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      community PP405 Might Be the Closest We Have to a Upcoming Cure

      in Technology  237 upvotes 1 year ago
      PP405 is considered a promising potential cure for hair loss, with phase 2 trial results expected in February 2025. Hair cloning is also discussed as a potential ultimate solution, despite significant scientific challenges.

      community Female 37/F - On Meds, but no progress. Add PRP?

       4 upvotes 3 years ago
      A 37-year-old woman with androgenetic alopecia is using spironolactone, oral and topical minoxidil, and considering PRP therapy due to lack of progress. She is unable to obtain finasteride, dutasteride, or bicalutamide and is exploring other options like Clascoterone and RU58841.

      community Has anybody tried RU58841 and pyrilutamide together?

      in Chat  10 upvotes 1 year ago
      RU58841 and pyrilutamide are being discussed as potential hair loss treatments, with some users reporting side effects. There is interest in these treatments as alternatives to 5ar inhibitors and oral minoxidil due to concerns about safety and side effects.

      community Q1/Q2 Exciting times ahead - hope!

      in Research/Science  16 upvotes 1 year ago
      The conversation discusses various hair loss treatments, including Breezula, KX826, and PP405, with mixed opinions on their effectiveness compared to finasteride and minoxidil. Some users express skepticism about the new treatments, while others remain hopeful about future developments.

      community Do Platelet-rich plasma, PRP work?

      in Research/Science  13 upvotes 3 years ago
      Someone's brother tried Platelet-rich plasma (PRP) for hair loss; it had minimal effect on hair but improved skin appearance. Microneedling at home was suggested as a more sustainable alternative.

      community PP405 2a study was a safety study. Some rational explaining.

       22 upvotes 1 year ago
      The conversation discusses the safety study of PP405, emphasizing that early trials focus on safety rather than efficacy, and that any efficacy data from such a short study should be viewed skeptically. It also highlights that the information released is primarily for securing funding, and that meaningful efficacy results are expected in later phases.

      community Gray market sources to get gt20029 or pp405?

      in Product  2 upvotes 1 year ago
      The conversation is about sourcing gray market compounds, gt20029 and pp405, for hair loss treatment. The user is interested in these compounds despite their unproven status and potential risks.

      community Is RU58841 safe or is pyrilutamide better option

       7 upvotes 1 month ago
      RU58841 and pyrilutamide are discussed as alternatives to 5AR blockers for hair loss, with mixed opinions on their safety and effectiveness. Some users report positive experiences with RU58841, while others express concerns about its safety.

      community RU58841 Users: How chemically unstable is RU58841 in practice?

      in Technology  2 upvotes 1 year ago
      The conversation discusses using RU58841 mixed with topical minoxidil for hair loss, noting its chemical instability and storage challenges. A user shares their experience using RU58841 with ethanol and propylene glycol, mentioning no significant results yet.

      community Best Sources for High Purity Ru58841

      in Product  2 upvotes 10 months ago
      The conversation is about finding high-purity RU58841 solutions for hair loss treatment, with mentions of Anagenic, Selleckchem, MV Supplement, and rudirect.co.uk as potential sources. Users discuss their experiences and preferences regarding product quality and shipping.

      community The use of peptides to enhance hair growth from wounding

       4 upvotes 9 years ago
      The conversation discusses using peptides BPC-157 and TB-500, combined with microneedling, to potentially enhance hair regrowth. The user plans to try BPC-157 due to its lower cost and reports of hair growth, despite limited human trials and concerns about side effects from other treatments like minoxidil and finasteride.

      community any Ru58841 user ? + What do I need to expect?

      in Product  10 upvotes 1 year ago
      The user is considering adding RU58841 to their current hair loss treatment of finasteride and minoxidil, but is concerned about potential side effects like hairline recession and shedding. Some users report positive results with RU58841, while others experience side effects such as chest pain and dizziness.

      community PP405 Has a Wikipedia Page - WooHoo

       20 upvotes 9 months ago
      PP405 now has a Wikipedia page, generating more discussion and attention. One user plans to continue using finasteride until PP405 is proven effective and widely available.

      community How long do you keep ru-58841 on?

      in Product  1 upvotes 11 months ago
      The conversation discusses the application of RU58841 for hair loss, with the user applying 1.75 mg at 5% concentration for half an hour daily. The user mentions managing seborrheic dermatitis while using this treatment.

      community Fighting Seb Derm + MPB - Winning

       72 upvotes 1 year ago
      The user successfully managed hair regrowth by using a combination of finasteride, dutasteride, minoxidil, and specific shampoos to treat seborrheic dermatitis. They emphasize the importance of maintaining a healthy scalp and are considering food intolerance tests to further address inflammation.

      community Ru58841 20mg….making my own solution

      in Treatment  1 upvotes 1 year ago
      The conversation is about making a 20mg/ml RU58841 solution for hair loss treatment using ethanol and propylene glycol. The user receives advice on calculating the correct amount of RU58841 powder needed.

      community RU58841 longterm use and expectations.

       5 upvotes 4 months ago
      RU58841 has been used by a person for 5 years, effectively regrowing and maintaining hair without noticeable side effects, though there are concerns about potential long-term risks. The user initially tried finasteride but did not achieve the desired results.

      community A New Hair Loss Drug Could Cure Balding and Reverse Graying

       367 upvotes 10 months ago
      ABS-201, a prolactin receptor blocker, shows promise in reversing hair loss and graying, with early success in macaques. Current treatments like finasteride, minoxidil, and RU58841 are still widely used, but new options like PP405 are eagerly anticipated.

      community Need help with RU58841 (preparation + dosage).

      in Treatment  3 upvotes 1 year ago
      The conversation is about using RU58841 for hair loss treatment, specifically mixing it with minoxidil without propylene glycol due to an allergy. The user is considering starting with a lower concentration of RU58841 and making smaller batches to maintain efficacy.

      community Does RU work? I see people buying it and reporting success, but if so why was it discontinued?

      in Treatment  3 upvotes 1 year ago
      RU58841 is a controversial hair loss treatment with mixed reviews; some users report success, often in combination with other treatments like finasteride or minoxidil, while others experience side effects like chest pain. The treatment's discontinuation is speculated to be due to patent expiration and lack of profitability, despite some users continuing to use it as part of a broader regimen.

      community PRP and exosomes combined and places to do in the UK

       1 upvotes 2 years ago
      A user was recommended PRP and exosomes for hair loss and asked about combining them and places to get the treatment in the UK. Other users suggested starting with finasteride and minoxidil due to the high cost and variable success of PRP and exosomes.

      community Are we still getting the PP405 phase 2a results by the end of March?

       32 upvotes 6 months ago
      People are discussing the anticipated release of PP405 phase 2a results, expected by the end of March, with some skepticism about its effectiveness. There is cautious optimism due to past experiences with similar treatments like Breezula, despite concerns about the lack of presentation at the AAD 2026 conference.

      community Petition Alert: Let's Get PP405 Phase 3 Trials in Germany by 2026!

       55 upvotes 1 year ago
      A user is advocating for Phase 3 trials of the hair loss treatment PP405 to be conducted in Germany, citing benefits like a diverse patient base and faster access for European patients. Despite skepticism about the petition's influence, the user believes it can demonstrate significant interest and potentially influence strategic decisions.

      community Some good news for the future.

       98 upvotes 1 year ago
      PP-405, a potential hair loss treatment, shows promise in stimulating dormant hair follicles and may help with various hair loss types. Current treatments like Minoxidil are still recommended as PP-405 is in early trials and may take years to become available.