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Topical spironolactone 5% is being discussed for its effectiveness in treating hair loss, specifically receding temples. The user is inquiring if it works similarly to finasteride as a testosterone blocker.

User experienced new hair growth after using Head and Shoulders 2-in-1 shampoo/conditioner, attributing it to pyrithione zinc reducing scalp inflammation and DHT. They seek others' experiences with anti-dandruff products.

Dutasteride at 0.5 mg/day does not significantly alter allopregnanolone levels, but higher doses (2.5 mg/day) do. Dutasteride may also have anti-neuroinflammatory effects, but the impact on neurosteroids is still debated.

Melatonin is being discussed as a potential treatment for hair loss, with questions about its effectiveness and whether it should be used topically or orally. No specific conclusions or personal experiences were shared.

The conversation discusses hair loss treatments, specifically Minoxidil, finasteride, and RU58841. The user inquires if RENU Biogen is a DHT inhibitor.

The conversation discusses hair loss treatments, with users mentioning dutasteride (Dut) as effective and wishing for more accessible dosages. They also debate the components of the "big 3" treatments, which now include Dut, RU58841, and oral minoxidil, with finasteride and minoxidil being consistently mentioned.

A user started taking finasteride three months ago to treat hair loss and unexpectedly cleared their acne, which they had been struggling with since age 12. The conversation includes others sharing their experiences with finasteride, its effects on acne and hair loss, and mentions a related treatment, clascoterone, for acne and hair loss.

The conversation discusses seeking a stronger treatment than Dutasteride (DUT) for hair loss. Suggestions include combining DUT with RU58841, increasing DUT dosage, and using transgender hormone replacement therapy or testosterone blockers, though some options may have feminizing side effects.

A user experienced severe chest pains and shortness of breath after using RU58841 for hair loss and was advised by a doctor that blocking androgens can weaken the heart. They decided to continue with finasteride, minoxidil, and a hair transplant instead.

The conversation is about a user's hair regrowth after 2.5 months using topical minoxidil. Some suggest adding finasteride for long-term results, while others share their experiences with side effects or alternative treatments like dermarolling and dietary improvements.

Testosterone within the normal range does not significantly contribute to male pattern baldness (MPB); DHT is the main factor that can be controlled. Genetics play a crucial role in hair loss, and treatments like finasteride and dutasteride, which block DHT, can help despite potentially raising testosterone levels.

The conversation discusses hair loss linked to BDNF-increasing nootropics like Semax and Lions Mane. Suggested topical treatments include capsaicin, beta-glucan, and ginseng to counteract TGF-B activation.

The discussion revolves around the need for future oral DHT blockers for hair loss treatment that don't have the side effects of current options like Finasteride and Dutasteride. One user suggests that the future of hair loss treatment will likely be topical anti-androgens, as they can target hair follicles without affecting the entire system.

The user has been using 1mg finasteride every other day, 5% minoxidil daily, and microneedling every two weeks for three months to treat hair loss. They are happy with the progress and considering adding ketoconazole shampoo to their routine.

The conversation is about the effectiveness of RU58841 for hair loss. People are discussing how long it took to see results from using RU58841.

The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.

The conclusion of the conversation is that the user, General-Switch-5722, has been using finasteride and minoxidil for over 2 years but is still experiencing hair loss. They are considering adding a low dose of RU58841 or topical dutasteride as potential treatments. Other users in the conversation have suggested switching to dutasteride or using oral minoxidil.

The conversation discusses adding melatonin powder to a topical finasteride solution for hair loss, with one reply suggesting that melatonin may promote faster hair growth but advising against mixing it directly into the solution due to potential instability.

Isotretinoin may cause hair loss by increasing DHT through a precursor androgen, DHEAS. Treatments like topical antiandrogens (RU58841, pyrilutamide) and drugs increasing PPAR-y expression (pioglitazone) might prevent this hair loss.

The conversation is about a person's hair loss treatment regimen, which includes Minoxidil, low-dose Finasteride, Pyrilutamide, weekly use of a derma roller, and hair loss shampoo. They chose these treatments to minimize systemic effects and plan to share their results for others' benefit.

A user shared a six-month update on hair improvement using Pyrilutamide and Minoxidil, noting significant hair regrowth and strength. Some participants questioned the legitimacy of the results and the source of Pyrilutamide.

The user is seeking advice on which treatment to add to their current regimen for male pattern baldness. They have previously tried Dutasteride, Nizoral, and oral Minoxidil, but experienced continued hair loss. They are specifically asking for experiences with RU58841, Stemoxydine, or Alfatradiol.

RU58841 combined with finasteride or dutasteride is more effective than RU58841 alone for hair loss. Users suggest combining these with minoxidil and microneedling for better results.

User tried Dutasteride 0.5 mg twice a week and topical minoxidil for 3 months for hair loss. They are happy with the results.

User considers trying Pyrilutamide for hair loss and itch relief. Another user shares positive experience with Pyrilutamide, no side effects.

User started minoxidil topical 3 months ago for beard and hairline growth. Considering adding nizoral and microneedling for better results.

User on finasteride for a decade and oral minoxidil for a month asks about Nizoral shampoo's effectiveness and usage. Dermatologist suggests it may help with seborrheic dermatitis and hair loss, but not necessary; others share mixed opinions.

Combining Finasteride with topical Quercetin, Onion/Garlic juice and Peppermint Oil to reduce Wet Prostate Weight in Rats. Luke10191 asked the user LITUATUI to update them on progress after trying this combination of treatments for hair loss.

Maximum serum DHT suppression for finasteride occurs at 8 hours, while for dutasteride, it occurs within 1 to 2 weeks with daily dosing. Dutasteride mesotherapy will be followed by blood tests to check serum DHT changes.

User suggests a DIY zix formula for hair loss treatment and shares personal success with it. Another user disagrees, calling zix a "snake oil potion" and advises finding a real treatment instead.