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      community Microneedling only with rosemary

      in Microneedling 7 months ago
      A user asked if microneedling, massages, and essential oils can prevent further hair loss in the crown area without using drugs. The response indicated that without a 5-alpha-reductase inhibitor, hair loss will likely continue.

      community Mechanism of action of alfatradiol (17 alpha estradiol)

      in Research/Science  6 upvotes 7 months ago
      The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.

      community M28, Surprising 20 day progress

      in Progress Pictures  6 upvotes 7 months ago
      A 28-year-old shared surprising hair regrowth progress after 20 days using topical minoxidil, micro needling, GHK-cu, and BPC-157 injections. The user noted a significant reduction in their bald spot and overall hair improvement.
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      community Topical fin+minox deadly combo. M30 gave up and came back from dead.

      in Progress Pictures  14 upvotes 9 months ago
      A user reported hair regrowth using a homemade topical solution of minoxidil and finasteride sourced from Pakistan, combined with microneedling, after experiencing hair loss with UK-based products. They claim a reduction in hair loss from 200-300 to 3-5 hairs a day and advise against spending money on branded products.

      community Lowering DHT vs measured level and topical scalp treatment issues

      in Research/Science  1 upvotes 10 months ago
      The conversation discusses the effects of lowering DHT on hair loss and the importance of monitoring DHT levels during treatment. The user suggests that individual responses to DHT and hair loss treatments vary, and expresses a preference for topical treatments over oral medications due to concerns about systemic DHT reduction.

      community 2.5mg dut safety/price/synergy w/topical fin

      in Finasteride/Dutasteride  3 upvotes 10 months ago
      The conversation discusses the safety and cost of 2.5mg Dutasteride, and the potential for increased DHT reduction by combining Dutasteride with topical Finasteride. The original poster is currently using 0.5mg Dutasteride, 1.25mg oral Minoxidil, and a topical treatment, and is considering increasing the dosage to maximize results while avoiding less known treatments like RU58841.

      community Finasteride increase in Estradiol?

      in Update  17 upvotes 11 months ago
      A user experienced increased estradiol, nipple tenderness, and ED after taking finasteride. They are considering dose reduction to mitigate these effects.
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      community 2 month progress with Minoxidil and Dermaroller

      in Minoxidil  412 upvotes 11 months ago
      The conversation discusses a user's two-month hair regrowth progress using Minoxidil and a 0.5mm dermaroller. Some suggest adding a 5-alpha-reductase inhibitor like finasteride or dutasteride to maintain the results.

      community Approximation of Scalp DHT Suppression Between 0.05 mg to 2.5 mg

      in Research/Science  63 upvotes 11 months ago
      The conversation discusses the effectiveness of various doses of Dutasteride in reducing scalp DHT and its impact on hair count. Users shared personal experiences with hair loss treatments, including Dutasteride, Finasteride, and Minoxidil, with one reporting significant hair loss reduction using a combination of oral Dutasteride and topical Minoxidil and Finasteride.

      community Why nobody uses 0.25% (2.5mg/ml)?

      in Treatment  66 upvotes 1 year ago
      The conversation is about the effectiveness of 0.25% topical finasteride compared to other concentrations and forms. Users discuss its potential for better scalp DHT reduction and fewer side effects, with some preferring topical over oral treatments.

      community 8 week - sharing Finasteride blood test update

      in Progress Pictures  6 upvotes 1 year ago
      A 32-year-old male started taking 0.5mg of finasteride daily for hair thinning and, after 8 weeks, experienced a 70% reduction in DHT and an increase in estradiol; he is currently in the shedding phase of treatment and questioning if the dosage is correct based on his DHT levels. He began with a lower dose due to already low normal testosterone and DHT levels.

      community NW5 at 19. How many grafts do I need?

      in Transplants  140 upvotes 1 year ago
      A 19-year-old with rapid hair loss since 16 is considering a hair transplant but refuses to take finasteride or any 5α-Reductase inhibitors. They are currently using minoxidil, tretinoin, and microneedling with a Derminator 2, and only want hair until age 27.

