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GlossaryReceptor Activator of Nuclear Factor Kappa-Β Ligand (RANKL)

protein that promotes bone resorption by activating osteoclasts

Receptor Activator of Nuclear Factor Kappa-Β Ligand (RANKL) is a protein that plays a crucial role in bone metabolism by promoting the formation, function, and survival of osteoclasts, the cells responsible for bone resorption. It is also involved in immune system regulation and has been linked to conditions such as osteoporosis and rheumatoid arthritis.

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community Personal Ranking of Natural/Non-Keto Shampoos For Hairloss

in Ketoconazole 18 upvotes 5 years ago

The conversation ranks natural shampoos used for hair loss, with Pura D'or being the top choice due to its multiple DHT blocking ingredients and value. Other shampoos mentioned include Hims DHT Blocker Shampoo, Bevisen Organic Anti-DHT Shampoo, Ultrax Labs Hair Growth Stimulating Shampoo, and Hairgenics Pronexa Therapy Shampoo, with varying effectiveness and prices.

community Hair Loss Drugs Ranked in Order of Efficacy

in Research/Science 67 upvotes 11 months ago

Dutasteride is likely the most effective treatment for male pattern baldness, followed by finasteride and minoxidil in various forms and dosages. Users discuss personal experiences, dosages, and potential side effects, with some considering combining treatments for better results.

community Best hair loss treatments ranked: a complete guide

361 upvotes 5 years ago

Hair loss treatments, including Dutasteride 0.5mg daily, finasteride 1mg daily, minoxidil 5% 2x daily, dermarolling, low-level light therapy (LLLT), ketokonazole shampoo, and diet optimization; discussing their effectiveness and side effects.

community Selection of Minoxidil with Finasteride Topical Solution Products

in Finasteride/Dutasteride 12 upvotes 4 years ago

The conversation lists various topical hair loss treatments combining Minoxidil and Finasteride, ranking them by price and providing details like concentration and availability. The user also mentions personal positive results with a topical Finasteride-only solution.

community Hair loss treatment tier list by Dr Oscar Muñoz

in Treatment 916 upvotes 3 months ago

Dr. Oscar Muñoz's hair loss treatment tier list suggests oral minoxidil and finasteride are highly effective, while topical treatments like RU58841 and microneedling are less effective. Users discuss the effectiveness of various treatments, with some favoring oral options for their practicality and higher response rates.

community Will we ever hear about HMI -115

in Update 20 upvotes 1 year ago

Hair loss discussion includes treatments Minoxidil, Finasteride, and RU58841. Update on HMI-115 clinical trial expected in July or August.

community piroctone olamine was was very superior than ketoconzole in increasing hairgrowth and reducing itching and danruff?

in Research/Science 15 upvotes 2 years ago

Piroctone olamine is more effective than ketoconazole for increasing hair growth and reducing itching and dandruff. Treatments discussed include Minoxidil, finasteride, and RU58841.

community So is hmi-115 a flop? There are no news about effectiveness. What do you guys think?

in Product 6 upvotes 1 year ago

Hair loss discussion includes treatments Minoxidil, Finasteride, and RU58841. Users question effectiveness of HMI-115 and consider waiting longer for results.

community Physician here AMA – 30M oral Fin 1-1.25 mg daily

in Update 47 upvotes 2 years ago

Hair loss treatments, specifically the use of finasteride, microneedling and potentially oral minoxidil. People discussed their experiences with finasteride, its effects on sexual behaviors, as well as potential solutions such as tadalafil or using other growth factor signal peptides for hope in curing male pattern baldness.

community Evidenced Based Meta-Analyses and Systemic Reviews of Androgenic Alopecia and Treatments

in Research/Science 15 upvotes 4 years ago

Evidence-based treatments for androgenic alopecia, such as minoxidil, finasteride, low-level laser light therapy, dutasteride, platelet-rich plasma, and topical ketoconazole. It discusses the efficacy, safety, and mechanism of action of these treatments, as well as future developments in understanding this polygenic condition.

community Kintor's email response to me, regarding false advertising, and my proposal for them to develop a topical dut formulation with meaningful efficacy.

in Treatment 46 upvotes 3 months ago

Kintor apologized for using misleading images in their advertisements and promised stricter review processes. They are also considering developing a topical dutasteride formulation.

community M23 on Hims Fin and Min solution for 4 months now progress

in Progress Pictures 149 upvotes 1 year ago

The conclusion of the conversation is that some users have seen positive results with the use of finasteride and minoxidil for hair loss, while others have not. It is mentioned that consistent use of these treatments is necessary to maintain results.

community Am I balding? NW -2, on min and fin for 2 weeks now

in Satire 974 upvotes 1 year ago

User discusses hair loss and treatments like Minoxidil and Finasteride. Conversation includes jokes and comments about hairlines and hair growth.

community Be careful when switching from Finasteride to Dutasteride because for more efficacy.

in Finasteride/Dutasteride 13 upvotes 1 month ago

Switching from finasteride to dutasteride may be more effective for hair regrowth due to dutasteride's stronger enzyme inhibition, but combining both drugs could enhance results. Some users report better outcomes with dutasteride, while others recommend a gradual transition to prevent potential hair loss.

community Scientists have found that a naturally occurring sugar in humans and animals could be used as a topical treatment for male pattern baldness | In the study, mice received 2dDR-SA gel for 21 days, resulting in greater number of blood vessels and an increase in hair follicle length and denseness

in Research/Science 634 upvotes 4 months ago

Scientists discovered a sugar gel, 2dDR-SA, that increased hair growth in mice. Users discussed its potential, comparing it to other treatments like Minoxidil and finasteride.

