Dutasteride significantly reduces scalp DHT levels and can save hair, though shedding is part of the process. Some users report success with dutasteride, while others struggle despite using it along with finasteride and oral minoxidil.
A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.
Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.
The conversation discusses preferences for hair loss treatments, specifically finasteride over dutasteride. Users share personal experiences, cost considerations, FDA approval status, and potential side effects, with some switching between treatments to find what works best for them.
Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.
Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.
Tretinoin can make minoxidil more effective for hair loss treatment, but some users did not see improved hair density with this combination and had better results with dutasteride.
A new product, a retinoicacid solution (0.3%), is available to enhance minoxidil products like Rogaine and Kirkland by converting them into a tretinoin-containing solution for improved hair loss treatment. One unit of the product is enough for a year's supply.
The user has been using Minoxidil and finasteride with success and is now trying Dualgen-5R with retinoicacid but without finasteride, along with microneedling. They plan to share results in 5-6 months.
The user experienced hair shedding and follicle shrinkage when using retinoicacid, despite trying different concentrations and frequencies. The hair loss persisted for six months but regrew after stopping the treatment.
A user is making a 2-Deoxy-D-ribose solution and asks if it can be put into an oil instead of a gel, considering adding hydrocortisone and retinoicacid. They seek advice on the best carrier oil for hair growth.
The user is using a topical solution with finasteride, minoxidil, and retinoicacid, which causes scalp residue and dryness. They seek advice on removing residue and keeping the scalp moisturized.
A user shared their 4-month progress using a serum with Minoxidil 10%, Progesterone, Azelaic acid, Retinoicacid, Latanoprost, and Hydrocortisone, along with PRP and Fotona laser treatments. They are pleased with the results and plan to continue with more PRP and laser sessions, without using Finasteride.
The conversation discusses hair loss treatments, specifically an $80/month product containing Minoxidil, Finasteride, RetinoicAcid, and Hydrocortisone with an aloe base. One reply suggests cheaper alternatives like generic oral Finasteride and liquid Minoxidil from Costco.
The user is considering switching from an expensive topical hair loss treatment containing 8% Minoxidil, 0.3% Finasteride, RetinoicAcid, and Hydrocortisone to a cheaper Kirkland brand Minoxidil. They are concerned about the effectiveness of the lower concentration and the absence of additional ingredients.
The post discusses the high cost of a topical hair loss treatment from Happy Head, which contains finasteride, minoxidil, retinoicacid, and hydrocortisone. The user is seeking cheaper alternatives, specifically asking if there are compounding pharmacies that can recreate the same or similar formulation.
A user sought treatment for hair loss through Cortina Health, where they were prescribed a specific topical solution containing Finasteride, Minoxidil, and RetinoicAcid. They are unsure if this unique combination is better than generic products and are seeking advice on whether to trust Cortina Health.
A user's progress with treating their hair loss, including using finasteride, minoxidil, retinoicacid, dermapenning twice weekly and ket 2% shampoo two to three times per week. Other users offered advice such as not derma penning too often or shaving the area bald for a couple of months.
The conversation is about using Maxogen-X for hair loss, which contains Minoxidil, Finasteride, Azelaic Acid, ABN Complex, RetinoicAcid, Fluocinolone, and Caffeine. The user is seeking feedback on its effectiveness.
The user is considering two hair loss treatments: Minoxidilmax Maxogen-x, which contains Minoxidil, Finasteride, Azelaic Acid, ABN Complex, RetinoicAcid, Fluocinolone, and Caffeine, and Morr-F, which contains only Minoxidil and Finasteride. They are asking for others' experiences with these brands.
The conversation discusses using dutasteride, both topical and oral, for hair loss in trans men, considering potential side effects like depression and libido issues. The user is exploring options including topical solutions with minoxidil, retinoicacid, and hydrocortisone, and plans to start microneedling.
A 31-year-old who experienced severe hair loss during medical school tried various treatments, including topical and oral finasteride and minoxidil, but stopped due to side effects. They restarted treatment 10 months ago with a regimen including topical finasteride, minoxidil, retinoicacid, hydrocortisone, oral minoxidil, and light therapy, emphasizing the importance of consistency and skincare.
The conversation discusses a hair loss product containing Minoxidil, Finasteride, Azelaic Acid, and Caffeine. People are sharing their experiences and reviews of the product.
The conversation discusses using a combination of finasteride, spironolactone, minoxidil, retinol, azelaic acid, and caffeine for hair loss treatment. The user inquires about the limitations of these drugs and whether tretinoin would be more effective than retinol.
Retinol or tretinoin may improve minoxidil absorption and effectiveness. The user is considering using The Ordinary's 1% retinol as tretinoin is hard to get in their country.
Tretinoin may increase minoxidil absorption but could potentially worsen hair loss over time. Users discuss applying 0.5% tretinoin gel to the hairline/scalp with minoxidil.
A 59-year-old male switched to a once-daily treatment of 7% Minoxidil, 0.15% Finasteride, and other ingredients, questioning its effectiveness compared to his previous twice-daily regimen. He has seen some hair regrowth but is unsure if the new treatment is better.
The user is using a solution of Finasteride, Minoxidil, and Tretinoin, which increases Minoxidil's effectiveness. They are seeking a reliable source of Tretinoin to add to over-the-counter Minoxidil solutions.
