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GlossaryFluoxetine (Prozac)

medication used to treat depression and anxiety disorders

Fluoxetine, commonly known by the brand name Prozac, is a selective serotonin reuptake inhibitor (SSRI) used primarily to treat depression, anxiety disorders, obsessive-compulsive disorder (OCD), and certain eating disorders. It works by increasing the levels of serotonin in the brain, which helps improve mood and emotional stability.

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community should finasteride be taken with food or without food?

in Treatment 6 upvotes 2 years ago

The conversation is about the best way to take finasteride for hair loss, questioning whether it should be taken with food or on an empty stomach for optimal results. People are sharing their experiences with taking finasteride alongside meals.

community Allopregnanolone deficiency by 5-ari inhibition (fin/dut users)

in Finasteride/Dutasteride 11 upvotes 1 year ago

The conversation is about managing allopregnanolone deficiency caused by 5-alpha-reductase inhibitors like finasteride or dutasteride. Specific treatments discussed for hair loss include Minoxidil, finasteride, and RU58841.

community Help?

7 upvotes 8 years ago

A 21-year-old female is experiencing rapid hair shedding and receding hairline despite trying various treatments like hydration, vitamins, and castor oil. Medical tests showed normal results, and she seeks advice as the hair loss continues.

community Has anyone successfully tapered off finasteride?

7 upvotes 9 years ago

A user is considering tapering off finasteride due to concerns about long-term side effects and cost, and is exploring alternatives like zinc and saw palmetto. Their current regimen includes finasteride, Adderall, zinc, bupropion, fish oil, baby aspirin, Rogaine foam, and ketoconazole shampoo.

community Just got brand name Avodart when I ordered generic

in Finasteride/Dutasteride 122 upvotes 4 months ago

A user received brand name Avodart instead of generic dutasteride for a lower price. Another user mentioned experiencing depression as a side effect but prefers having hair.

community Anyone else not have hobbies anymore because of this?

in Chat 117 upvotes 1 year ago

The user is expressing an obsession with hair loss and spends all their time researching and discussing it. Other users suggest seeking therapy and focusing on other aspects of life.

community I’m just Going to let Nature take its Course

in Chat 213 upvotes 1 year ago

The post and conversation are about a 23-year-old deciding to stop using finasteride for hair loss due to potential erectile dysfunction risks, sparking a debate about the benefits and side effects of hair loss treatments.

community Why I Will be Accepting Baldness

in Chat 204 upvotes 1 year ago

User decides to accept baldness due to mental health issues with finasteride. Others suggest considering hair systems, topical finasteride, or RU58841 as alternatives.

community Shrooms have done more for my hair loss than all of my hair supplements/medications combined.

in Satire 408 upvotes 1 year ago

Finding acceptance of hair loss through psychedelics, and the potential benefits of shrooms. Discussions include sharing experiences with minoxidil, finasteride, nutrafol, laser therapy, micro needling, as well as mental health concerns such as depression, suicidal thoughts, and self-esteem.

community I don’t even care about my hair I just like taking drugs

in Satire 1 year ago

A user's experimentation with various hair loss treatments, including medications and topical applications; as well as their desire to experience unusual sensations through the use of drugs.

community My experience with 1mg fin eod

in Finasteride/Dutasteride 18 upvotes 1 year ago

A 30-year-old man shared his experience with finasteride, taking 1mg every other day, which led to sexual side effects and other issues, prompting him to stop the treatment despite initial hair improvement. He previously tried natural methods and minoxidil without much success and is now considering a buzzcut.

community 6 week update fellas, 5mg oral minoxidil. Pics are 2nd June – 10th July

in Progress Pictures 2 years ago

, you can find it online with a script This user was discussing their progress with hair loss treatments including 5mg oral Minoxidil and combining 3mg oral Minoxidil with MTF HRT. They also discussed side effects of increased body hair in other parts of the body.

community When I’m 60 and finally off the fin after 40 years and look at my semen

in Satire 862 upvotes 2 years ago

Hair loss treatments discussed include Minoxidil, Finasteride, and RU58841. Users share experiences with Finasteride, mentioning watery semen as a side effect and weighing its importance against maintaining hair.

community How to keep taking finasteride after getting gynecomastia as a side effect (Full guide and 4 year search complete).

in Finasteride/Dutasteride 52 upvotes 3 years ago

User experienced gynecomastia from finasteride and found a solution using liposomal topical finasteride. This method minimizes side effects and is effective for hair loss treatment.

community Prolactin’s role in antitumor activity of the immune system – a safety concern for HMI-115?

in Research/Science 3 upvotes 1 year ago

Hair loss discussion includes treatments Minoxidil, Finasteride, and RU58841. Prolactin's role in immune system's antitumor activity raises safety concerns for HMI-115.

community Protac degradation of the androgen receptor in mice shows good efficacy and no systemic drug could be found

in Research/Science 47 upvotes 1 year ago

The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.

