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The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

The post discusses the rarity of baldness among South Korean men. Users suggest this could be due to early treatment, high beauty standards, accessibility of healthcare, and genetics. Treatments like finasteride and dutasteride are commonly used, and hair transplants are also popular.

A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

The user "Top_Replacement_7777" shared their positive results with finasteride for hair loss. They asked about maintaining their hair with finasteride and the impact of vaping on hair growth. Another user reassured them that vaping wouldn't affect their progress.

User Basic_Football999 discusses concerns about negative dutasteride experiences. Replies suggest dutasteride is effective, but some users may have issues with dosing frequency or genetic factors affecting results.

User experienced hair regrowth after 5 months on oral minoxidil and finasteride. Others praised the impressive results and mentioned the importance of combining treatments for best results.

HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

Most hair loss treatments are ineffective; only finasteride, dutasteride, and minoxidil show effectiveness.

The conversation discusses the side effects of finasteride, including low libido and erectile dysfunction, and the possibility of these effects being permanent, known as post-finasteride syndrome (PFS). Some users report personal experiences with PFS and debate whether the condition is real, with varying opinions on the reversibility of side effects and the role of individual biology.

A user's father, mostly bald for 20 years, is regrowing hair using a serum called "Skrzypovita Serum Pro" without minoxidil. The user is curious about which ingredients might be causing hair growth.

A user's successful hair regrowth after 7 months of using 5% minoxidil, 1mg finasteride, and adding micro needling 4 months ago. The user also took biotin, fish oil, and collagen supplements, and reduced finasteride intake to once every 3 days due to minor libido decay.

This conversation was about a user named Substantial_Pen_1099 who has been using an regimen of 5mg oral minoxidil, 1mg finasteride everyday, 2% keto shampoo every three days, and weekly 0.5mm dermarolling for hair loss treatment over the course of 3 months. Others in the conversation expressed disbelief at their progress, to which Substantial_Pen_1099 provided video proof as evidence.

The post and conversation are about a user's experience with hair loss treatments, specifically switching from finasteride to dutasteride. The user experienced significant hair shedding after the switch, with others suggesting patience, noting similar experiences, or questioning the user's decision and medical consultation.

The user shared impressive hair growth results after 7 months using a regimen of dutasteride, topical minoxidil, and biotin, alongside a healthy lifestyle. The conversation humorously discusses extreme and unconventional hair loss treatments, with many users expressing amazement and curiosity about the progress.

The conversation discusses the potential market release of a hair loss treatment called GT20029 by Anageninc, with users expressing interest and discussing the importance of safety and effectiveness. Some users plan to contact Anageninc to show demand for the product.

The conclusion of the conversation is that the user, Lead_Tasso, is expressing gratitude for the community's help in restoring their confidence in treating hair loss. They have been using finasteride (fin) and minoxidil (min) and have also been taking hair and nail vitamins.

The conversation discusses why CB-03-01, a potential hair loss treatment, isn't widely discussed despite evidence of its effectiveness and safety. Some users mention other treatments like melatonin, procianidin b2, and RU58841, debating their effectiveness and safety.

This conversation discussed the side effects of Minoxidil for hair loss, with users sharing their experiences. Treatments such as Retinol and Tretinoin were suggested alongside topical or oral Minoxidil to reduce any negative impacts.

Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

TWIST-1 gene's role in hair loss and potential as a treatment target. Inhibiting TWIST-1 may prolong hair growth and reduce hair follicle sensitivity to DHT.

Hair loss theories discussed include poor blood flow, scalp tension, inflammation, and DHT. Treatments mentioned are massaging scalp, minoxidil, finasteride, and RU58841.

Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

A user is experiencing genetic hair loss and is using spironolactone and minoxidil without success. They are considering switching to vegan protein powder due to digestive issues and are concerned if it will worsen hair loss.

The conversation discusses whether whey protein and creatine worsen hair loss. Some users report hair loss with creatine use, while others do not; opinions on whey protein's effects are mixed. Treatments mentioned include PRP, minoxidil, and finasteride.

Eating soy protein daily might slow down baldness due to its estrogen-stimulating effects. The user cannot use finasteride because it causes insomnia.

The user experienced an elevated heart rate from using topical Minoxidil and discontinued its use. They found that adding a daily protein shake helped with telogen effluvium.

SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

A group buy for testing a compound targeting Twist1 protein as a potential hair loss treatment. Inhibiting Twist1, which keeps hair follicles in growth phase, may prevent hair loss with minimal side effects.