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      community Will we ever hear about HMI -115

      in Update  20 upvotes 1 year ago
      Hair loss discussion includes treatments Minoxidil, Finasteride, and RU58841. Update on HMI-115 clinical trial expected in July or August.

      community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.

      in Research/Science  3 upvotes 3 weeks ago
      DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.

      community What happened to Breezula ????

      in Research/Science  9 upvotes 2 years ago
      The conversation discusses the effectiveness of a hair loss treatment called CB (Breezula) in comparison to Pyrilutamide, and its potential when combined with Finasteride. There is uncertainty about when or if phase 3 trials for Breezula will begin.

      community KX826 New Phase 3 Trial In China for 2025: 1.0% concentration

      in Research/Science  57 upvotes 1 month ago
      KX-826 is undergoing Phase III trials in China as a potential treatment for male pattern baldness, with some users considering it as an alternative or addition to finasteride and dutasteride. Opinions on its effectiveness vary, with some users reporting positive results and others finding it expensive and ineffective.

      community Melatonin emerging as new treatment for androgenic alopecia?

      in Update  37 upvotes 2 months ago
      Melatonin is being considered as a potential treatment for androgenic alopecia, with some users discussing its effects and combining it with other treatments like minoxidil and finasteride. Concerns about melatonin's impact on hormones and side effects from other treatments like ketoconazole were also discussed.

      community Dr. Gabel Doesn't Use Verteporfin

      in Transplants  3 upvotes 6 months ago
      Dr. Gabel doesn't use Verteporfin because it's not FDA approved. The user is getting FUT and wants to minimize scarring and maximize hair regrowth.

      community Hairloss Stack. Focused on density and Hairline

      in Progress Pictures  10 upvotes 7 months ago
      The user is using a combination of RU58841, Stemoxydine, RevivHair Serum, hair growth oil, topical Minoxidil, Alfatradiol, oral Minoxidil, and Finasteride to treat hair loss. They report no side effects from oral Minoxidil and Finasteride after 7 months of use.

      community 2nd day on pyrilutamide - what I noticed so far

      in Treatment  7 upvotes 2 years ago
      The user started using a hair loss treatment called pyrilutamide and experienced mild chest discomfort and tightness, similar to previous side effects from RU58841. They plan to reduce the dosage due to these side effects and will provide an update on the results in 1-2 months.

      community Why I deleted my YouTube channel Part I

      in Update  118 upvotes 3 years ago
      A YouTuber named Kevin, also known as Rider_Of_Roach, who deleted his YouTube channel due to personal attacks and controversy surrounding his views on hair loss treatments. He advocated for FDA-approved treatments like finasteride and minoxidil but faced backlash from those who disagreed with him. The conversation also discusses his past trolling behavior and a lawsuit he filed against a website that published false information about him. Despite some disagreements, many viewers appreciated his research-based content and hope to see him return in the future.

      community Replicel, worthy of hype or probable disappointment? Questions thread

       6 upvotes 8 years ago
      The conversation discusses the potential of Replicel/Shiseido treatment for hair loss, questioning its effectiveness, whether it grows new follicles, and its market release timeline. It also compares Replicel to other competitors like Kyocera/RIKEN/Tsuji.

      community Hydrophobic Finasteride. Why don’t we have it?

      in Chat  6 upvotes 4 weeks ago
      The conversation discusses the potential benefits of creating a hydrophobic version of finasteride to reduce systemic side effects while maintaining scalp health. It compares this idea to fluridil, which is designed to be hydrophobic and has less systemic absorption.

      community What to look Forward to in 2025

      in Research/Science  18 upvotes 1 month ago
      Hair loss treatments are advancing, with Coegin Pharma's FOL005 expected this year and Breezula potentially later. Pyrilutamide is available but not very effective, while Kintor's products face skepticism; traditional treatments like finasteride and minoxidil remain dominant.

      community What do you think about pyrilutamide?

      in Product  5 upvotes 1 month ago
      Pyrilutamide is being discussed as a potential hair loss treatment, but opinions are mixed, with some users skeptical about its effectiveness and the company's credibility. Some users report combining pyrilutamide with other treatments like dutasteride and microneedling, noting improvements, while others remain doubtful.

      community Being Safe on Oral Minoxidil: tl;dr on the literature.

      in Research/Science  48 upvotes 2 months ago
      Oral minoxidil is effective for hair loss but can cause cardiovascular side effects, such as pericardial effusion, especially in those with genetic predispositions. Starting with low doses and monitoring cardiovascular health are advised to reduce risks.

      community GT20029 & KX826 Major Updates from Kintor.

      in Research/Science  102 upvotes 3 months ago
      KX826 shows promise as a hair loss treatment with a 10% increase in hair count, but concerns about Kintor's marketing practices and the systemic effects of treatments like GT20029 and RU58841 remain. Users express skepticism and hope, with some preferring traditional treatments like finasteride and minoxidil.

      community Oral or topical finasteride? .

      in Chat  12 upvotes 6 months ago
      A user is deciding between oral and topical finasteride for hair loss, noting oral finasteride's ease of use but broader effects. Another user simply recommends oral finasteride.

      community Warning: Your Rogaine Foam Might Not Contain Minoxidil

      in Minoxidil  373 upvotes 8 months ago
      A user experienced significant hair loss after using Rogaine foam purchased from Amazon, which failed a bleach test for Minoxidil. They discovered that even legitimate Rogaine products might be faulty and advised buying from reputable sources.