      community Surprisingly thorough study on He-Shou-Wu/Fo Ti

      in Research/Science  14 upvotes 1 year ago
      He Shou Wu (Fo Ti) extract was found to prolong the hair growth phase, inhibit 5-alpha-reductase (like finasteride), reduce androgen receptors, and increase growth factors, potentially outperforming minoxidil in recovering hair follicle size after DHT exposure. Two compounds, emodin and TSG, are identified as responsible for these effects and warrant further investigation.

      community An idea that I came up with recently💡

      in Satire  289 upvotes 1 year ago
      User suggests rotating scalp 180 degrees to address hair loss. Others discuss sanity, ethics, and similar procedures like scalp reduction and hair transplants.

      community Blood DHT Levels – before and after creatine

      in Research/Science  41 upvotes 1 year ago
      The impact of creatine on DHT levels, and whether it could cause accelerated male pattern baldness (MPB). The user taking a 5 alpha reductase inhibitor found that their DHT levels actually reduced despite taking creatine for nine weeks. Replies suggested looking into testosterone levels as well and debating the safety of creatine use in relation to MPB.

      community Why are low finasteride doses seen as highly ineffective, when studies show 0.05 mg/day to work?

      in Finasteride/Dutasteride  38 upvotes 2 years ago
      The efficacy of low doses of finasteride to reduce scalp DHT, and whether studies showing a 61% reduction are reflected in actual results. Replies discussed hair growth as an unintended consequence of minoxidil and finasteride use, as well as self-selective bias, potential side effects, and that studies measure effectiveness by hair count changes rather than DHT inhibition.

      community Thoughts on Pantostin Alfatradiol?

      in Treatment  10 upvotes 3 years ago
      User started using Pantostin Alfatradiol after watching haircafe on YouTube and noticed thicker hair. They wonder why it's not more popular, as it's a 5α-reductase inhibitor with a different mechanism than minoxidil.

      community What should I expect from dutasteride?

      in Finasteride/Dutasteride  2 upvotes 3 years ago
      The user tried Minoxidil, PRP, Hair Carboxytherapy, and topical Dutasteride with limited success and is now on oral Dutasteride. They are experiencing some hair loss reduction but no significant density improvement, leading to feelings of depression.

      community Finasteride 1 Month Update

      in Finasteride/Dutasteride  17 upvotes 3 years ago
      User reports using 0.5mg finasteride, 12.5mg zinc daily, and keto shampoo weekly for hair loss. After one month, there's a slight reduction in hair shedding and no side effects.

      community I've been using Topical Finasteride for a few months[UPDATE]

      in Update  6 upvotes 4 years ago
      Graduate08 has been using topical finasteride since August 2020 to treat hair loss, initially every other day and now daily, with no significant side effects and some reduction in hair fall. They plan to continue this treatment and may add minoxidil if their condition worsens.

      community After 1.5 years+ on dut/fin hairless has finally slowed!

      in Finasteride/Dutasteride  76 upvotes 4 years ago
      After 1.5 years on finasteride and dutasteride with continued hair loss, the user noticed a significant reduction in hair shedding, attributing it to the consistent use of finasteride, along with a no-shampoo approach, multivitamins, vitamin D, and restarting minoxidil. Other users shared their happiness for the improvement and noted that hair loss can fluctuate naturally over time.

      community 8.5 fin progress!

      in Update  56 upvotes 5 years ago
      The user reported significant hair regrowth after 8.5 months using Minoxidil, Finasteride, and initially Biotin, with a 50% reduction in the balding crown area. They are considering either a hair transplant for further improvement or embracing a bald look, feeling confident they could pull it off.

      community 1 Year Progress: Rogaine + Finasteride

       8 upvotes 10 years ago
      A user shared their one-year progress using Rogaine (Minoxidil) and Finasteride for hair loss, noting some regrowth and a reduction in hair loss progression. They apply Rogaine twice daily, take a quarter tablet of Finasteride nightly, occasionally use Ketoconazole shampoo, and have not experienced severe side effects.