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      community Why is dutasteride's volume of distribution so much bigger than finasteride? Is it more lipophilic and crosses barriers better?

       23 upvotes 1 year ago
      Dutasteride has a larger volume of distribution than finasteride due to its lipophilic nature, allowing it to concentrate in hydrophobic areas and making it difficult to excrete. A user experiencing hair loss has been using oral finasteride for 10 months with minimal regrowth and is considering switching to dutasteride or adding oral minoxidil.

      community Warning: Him's fraudulently reactivated subscription and refused to refund.

       212 upvotes 1 year ago
      Hims reactivated a subscription without consent, leading to unauthorized charges for Finasteride and Minoxidil products, and refused to issue a refund until a bank dispute was filed. Users discussed alternative, cheaper sources for these treatments and shared similar negative experiences with Hims.

      community Rob English's scalp massages, why aren't more people aren't talking about this?

      1 year ago
      Rob English's scalp massages are discussed as a method to reduce DHT and stop hair loss, but many users criticize it as ineffective compared to treatments like finasteride, dutasteride, and minoxidil. Some users argue that alternative treatments like scalp massages and microneedling can work for some, but the community largely favors the "big three" medications.

      community 3 month progress on 0.5mg fin only - I think it’s saving me.

      in Progress Pictures  77 upvotes 1 year ago
      A 23-year-old male shares his positive progress using 0.5mg finasteride for hair loss, noting initial side effects like sore nipples that resolved after adjusting the dosage. Other users discuss their experiences with finasteride, including effects on libido and the trade-offs of using the medication.

      community New hairline who's dis? Pics included

       491 upvotes 1 year ago
      The user shared positive progress in hair regrowth using dutasteride, topical minoxidil, and Keeps shampoo, with a unique minoxidil application schedule and glycolic acid exfoliation to maintain scalp health. They reported no side effects from dutasteride and are pleased with the results.

      community Anyone read oral minoxidil's leaflet?

       4 upvotes 1 year ago
      Oral minoxidil is discussed, highlighting potential cardiovascular risks at high doses, but users note that lower doses commonly used for hair loss are generally considered safe. Monitoring by doctors is advised, and some users report taking it without issues, comparing its risks to those of common medications like ibuprofen.

      community No idea what's causing my hair thinning

      in Chat  2 upvotes 1 year ago
      The user is experiencing diffuse hair thinning despite using finasteride and oral minoxidil, with no hairline recession or bald spots. Suggestions include checking for telogen effluvium, considering a JAK inhibitor for potential autoimmune issues, and conducting further tests to rule out other causes.

      community What is everyone's stack and why?

       21 upvotes 1 year ago
      People are using various treatments for hair loss, including dutasteride, finasteride, minoxidil (both oral and topical), RU58841, and ketoconazole shampoo. Some also use additional methods like microneedling, vitamins, and oils, with mixed results and personal preferences influencing their choices.

      community Does this mean it's finally working

      in Finasteride/Dutasteride  2 upvotes 2 years ago
      The user started using topical minoxidil in June 2023 and switched to a new finasteride preparation and vitamin D supplements a month ago. They noticed reduced hair shedding recently and are hopeful for regrowth.

      community Exploring Bryan Johnson's Hair Routine In Detail

       64 upvotes 2 years ago
      Bryan Johnson uses a custom hair loss treatment that includes topical finasteride, minoxidil, azelaic acid, diclofenac, tea tree oil, rosemary oil, ginkgo biloba, biotin, and melatonin, which have shown varying degrees of effectiveness with minimal side effects. He also undergoes PRP and laser therapy, and has tried dutasteride mesotherapy.

      community Rosemary oil's potency as a dht blocker

      in Research/Science  65 upvotes 2 years ago
      Rosemary extract showed high inhibitory activity against DHT, similar to finasteride and dutasteride, but the conversation includes skepticism about its effectiveness in humans since the study was done on mice and rosemary oil is often considered ineffective based on personal experiences. Some suggest trying rosemary oil alongside other treatments, while others emphasize the difference between the extract used in the study and the oil.

      community Peptides? Men's Journal article.

       9 upvotes 2 years ago
      The conversation is about the effectiveness of peptides for hair loss and the user considering using GHK-Cu, CJC-1295, and BPC-157 for treatment.

      community Minoxidil vs Redensyl, what’s better?

      in Minoxidil  1 upvotes 2 years ago
      The conversation discusses the differences between Minoxidil and Redensyl for hair loss treatment. It also questions why Redensyl isn't as commonly discussed despite claims of its effectiveness.

      community Anyone try Musely Men's Bloom Hair Pill?

       9 upvotes 3 years ago
      A user started taking Musely men's bloom hair pill, which contains minoxidil, dutasteride, and vitamins, and noticed a stop in hair shedding after switching from other hair loss treatments like hims and Keeps. They are questioning the effectiveness of the Musely pill due to its lower dosage of active ingredients and are curious about others' experiences with the product.

      community Bryan Johnson’s Hairloss Regimine

       27 upvotes 3 years ago
      The post is about Bryan Johnson's hair loss regimen, which includes dutasteride mesotherapy, minoxidil, microneedling, and red laser therapy. The conversation includes discussions about the effectiveness of topical dutasteride and speculation about whether Bryan Johnson has had a hair transplant.

      community Anyone here that's been using RU for 5+ years? [Serious]

       43 upvotes 3 years ago
      The conversation is about the long-term use of RU58841 for hair loss, with users sharing their experiences and seeking information on its effectiveness and whether it needs to be used continuously like minoxidil or finasteride.

      community Update from December's Pyrilutamide GB?

       13 upvotes 4 years ago
      Participants discussed hair loss treatments, specifically Pyrilutamide, with some experiencing side effects like heart palpitations and anxiety. There is uncertainty about the drug's effectiveness, and a new group buy is planned with a different lab due to concerns about purity.

      community My GF says it’s working. Oral min, Dut, niz, micro needling, RU

       36 upvotes 4 years ago
      The user reports positive results in hair thickness using a regimen of oral minoxidil, dutasteride, microneedling, RU58841, and mk677. They experienced minimal side effects, noting only temporary discomfort after starting dutasteride.