community Fellas, is Arteta world class hair density?

in Satire 361 upvotes 9 months ago

The conversation is about the impressive hair density and hairline of a person, with users attributing it to good genetics and joking about the lack of hair loss despite stress. Specific hair loss treatments like Minoxidil, Finasteride, or RU58841 are not discussed.

community Can RU58841 stop hairloss for a long time?

in Research/Science 11 upvotes 11 months ago

A user is considering using RU58841 to treat hair loss and asks if it can be effective for 4-5 years. Some suggest starting with a lower concentration and debate the safety of RU58841 compared to approved drugs like finasteride.

community Switched from finasteride to dutasteride - 2 month update

in Finasteride/Dutasteride 6 upvotes 1 year ago

The user switched from finasteride to dutasteride for hair loss treatment, but experienced increased libido, itchy scalp, and accelerated hair loss. Another user suggested that genetic variations might cause dutasteride to be less effective and recommended checking for specific genetic markers.

community 5 months post op in 5 days 4500 graphs - hair is starting to fill out nicely 🥹 low dosage RU .25ml on native hairs daily ( avoiding transplant hair ) prp once a month. No other medications and ALL hair loss has halted - Next update will post up between 6-8 months.

in Progress Pictures 520 upvotes 1 year ago

The user "Curious_Conflict_959" shared a progress picture of their hair transplant after 5 months. They used a low dosage of RU on native hairs and had PRP treatments. All hair loss has stopped.

community Follicum releases some data from previous phase 2a trial

in Research/Science 13 upvotes 1 year ago

Follicum discovered that their drug FOL-005 increased hair count by 12 hairs per cm2 in patients with less than 255 hairs per cm2 and is planning a phase 2b trial. They are currently fundraising for the trial, and the drug may also be effective for women.

community Finasteride, Minoxidil, Ketoconazole 1 year update

19 upvotes 9 years ago

The user used finasteride, minoxidil, and ketoconazole for hair loss prevention. After one year, there was no noticeable hair regrowth, but no further hair loss occurred.

community Theory And Observation: Why Being Bald Can Really Work

in Shaved/buzzed 88 upvotes 8 months ago

The original poster believes shaving his head made him more attractive to a specific group of women, despite being less attractive overall. The conversation includes various opinions on attractiveness, with some agreeing that being bald can work for certain men, while others suggest maintaining hair is generally more appealing.

community For those who switched from finasteride to Dutasteride !

in Chat 43 upvotes 9 months ago

People discussed switching from finasteride to dutasteride for hair loss treatment. They reported satisfaction with dutasteride, noting it was more effective than finasteride, particularly after finasteride's effects diminished, and some experienced additional benefits like cost savings and stabilized hair loss, rating dutasteride highly as a treatment.

community Seeking Feedback on My Hair Transplant Results: Is My Hairline Proper?

in Progress Pictures 461 upvotes 9 months ago

The conversation is about a user sharing their hair transplant results and seeking feedback. They are taking finasteride, minoxidil, oral minoxidil, vitamins, and using special shampoo to maintain their hair.

community NW5 at 19. How many grafts do I need?

in Transplants 140 upvotes 1 year ago

A 19-year-old with rapid hair loss since 16 is considering a hair transplant but refuses to take finasteride or any 5α-Reductase inhibitors. They are currently using minoxidil, tretinoin, and microneedling with a Derminator 2, and only want hair until age 27.

community Why is Kevin Mann (Haircafe) Hated?

in Chat 62 upvotes 1 year ago

Hair loss treatments, including microneedling, minoxidil, finasteride and RU58841; the efficacy of these treatments; criticisms of Kevin Mann's content related to his selective data presentation and biases towards certain treatments; and other topics such as DHT being labeled a "trash hormone" and critiques of other hairloss YouTubers.

community Hold up... CosmeRNA/SAMiRNA is actually coming real soon?

in Technology 31 upvotes 1 year ago

A user discovered CosmeRNA, a new hair loss treatment with clinical research backing, set to release soon. The conversation revolves around its potential effectiveness, cost, and how it compares to existing treatments like Minoxidil and Finasteride, with some users expressing hope for a side-effect-free option.

community Should I dedicate my university studies to solving hair loss?

in Research/Science 373 upvotes 1 year ago

A 20 year old male who is balding and considering switching to a biology/chemistry program in order to find a low-cost, accessible solution for hair loss. Replies discuss the merits of this idea as well as potential treatments such as Minoxidil, finasteride, RU58841, TM5614, and ADQ.

community Anyone else find it funny all of us on here stress about hair loss daily and take pills for it and take time everyday to apply minoxidil or RU meanwhile we all have friends who don’t even think about hairloss rocking their perfect NW0 hairlines and thick hair?

in Chat 255 upvotes 3 years ago

People on a forum are discussing the irony of stressing over hair loss and using treatments like Minoxidil and Finasteride, while others have naturally perfect hair without any effort. They share personal experiences and acknowledge that everyone has insecurities, with some accepting their situation and others finding it frustrating.

community Hair Remedies that Don't Work for Anybody Seeking Hair Regrowth

in Treatment 7 upvotes 4 years ago

Hair loss treatments discussed include minoxidil, finasteride, and RU58841. Salon products and supplements generally don't work for hair regrowth unless there's a severe nutritional deficiency, while hormonal treatments like estrogen and spironolactone can be effective.