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Glossary Psoralen and Ultraviolet A Therapy

combines a drug and UVA light to treat skin conditions

Psoralen and Ultraviolet A Therapy (PUVA) is a type of photochemotherapy used to treat various skin conditions, including psoriasis, vitiligo, and certain types of eczema. The treatment involves taking a drug called psoralen, which makes the skin more sensitive to ultraviolet A (UVA) light, followed by exposure to UVA light. This combination helps to slow down the excessive growth of skin cells and can reduce symptoms like itching and inflammation.

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community DUPA - Impossible to cure, so giving up

in Update 3 upvotes 11 months ago

The user diagnosed with DUPA tried treatments like dutasteride, finasteride, RU58841, and minoxidil without success and is considering a hair system. They hope for a future cure, possibly with PP405, and others suggest options like scalp biopsy and SMP.

community Hair repigmentation of poliosis circumscripta in androgenetic alopecia patient treated with exosomes and fractional picosecond laser

2 upvotes 2 years ago

Exosomes combined with fractional picosecond laser treatment were effective in treating androgenetic alopecia and promoting repigmentation in white hair patches. The role of exosomes in hair repigmentation, particularly in conditions like poliosis, is not well-studied.

community Verteporfin Update #1: Overview of Verteporfin Procedure Day | Feller & Bloxham Medical

6 upvotes 3 years ago

The conversation discusses the use of Verteporfin in treating hair loss. Specific treatments mentioned include Minoxidil, Finasteride, and RU58841.

community What happened with verteporfin?

30 upvotes 1 month ago

Verteporfin, combined with microneedling, shows promise for hair regrowth by allowing hair follicles to grow in wounds, but it's expensive and painful. Pai-1 inhibitors may also help prevent hair loss by degrading fibrosis, and some users continue using minoxidil alongside these treatments.

community Question about topical part of treatment

2 upvotes 2 years ago

The user is using a combination of oral Dutasteride and Minoxidil, and a topical formula with Finasteride, Minoxidil, and Hydrocortisone, along with rosemary oil, coconut oil, ginseng, and a derma roller. They are also using LLLT therapy and are questioning the timing of the laser cap session in relation to the topical application.

community Shedding from Red Light Therapy ( LLLT )

1 upvotes 2 years ago

A 31-year-old uses Minoxidil, RU58841, Reviv Hair Serum, and Ketoconazole shampoo for hair loss but avoids finasteride. They plan to reintroduce red light therapy (LLLT) and Eucapil despite previous shedding concerns.

community Pyrilutamide with Alfatradiol and minoxidil (23M)

in Treatment 2 upvotes 9 months ago

The user experienced side effects from a hair loss treatment and is considering using pyrilutamide, alfatradiol, and possibly minoxidil. They are unsure about starting minoxidil immediately or waiting to see the effects of the other treatments.

community If pp405 isnt the “cure” is there anything else that’s promising thats atleast better than min or dut?

20 upvotes 5 months ago

Hair cloning and new treatments like ET-02, Veradermics (vdphl01), and wound-induced hair neogenesis show promise but are not yet widely available. Current effective treatments include minoxidil, finasteride, and dutasteride, with early intervention being crucial for better outcomes.

community Tretinoin + minoxidil and red-light?

in Minoxidil 2 upvotes 1 year ago

The user has been using minoxidil for over a year with little success, added tretinoin cream, and is considering adding red light therapy. They are advised to use moisturizer to counteract skin sensitivity from tretinoin.

community Pp405 AAD presentation tomorrow - fingers crossed - what to expect?

in Research/Science 84 upvotes 5 months ago

New hair loss treatments PP405 and VDPHL01 are discussed with skepticism and hope, alongside existing treatments like minoxidil and finasteride. Users express frustration over limited progress since the 1980s but remain cautiously optimistic.

community Verteporfin and KY19382 experiment

80 upvotes 1 week ago

The conversation discusses an experiment involving hair loss treatments, including the use of Verteporfin, KY19382, dutasteride, oral and topical minoxidil, AHK-Cu, and microneedling. The experiment aims to test the effectiveness of these treatments in promoting hair growth and healing without scarring, with updates planned every few months.

community Potential Cure?! Verteporfin- unlimited HT

41 upvotes 2 years ago

The conversation discusses verteporfin as a potential treatment for hair regeneration, which could lead to unlimited hair transplants by healing the donor area. Some users are considering using verteporfin now, while others are hopeful it will be available for future hair transplants.

