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GlossarySildenafil (Revatio)

medication used to treat erectile dysfunction and pulmonary hypertension

Sildenafil is a medication primarily used to treat erectile dysfunction and pulmonary arterial hypertension. It works by inhibiting an enzyme called phosphodiesterase type 5 (PDE5), which leads to the relaxation of blood vessels and increased blood flow to specific areas of the body. Commonly known by its brand name Viagra when used for erectile dysfunction, it is also marketed as Revatio for treating pulmonary arterial hypertension.

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community No, Finasteride as a treatment for MPB was not an "accident"

in Research/Science 105 upvotes 3 years ago

Finasteride was intentionally developed to treat BPH and later approved for male pattern baldness (MPB) due to its 5AR inhibition effects. The delay in MPB approval was due to concerns about off-label use for female hirsutism and the prioritization of treating a more debilitating condition.

community Table of the relationship between physical exercise and the regeneration of the deminiaturized hair follicle

in Research/Science 44 upvotes 1 month ago

Exercise, especially leg workouts, combined with finasteride and minoxidil, may enhance hair regrowth. Cold exposure, like cold showers, might further boost results.

community What's the exact relation with green tea and dht?

in Chat 9 upvotes 6 months ago

The conversation is about the effects of green tea on DHT levels and its impact on hair loss. It concludes that natural remedies like green tea are less effective than hair loss drugs such as Minoxidil, finasteride, and RU58841.

community Kintor has released an investor relations memo regarding Chinese Phase III trials for Pyrilutamide

in Update 53 upvotes 11 months ago

Kintor's Pyrilutamide (KX-826) showed hair growth in Chinese Phase III trials but did not significantly outperform placebo. The treatment was safe with no major adverse reactions reported.

community Hmi-115 hair loss cure, how does it work? Is there a relationship between prolactin and DHT?

in Research/Science 7 upvotes 1 year ago

Hair loss linked to DHT and prolactin levels. Hmi-115 cure discussed, along with Minoxidil, Finasteride, and RU58841 treatments.

community 8 Month Progress (topical min 8x daily, 1mg fin daily, 8mm microneedling daily, 11 drops of demon blood 4x a week, 8mg oral min daily, crying in the mirror 4x daily, blaming my thinning hair for all my relationship problems once a week) Don’t give up, you can do it 💪

in Satire 106 upvotes 6 months ago

The post humorously discusses an exaggerated hair loss treatment regimen including minoxidil, finasteride, microneedling, and "demon blood." Replies joke about the regimen and suggest alternative sources for "demon blood."

community Blood DHT Levels – before and after creatine

in Research/Science 41 upvotes 1 year ago

The impact of creatine on DHT levels, and whether it could cause accelerated male pattern baldness (MPB). The user taking a 5 alpha reductase inhibitor found that their DHT levels actually reduced despite taking creatine for nine weeks. Replies suggested looking into testosterone levels as well and debating the safety of creatine use in relation to MPB.

community Dermatologist told me to quit fin after turning 40

in Finasteride/Dutasteride 194 upvotes 1 year ago

A dermatologist advised a patient to stop taking finasteride (fin) after turning 40 due to potential risk of aggressive prostate cancer. The patient and others in the conversation debated this advice, discussing the relationship between finasteride, prostate cancer, and hair loss, and considering alternatives like topical finasteride.

community microinflammation caused by mometasone furoate?

in Research/Science 2 upvotes 1 year ago

The user experienced microinflammation on the crown after using mometasone furoate (Nasonex) nasal spray. They are seeking information on the relationship between this corticosteroid and hair loss.

community Boys, ALWAYS do your due diligence before going the hair transplant route!

in Transplants 641 upvotes 1 year ago

A user's experiences with hair loss treatments, including finasteride and hair transplants, in relation to another person who has been publicly vocal about their own hair loss struggles. People have shared opinions on this other person's treatment choices and the results of their hair transplant.

community This is what Six years of DUT looks like

in Finasteride/Dutasteride 784 upvotes 1 year ago

User had success with dutasteride for hair loss after finasteride didn't work. Some experienced increased cholesterol and debated its relation to DHT.

community Cigarette smokers had increased serum levels of DHT 14% higher than non smokers.

in Chat 82 upvotes 1 year ago

The effects of smoking cigarettes on DHT levels and its potential effect on hair loss, with some people sharing experiences in relation to their own hair loss. Various treatments for reducing or reversing hair loss were discussed, such as quitting smoking, minoxidil, finasteride and RU58841.

community What you look like 2 years after scalp micropigmentation

in SMP 195 upvotes 2 years ago

Scalp micropigmentation as a treatment for hair loss, and the importance of choosing a reputable practitioner to get a natural look. Different treatments such as laser removal were also discussed in relation to long-term maintenance.

community Got Blood Work Lab Results for hormones. Need some help analyzing hormone values for Fin

in Finasteride/Dutasteride 7 upvotes 2 years ago

The user got blood work to check hormone levels before starting Finasteride for hair loss and is seeking advice on interpreting the results. They are considering hormone levels in relation to potential side effects of Finasteride.

