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      community The Cure isn't 5 years away; it's already here.

      in Research/Science  1005 upvotes 1 year ago
      PP405 is a new topical treatment for hair loss, showing promise in trials but still requires finasteride for maintenance. There is skepticism about its effectiveness and safety, with concerns about needing finasteride to maintain results.

      community Currently Trending Twitter Post: Clascoterone Hailed as New Cure

       1897 upvotes 9 months ago
      Clascoterone is being discussed as a promising new hair loss treatment, showing significant improvement in trials. Despite this, skepticism persists about its effectiveness, cost, and side effects, with some users preferring minoxidil and finasteride.

      community Hormonal changes on Finasteride?

       37 upvotes 1 year ago
      Finasteride can increase estrogen levels, causing dizziness and nausea. Users discuss adjusting treatment and diet, and explore alternatives for hair loss management.

      community Has anyone ordered JXL-069 (grey market PP405)?

       53 upvotes 1 year ago
      People are discussing JXL-069 (PP405) for hair loss, with some experimenting with a 0.05% topical gel. Concerns about safety and efficacy persist due to limited testing and lack of official approval.

      community Aminexil - does anyone us this?

       5 upvotes 4 years ago
      Aminexil is similar to Minoxidil but less effective and not widely used, with some users reporting minor regrowth. It is not FDA-approved and has been removed from some products, though some people still use it, often in combination with Minoxidil.

      community Getting PP405. Now…. or as soon as possible

       147 upvotes 1 year ago
      People are discussing obtaining and testing PP405 for hair loss treatment, with concerns about its purity and effectiveness. Some are considering delaying hair transplants, while others suggest using existing treatments like finasteride and minoxidil.

      community I’m considering stopping finasteride

      in Finasteride/Dutasteride  157 upvotes 8 months ago
      The user is considering stopping finasteride due to depression, anxiety, and difficulty building muscle, despite its effectiveness in stopping hair loss. Suggestions include reducing the dose, switching to topical solutions, or consulting a doctor for alternatives like dutasteride or RU58841.

      community Hair regrowth attempt. Age 33 after 10 years bald.

       650 upvotes 6 months ago
      A 33-year-old attempted hair regrowth after 10 years of baldness using topical finasteride, minoxidil, micro-needling, a laser cap, and later oral dutasteride. They noticed some regrowth, especially vellus hairs, and are considering a hair transplant or other treatments despite side effects.

      community My DHT levels while being on DUT for a year

      in Finasteride/Dutasteride  33 upvotes 1 year ago
      The conversation discusses the ineffectiveness of tablet forms of dutasteride for hair loss due to poor absorption compared to soft gel capsules. It suggests switching to FDA-approved soft gel capsules for better results, as tablets may not adequately suppress DHT levels.

      community How much better is dut compared to fin?

      in Chat  35 upvotes 1 year ago
      Dutasteride is often more effective than finasteride for blocking DHT, but results vary and some may experience side effects. Combining minoxidil with either medication can improve hair regrowth, but switching doesn't guarantee better results for everyone.

      community Finasteride and fertility. Personal report.

      in Finasteride/Dutasteride  829 upvotes 1 year ago
      Finasteride can affect sperm quality, but fertility usually returns after stopping it, as shown by a user who conceived four months after discontinuation. Some users successfully conceive while on finasteride, though some prefer to pause its use to minimize risks.

      community hair loss treatment myths that perplex me

       7 upvotes 1 year ago
      Grapefruit juice doesn't significantly affect finasteride or dutasteride. Drinking topical minoxidil is risky; saw palmetto is less effective than finasteride or dutasteride for hair loss.

      community What's the deal with Spectral.DNC-N/'nanoxidil'?

       4 upvotes 4 years ago
      Nanoxidil is considered to have better absorption and fewer side effects than minoxidil, with added DHT blockers. The user is questioning if switching to the more expensive Spectral.DNC-N is worthwhile compared to cheaper options like Kirkland minoxidil.

      community Minokem-N cotains hydrocortisone?

       2 upvotes 1 year ago
      Minokem-N's composition is unclear, with concerns about unlisted hydrocortisone. Users discuss alternatives like AloATM, which lacks soothing agents, and the challenges of verifying ingredients.

      community Let Me Sell You on NAC

       17 upvotes 7 years ago
      The conversation discusses using NAC (N-Acetyl Cysteine) alongside minoxidil and finasteride for hair loss, with some users noting potential hairline improvement and increased energy. The original poster reduced their finasteride dosage due to mental decline and anxiety, and while NAC's effects on hair are anecdotal, it is considered low-risk with other health benefits.

      community Celebrity hair transplants- Akshay Kumar's HT analysis

      in Transplants  12 upvotes 1 year ago
      Akshay Kumar's hair restoration appears conservative, likely involving a small-session FUE hair transplant or non-surgical treatments like PRP, with subtle improvements in density and frontal framing. The overall success is rated 3.5/5, with ongoing maintenance suggested for longevity.

      community Cbum's hair transplant looks absolutely terrible

       979 upvotes 1 year ago
      A bodybuilder's hair transplant appears unnatural with a straight hairline and low density, possibly worsened by not using finasteride. The Turkish clinic is criticized for poor design, and the transplant may have been free for promotion.

      community Can be this a new game changer? What's your Opinion about it

       528 upvotes 10 months ago
      The conversation discusses skepticism about new hair loss treatments, with many users expressing doubt about their effectiveness compared to existing treatments like minoxidil and finasteride. Some users mention natural oils like olive and macadamia oil, but overall, there's a consensus that these are unlikely to be game changers.

      community Exploring Bryan Johnson's Hair Routine In Detail

       64 upvotes 2 years ago
      Bryan Johnson uses a custom hair loss treatment that includes topical finasteride, minoxidil, azelaic acid, diclofenac, tea tree oil, rosemary oil, ginkgo biloba, biotin, and melatonin, which have shown varying degrees of effectiveness with minimal side effects. He also undergoes PRP and laser therapy, and has tried dutasteride mesotherapy.