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The conversation is about using another shampoo after Nizoral to improve hair appearance without reducing ketoconazole's efficacy. Users also discuss adding coconut oil to Nizoral to prevent hair dryness.

Botox injections may be more effective than finasteride for hair growth by reducing scalp tension. The discussion also suggests choosing FUE over FUT due to potential loss of scalp elasticity with FUT.

The user increased their steroid dosage and noticed hair shedding, so they adjusted their regimen by reducing steroid doses and adding oral dutasteride. They are also experimenting with combining RU-58841 and KX-826/pyrilutamide in minoxidil to address hair loss.

A $3 hair oil applicator is recommended for applying minoxidil efficiently, reducing wastage and oily scalp issues. Users discuss cleaning methods and price differences.

Topical finasteride results in plasma levels 100 times lower than oral finasteride, potentially reducing systemic side effects. Users report similar efficacy with fewer side effects, suggesting a preference for topical application.

A 31-year-old male used topical finasteride for a year, reducing hair loss significantly with no side effects. Another user suggested adding minoxidil and using oils for better results.

A 21-year-old used 1.25mg finasteride and minoxidil twice daily for hair regrowth, reducing finasteride to 5 times a week since September. He also started using Nizoral for dandruff, noticed an increased appetite, and experienced a temporary change in sex drive.

Hair loss treatment using minoxidil and finasteride, with the user experiencing a shed after reducing the frequency of application and stopping microneedling. The user is now waiting for new hair growth and hoping to see similar results as before.

The user has been using finasteride for a year and minoxidil for 1.4 years, recently reducing the finasteride dose due to side effects. They also use vitamin D3 and ketoconazole shampoo, noting less hair shedding.

User GreatCanuck experienced hair regrowth after using finasteride for a year, reducing anxiety about hair loss. Others in the conversation shared similar positive experiences and discussed family members using the treatment.

The user reports improved hair growth after adding oral minoxidil and microneedling to their routine, while reducing oral minoxidil dosage due to hand swelling. They've been treating hair loss with finasteride and minoxidil since 2015, with intermittent use of minoxidil.

A 28-year-old started finasteride 1mg/day for hair loss, later reducing to 3 times a week. Positive effects include better gym performance, reduced social anxiety, and improved skin health, while negative effects include some erectile dysfunction and nipple sensitivity.

Hair loss sufferers becoming hyper aware of shedding, and the various treatments available for reducing shedding. The conversation also discussed differentiating between shedding and balding, as well as the potential side effects from using certain treatments.

A person in their early 30s is experiencing increased hair shedding after stopping birth control and reducing spironolactone, which they've been on for years. They are concerned about the hair loss, which is different from their usual hereditary pattern, and are seeking advice.

A user applied a homemade topical finasteride solution daily for 35 days, reducing hair shedding significantly with minimal side effects. They plan to continue for 90 days and will provide further updates.

The conversation discusses using tretinoin cream with minoxidil for hair loss treatment. Users suggest applying them separately to avoid reducing effectiveness.

IGFBP‐rP1 shows potential for treating androgenic alopecia by influencing hair cycle transitions. Increasing IGF-1 levels may have similar effects to Minoxidil and 5-AR inhibitors in reducing hair loss.

After using finasteride for 7 months and dutasteride for 5 months, the user experienced a significant reduction in hair shedding and scalp itchiness. They advise patience with hair loss treatments and suggest focusing on a good haircut and reducing stress.

The user experienced worsening hair loss despite using finasteride, minoxidil, and microneedling. Suggestions included reducing microneedling frequency, switching to oral minoxidil, adding tretinoin, and considering dutasteride.

Dutasteride is less commonly prescribed for hair loss because it is not FDA-approved for this purpose, unlike finasteride, which is more accessible and preferred due to fewer side effects. Dutasteride may be more effective in reducing DHT but has a longer half-life and potentially more significant side effects.

OP is experiencing severe side effects from daily Minoxidil, Dutasteride, and Biotin use and is considering reducing Minoxidil to once or twice a week. A response advised seeing a doctor due to heart-related issues.

The conversation is about finding a solution for scalp inflammation related to AGA, with the user expressing frustration that Minoxidil and Finasteride do not address inflammation. The user has researched glucocorticoids and topical NSAIDs for reducing inflammation and seeks advice from specialists.

FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

Hair follicles don't truly die but become severely miniaturized. Treatments like finasteride, dutasteride, and minoxidil can help restore hair by providing nutrients and reducing harmful effects on hair roots.

The conversation is about the potential impact of RU58841 on male fertility, specifically regarding sperm concentration, total count, and motility. The user is curious about the likelihood of RU58841 reducing fertility based on its mechanism of action and comparisons to similar substances.

The user has been dealing with an oily scalp, seborrheic dermatitis, and hair loss for 18 months, using finasteride without improvement. Another user suggested dutasteride for reducing scalp oiliness.

Topical dutasteride may be effective for hair loss by staying in the scalp and minimizing bloodstream absorption, potentially improving hair results and reducing side effects. The user seeks advice on its effectiveness.

The conversation discusses the potential for high doses of dutasteride to completely inhibit scalp DHT and speculates whether this could cure baldness when combined with a topical antiandrogen. Specific dosages mentioned are 0.5 mg reducing scalp DHT by 55% and 2.5 mg by about 79%.

The conversation discusses managing estradiol problems during finasteride treatment. Suggestions include stopping finasteride every 3 months for 2-3 weeks or reducing the dosage.

John has experienced slight hair gains and stability over 20 years using Dutasteride, which is more effective than Finasteride in reducing scalp DHT and maintaining hair. Dutasteride at 0.5mg daily has a similar side effect profile to Finasteride, but at higher doses, it may increase the risk of sexual side effects.