community Finasteride changes my life , I never grow ever before so much hair

in Update 190 upvotes 3 years ago

User experienced hair regrowth after 6 months on finasteride and 3 months using keto shampoo, with no side effects. Others shared their experiences and gave advice on relationships and hair care.

community Bloodwork post finasteride gyno sides

in Finasteride/Dutasteride 8 upvotes 3 years ago

The user stopped using finasteride after two weeks due to gynecomastia symptoms and shared blood work results questioning if they indicate a cause for the side effects. The user is considering restarting finasteride and seeking advice on their blood work levels in relation to gynecomastia.

community Started going bald at 21, I’m 32 Now and Decided to Try a Hair Piece.

in Hair Systems 675 upvotes 3 years ago

A user who has started to go bald and decided to try wearing a hair piece, discussing the experience of doing so and sharing tips for maintenance. The conversation includes discussion about confidence in relation to wearing a wig or hair piece, as well as advice on getting it cut and attached professionally.

community Question about topical part of treatment

in Treatment 2 upvotes 5 months ago

The user is using a combination of oral Dutasteride and Minoxidil, and a topical formula with Finasteride, Minoxidil, and Hydrocortisone, along with rosemary oil, coconut oil, ginseng, and a derma roller. They are also using LLLT therapy and are questioning the timing of the laser cap session in relation to the topical application.

community Does lowering serum prolactin lower prolactin in the scalp?

in Research/Science 13 upvotes 9 months ago

The conversation discusses whether not masturbating (semen retention) affects hair loss, with opinions varying but generally dismissing the idea. Some participants mention using hair loss treatments like Minoxidil, Finasteride, and RU58841, but the effectiveness and relation to prolactin levels in the scalp are debated.

community Losing hair as teenager Dont know what to do

in Chat 3 upvotes 1 year ago

A teenager started balding at 13 and has been using minoxidil for 2 years, but the hair loss is returning. They are seeking advice on additional treatments. Another user suggests finasteride or shaving the head, and emphasizes the importance of not letting hair loss affect self-esteem and relationships.

community Kintors interim report from 9-2-24 for everyone whos interested

in Product 32 upvotes 2 months ago

Kintor plans to release pyrilutamide foam and a plant-based Koshine by year-end, with GT20029 progressing in their pipeline. Users are pleased about the absence of propylene glycol (PG) in the new products.

community Some of y’all need to hear this

in Chat 351 upvotes 2 years ago

Understanding that the importance of hair loss should not be overstated and encouraging self-love and confidence regardless of physical appearance. People discussed how they were feeling about their own hair loss and shared tips on treatments like Minoxidil, Finasteride and RU58841.

community Why balding gets worse in every generation?

in Chat 81 upvotes 5 months ago

Balding seems to worsen with each generation, possibly due to stress, diet, and environmental factors. The user started treatments like Minoxidil and finasteride.

community Can’t tolerate oral fin at any dosage, help me brainstorm a treatment plan.

in Treatment 9 upvotes 6 months ago

The user cannot tolerate oral finasteride and is considering topical finasteride, minoxidil, microneedling, and RU58841 as alternative treatments for hair loss. They seek advice on whether these options are worth trying.

community We all regret not acting on hair loss sooner. What is something else we can prevent if we act now?

in Chat 94 upvotes 11 months ago

The conversation discusses the importance of early action in various aspects of life such as healthy eating, skincare, fitness, sleep, financial planning, and career development to prevent future health issues, regret, and financial hardship. Specific treatments mentioned include using sunscreen and tretinoin for anti-aging skincare.

community New Latanoprost-Based Formula Used by Hollywood Celebrities

in Treatment 25 upvotes 1 year ago

A new Latanoprost-based formula used by Hollywood celebrities to treat hair loss, with the formula containing minoxidil, tretinoin, melatonin, azelaic acid, zinc thymulin, vitamin B6, sandalore and methyl vanillate. It also mentions the potential of offering a combined sublingual minoxidil/oral dutasteride option in the future.

community Is itching related to hair loss?

in Treatment 54 upvotes 2 years ago

Hair loss, which is sometimes accompanied by itching. Treatments discussed include Minoxidil, finasteride, RU58841 and ketocazole shampoo.

community Adrogens and Covid-19

in Treatment 8 upvotes 4 years ago

The possible increased risk of severe Covid-19 cases in men due to higher androgen levels, and how taking medications such as finasteride, dutasteride, spironolactone, enzalutamide, or canabidiol might help mitigate the severity of the disease.

community What Hinders the Absorption of Minoxidil?

in Minoxidil 1 upvotes 2 weeks ago

Silicone and dimethicone in shampoos may hinder Minoxidil absorption, while Tretinoin and microneedling can enhance its efficacy. Users discuss applying Tretinoin before Minoxidil, waiting for it to dry first.

community Since Dutasteride is dose dependent, is there any real difference in taking 0.5mg daily vs every other day?

in Finasteride/Dutasteride 16 upvotes 3 weeks ago

Taking dutasteride daily at higher doses results in more effective DHT suppression compared to every other day dosing, due to its dose-dependent nature and long half-life. Even at lower doses, dutasteride is more effective than finasteride for hair loss.