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      community What happened to Pyrilutamide?

      in Technology  1 upvotes 1 year ago
      Pyrilutamide's 0.5% solution showed minimal improvement, while the 1% solution appears more promising but costly. The user is currently using finasteride and oral minoxidil and considering adding Pyrilutamide if effective and affordable.

      community Peak efficacy ($18 for a 4 month supply)

      in Minoxidil  14 upvotes 1 year ago
      The conversation discusses a hair loss treatment regimen involving a homemade topical solution of Minoxidil and Tretinoin, combined with Finasteride and microneedling. Users share advice on Tretinoin application, emphasizing gradual use to avoid skin irritation.

      community AH-001 another topical AR degrader beside GT20029, completed Phase I

       8 upvotes 10 months ago
      AH-001 is a new topical treatment designed to degrade androgen receptors, targeting the root cause of androgenetic alopecia without the side effects of oral treatments like finasteride. It has shown a strong safety profile and good local tolerability in early trials.

      community Fin effects on prostate sensation for MSM

       5 upvotes 4 years ago
      Finasteride may affect prostate sensation and size, with some users reporting easier urination. Concerns exist about prostate shrinkage even at lower doses.

      community Is microneedling worth it when you're on dut and oral min?

      in Microneedling  11 upvotes 6 months ago
      Microneedling may not significantly enhance hair growth when combined with dutasteride and oral minoxidil, as its primary benefit is improving topical absorption. Some users suggest using a 1.5mm depth for potential follicle stimulation, but results and effectiveness vary.

      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

       133 upvotes 2 years ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community Has anyone tried 2% Pyrilutamide from Anagenica?

      in Treatment  1 upvotes 1 year ago
      The conversation discusses using 2% Pyrilutamide from Anagenica for hair loss, as the user did not see results with 1% Pyrilutamide. The user is considering increasing the dosage but is concerned about the cost.

      community DIY copper peptide for microneedling?

       3 upvotes 9 months ago
      The conversation is about using DIY copper peptide (GHK CU) serum for microneedling to address hair loss, with additional treatments including Nizoral for DHT reduction and red light therapy. The user is considering adding Minoxidil but is concerned due to having cats.

      community My transplant review - for anyone who wants to know how it works

       8 upvotes 1 month ago
      A user shared their experience with a hair transplant at Estenova in Istanbul, highlighting the painful injection process but overall satisfaction with the results. They also discussed the importance of using topical treatments and the potential for natural hair loss due to DHT, while other users shared their experiences with PRP and ongoing maintenance with finasteride and minoxidil.

      community Topical Dutasteride Experiment

       1 upvotes 2 months ago
      The user is experimenting with a homemade topical dutasteride formulation to reduce hair loss while minimizing systemic absorption, using MCT oil, almond oil, vitamin E, tea tree oil, and lavender oil. They are monitoring hair growth and side effects, particularly focusing on sexual health, and are open to feedback on their approach.

      community The best Ethanol/Propylene Glycol ratio for home made topical finasteride?

       4 upvotes 2 years ago
      The conversation discusses the best ethanol and propylene glycol ratio for homemade topical finasteride, with a focus on absorption and drying issues. The user shares their experience using a 50% propylene glycol, 30% ethanol, and 20% water solution, and considers adjusting the ethanol content for better results.

      community Dutasteride mesotherapy doesn’t impact your bodies serum hormone levels?

       2 upvotes 1 year ago
      Dutasteride mesotherapy may stabilize hair loss and improve hair without significantly affecting serum DHT levels, but it can still have systemic effects. Users discuss using topical and oral dutasteride, with some experiencing side effects and considering hair transplants.

      community Anyone tried/trying alfatradiol

       5 upvotes 3 months ago
      The conversation discusses using alfatradiol, a weaker estrogen, as a treatment for hair loss, with some users sharing their experiences and challenges in obtaining it. One user mentions using a topical solution containing alfatradiol, cetricin, caffeine, and melatonin, noting no significant hair growth but stabilization.

      community Need supplemental products in addition to oral minoxidil and oral dutasteride

       1 upvotes 1 year ago
      The user has been using oral minoxidil and dutasteride for hair loss without success and is considering adding topical 17α-estradiol, Pyrilutamide, Clascoterone, or cetirizine. They have confirmed low serum DHT levels and are exploring additional treatments due to genetic sensitivity to DHT and prostaglandin D2.

      community 10 months Fin 1mg & micro needling

      in Progress Pictures  260 upvotes 2 years ago
      A user shared their 10-month progress using 1mg finasteride daily and micro-needling, noting significant hair regrowth and no side effects. They plan to add oral minoxidil to boost hair density.

      community Dutesteride time at which maximum serum DHT is supressed?

       5 upvotes 3 years ago
      Maximum serum DHT suppression for finasteride occurs at 8 hours, while for dutasteride, it occurs within 1 to 2 weeks with daily dosing. Dutasteride mesotherapy will be followed by blood tests to check serum DHT changes.

      community Has anyone had a hair transplant while on pyrilutamide?

      in Treatment  4 upvotes 1 year ago
      The user is considering starting pyrilutamide before a scheduled hair transplant, having previously used oral minoxidil and finasteride with worsening results. They also tried dutasteride, which worsened their hair and made their skin oily.

      community Discussion for long term fin or dut/min

       4 upvotes 1 year ago
      Baby hairs can mature with long-term DHT reduction, and Minoxidil can aid this process. Dutasteride mesotherapy is effective and preferable to oral pills, as it directly targets tissues.

      community Dermal incision with verteporfin

       4 upvotes 9 months ago
      Dermal incision with verteporfin is being explored as a potential hair loss treatment by dermatologist Melissa Toyos, with promising before-and-after photos shared on social media. The conversation discusses its potential effectiveness compared to other treatments like Minoxidil, Finasteride, and RU58841.

      community Has anyone used verteporfin + microneedling?

       10 upvotes 2 years ago
      A user is considering using verteporfin with microneedling, oral/topical minoxidil, and RU58841 to treat hair loss. They seek advice on dosage and application methods.

      community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.

       3 upvotes 1 year ago
      DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.

      community Low Dose Naltrexone For Inflammatory Hair Loss

       10 upvotes 1 year ago
      Low Dose Naltrexone (LDN) may reduce inflammation in alopecia conditions. It is discussed as a potential adjunct treatment with finasteride or dutasteride for androgenic alopecia.