community can someone help me identify these pls

in Treatment 9 months ago

The user is experiencing diffuse thinning and inflammation despite using 2.5mg dutasteride daily, ciclopirox, and ketoconazole shampoos. They are considering treatments like hydroxychloroquine and JAK inhibitors due to suspected scarring alopecia and have faced challenges in obtaining a scalp biopsy.

community Any other treatments to still be hopeful for?

in Research/Science 20 upvotes 2 years ago

The conversation discusses the potential of new hair loss treatments, with a focus on pyrilutamide, gt20029, and topical alfatradiol, and the possibility of improving their effectiveness through methods like increased concentration and microneedling. Dutasteride is also mentioned as a stronger option.

community Red light therapy that works well

5 upvotes 1 year ago

Red light therapy with dual wavelengths (650nm and 850nm) can stimulate hair regrowth without DHT blockers. Consistent use of a panel with these wavelengths has shown positive results in hair regrowth.

community Targeting multiple AGA mechanisms with commonly available substances

4 upvotes 7 years ago

The conversation discusses using a multimodal approach to treat androgenic alopecia, including substances like gamma-linolenic acid, DHA, sulforaphane, melatonin, cetirizine, astaxanthin, fisetin, apigenin, curcumin, limonene, genistein, and berberine. Users also mention using ketoconazole, minoxidil, and low-level laser therapy (LLLT) as part of their hair loss treatment regimens.

community Reducing Fibrosis in Hair Loss: Topical Pirfenidone

59 upvotes 5 months ago

Topical pirfenidone is highlighted as an effective anti-inflammatory and anti-fibrotic treatment for hair loss, particularly in addressing perifollicular fibrosis, which may enhance the effectiveness of standard treatments like finasteride and minoxidil. The user also uses calcipotriol, MCT oil, ciclopirox shampoo, and benzoyl peroxide shampoo as part of their regimen.

community Whoever had success with PYRILUTAMIDE, please give us hope outside of 5AR inhibitors.

in Product 8 upvotes 2 years ago

Users discuss using pyrilutamide for hair loss, seeking alternatives to 5AR inhibitors. They mention using minoxidil, ketoconazole shampoo, and RU58841.

community Pelage Pharmaceuticals’ PP405 and its Impact on Follicular Regeneration to be Presented at the American Academy of Dermatology (AAD) Annual Meeting 2026

122 upvotes 5 months ago

PP405 shows promise in regenerating hair by activating dormant follicles. Other treatments like VDPHL01 and Breezula are also advancing, providing new hope for hair loss solutions.

community 0.25 alfatradiol or 0.5 Pyrulitamide ?

4 upvotes 11 months ago

The conversation is about choosing an anti-androgen for hair loss treatment, with options being alfatradiol and pyrilutamide. Alfatradiol is considered a better choice due to its established use, while pyrilutamide is more experimental.

community Red Light Therapy: my experience

14 upvotes 2 years ago

A user shared their positive experience with the Omnilux Red Light mask for skin and potential hair benefits, while also using Minoxidil, Dutasteride, and RU58841. They recommend the mask for those interested in skincare and red light therapy, despite being unsure of its effectiveness for hair growth.

community New topical claims complete reversal of AGA in 3 months

18 upvotes 9 years ago

A new topical treatment called RT1640 claims to reverse AGA using cyclosporine A, Minoxidil, and a new chemical entity, RT175. Users are skeptical due to lack of clinical trial data and inconsistent before-and-after photos.

community Dermatology expert panel on permanent chemotherapy induced alopecia (PCIA)

2 upvotes 11 months ago

Chemotherapy can cause permanent hair loss similar to androgenetic alopecia. Oral minoxidil and scalp cooling are suggested treatments.

community Pyrilutamide +Alfatradiol 0.1% , no Hairloss anymore

in Treatment 43 upvotes 1 year ago

OP experienced diffuse thinning for 11 years and used Minoxidil and Finasteride previously. They now use Pyrilutamide 0.5% and Alfatradiol 0.1%, resulting in significantly reduced hair loss.

community Would Verteporfin potentially work for scarring alopecia?

5 upvotes 4 years ago

Verteporfin is discussed as a potential treatment for scarring alopecia. Minoxidil is suggested as an alternative treatment.

community Verteporfin Update with Dr Blake Bloxham

28 upvotes 2 years ago

The conversation discusses Dr. Blake Bloxham's experiment with Verteporfin for hair loss, with one person suggesting more doctors should try it as it seems beneficial. Another comment notes that results at 4-5 months were not very impressive.

community pyrilutamide - did anybody had any success on it?

14 upvotes 4 years ago

Potential success with the hair loss treatment Pyrilutamide, and possible group buying opportunities for it along with other treatments such as Finasteride and Minoxidil.