community Further prolactin research....

in Research/Science 6 upvotes 10 months ago

HMI 115 did not work as expected for hair regrowth in humans, unlike in macaque monkeys. There is anticipation for further research on prolactin's role in hair loss, with expectations that pharmaceutical companies will likely solve this before universities.

community Does lowering serum prolactin lower prolactin in the scalp?

in Research/Science 13 upvotes 10 months ago

The conversation discusses whether not masturbating (semen retention) affects hair loss, with opinions varying but generally dismissing the idea. Some participants mention using hair loss treatments like Minoxidil, Finasteride, and RU58841, but the effectiveness and relation to prolactin levels in the scalp are debated.

community Lowering scalp prolactine - Any ideas ?

in Treatment 2 upvotes 1 year ago

The conversation is about finding the best method to lower scalp prolactine, with suggestions like P5P and Melatonin. The user also mentions HMI115 as a potential treatment and seeks feedback from those who have tried these methods.

community Whats up with Prolactine these days?

in Research/Science 20 upvotes 1 year ago

The conversation discusses the potential role of prolactin in hair loss and mentions treatments like HMI115, mucuna pruriens, Zinc, and B6 P5P for lowering prolactin levels. It also touches on the use of natural compounds and the lack of studies due to funding issues.

community does lowering your prolactin levels regrow hair?

in Research/Science 10 upvotes 1 year ago

The potential of lowering prolactin levels to regrow hair, with a reference to Bayer's drug HMI 115 which has been indicated as having this effect. Treatments mentioned include Minoxidil and Finasteride, as well as RU58841.

community Kintor Pharmaceutical Announces AR-PROTAC (GT20029) Approved for Acne and Androgenic Alopecia Clinical Trials in China

in Technology 14 upvotes 3 years ago

The conversation discusses the approval of Kintor Pharmaceutical's AR-PROTAC (GT20029) for clinical trials in China for acne and androgenic alopecia. One user expresses optimism about new treatments being developed and seeks clarification on how the new drug works, specifically if it temporarily degrades the AR protein to reduce DHT sensitivity in hair follicles.

community On the topic of HMI-115 and prolactin: has anyone tried adding Vitamin B6 (P-5-P) to their topical solutions?

in Research/Science 7 upvotes 1 year ago

The conversation discusses the potential benefits of adding Vitamin B6 (P-5-P) to topical hair loss treatments like RU58841, finasteride, or minoxidil. The user suggests that Vitamin B6 might enhance these treatments by naturally lowering scalp prolactin.

community Hmi-115 hair loss cure, how does it work? Is there a relationship between prolactin and DHT?

in Research/Science 9 upvotes 1 year ago

Hair loss linked to DHT and prolactin levels. Hmi-115 cure discussed, along with Minoxidil, Finasteride, and RU58841 treatments.

community How can a drug which increases prolactin, cause regrowth of hair?

in Chat 6 upvotes 1 year ago

Minoxidil increases hair count despite high prolactin being linked to hair loss. Blocking DHT is effective, but not always necessary; HMI-115 is a promising treatment for androgenetic alopecia.

community Thoughts on taking hair loss medicine / treatment for proactive measures (age prevention)

in Chat 1 upvotes 5 months ago

A 28-year-old is considering using topical 0.3% finasteride and 6% minoxidil spray to prevent further hairline recession. They are unsure if this treatment is too drastic for their current level of hair loss and seek advice on application methods.

community Is Vitamin B6 + Pyridoxine the same as P5P? Want to use it to reduce my Prolactin.

in Treatment 2 upvotes 11 months ago

The user is considering using P5P to reduce high prolactin levels and is questioning if oral minoxidil could be contributing to the issue. They are also debating whether to switch from oral to topical minoxidil.

community Mucuna pruriens, dopamine and prolactin. Natural route with oils.

in Treatment 2 upvotes 1 year ago

The post discusses using Mucuna pruriens, essential oils, and dermarolling for hair loss treatment. The user also mentions pausing testosterone-boosting herbs due to side effects like acne and hair loss.

community Is anyone taking both boron and p5p to lower SHBG and Prolactin respectively? What are you experience on this?

in Update 6 upvotes 1 year ago

The user is applying topical finasteride with stemoxydine for hair loss and has noticed hair thickening but no regrowth after two months. They also report high SHBG and prolactin levels and a lack of morning erections, even on low doses of medication.

community Kintor Pharma Announces Completion of Subject Enrollment and Dosing in Phase I Clinical Trial of AR-PROTAC(GT20029) in the US_Kintor Pharmaceutical Limited

in Research/Science 61 upvotes 2 years ago

Kintor Pharma finished enrolling and dosing participants in a Phase I trial for a hair loss treatment called AR-PROTAC (GT20029). The effectiveness of another drug, pyrilutamide (KX-826), for hair loss will be clearer after a Phase 2 trial expected to complete in January 2023.