58841 effective for diffuse thinning but experienced severe hair loss after stopping it; topical finasteride worked well for a receding hairline but caused side effects. They also use a charcoal shampoo and practice scalp massages.

      community How long have you tried topical melatonin?

      in Treatment  4 upvotes 11 months ago
      The conversation is about the effectiveness of topical melatonin for hair loss, asking for details on dosage, frequency, duration of use, results, and brand information. An update includes a skeptical view on the studies regarding melatonin's effectiveness.

      community What happened to topical dutasteride??

      in Finasteride/Dutasteride  28 upvotes 1 month ago
      Topical dutasteride is considered for hair loss, but concerns about systemic absorption and side effects like reduced libido are common. Users have mixed results, with some preferring oral finasteride or dutasteride despite side effects, while others find topical treatments beneficial but challenging.

      community i got more results 1 month 5 mg oral minoxidil and 1 mg dutasteride then i did 6 months on finasteride and topical minoxidil

      in Finasteride/Dutasteride  49 upvotes 1 year ago
      A user reported better hair regrowth with 5 mg oral minoxidil and 1 mg dutasteride than with finasteride and topical minoxidil, calling topical minoxidil a scam. Replies varied, with some defending topical minoxidil, questioning the user's application method, and suggesting that previous treatments might be contributing to the observed results.

      community Minoxidil alternative with a week long half-life? Why isn’t it possible?

      in Satire 2 years ago
      This conversation discussed the potential for a hair loss treatment alternative to minoxidil, with many users debating the economic and health implications of such an option. Some suggested that finasteride could be used as an alternative, while others argued that this would ultimately not benefit pharmaceutical companies due to their reliance on planned obsolescence.

      community Tretinoin can make it worse!!!

      in Chat  7 upvotes 1 year ago
      Tretinoin may enhance minoxidil's effectiveness for those not responding to minoxidil alone, but it could reduce efficacy for some who are already responding to minoxidil. Tretinoin requires careful use, including skin moisturizing and sun protection due to increased sensitivity.

      community Topical T3 study - 1000% Growth. Anyone tried it?

      in Research/Science  106 upvotes 3 years ago
      The conversation discusses using T3 (triiodothyronine) as a topical treatment for hair growth, with some users noting it showed promising results in studies but lacked follow-up. Users express interest in trying T3 due to its potential effectiveness compared to Minoxidil.

      community Topical Dutasteride is Here.

      in Finasteride/Dutasteride  153 upvotes 3 years ago
      The availability of Topical Dutasteride, a potential treatment for hair loss, which can be purchased without prescription from MinoxidilMax. Other treatments discussed include Topical Finasteride and PRP injections, with discussion around dosage, efficacy, side-effects and safety.

      community Has anyone used Magnesium L-Threonate ?

       74 upvotes 6 years ago
      Magnesium L-Threonate may help treat balding by reducing DKK-1 expression without affecting DHT. Users discuss its potential effectiveness and application methods, with some considering trying it topically.