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GlossaryProstaglandins

group of lipid compounds with hormone-like effects in the body

Prostaglandins are a group of lipid compounds that are derived from fatty acids and have hormone-like effects in the body. They play a crucial role in various physiological processes, including inflammation, blood flow, the formation of blood clots, and the induction of labor. Prostaglandins are also involved in the regulation of hair growth and can influence conditions like alopecia.

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community Has anyone here tried topical synthetic prostaglandins (Bimatoprost, Latanoprost, cetirizine) to stimulate hair growth?

in Treatment 7 upvotes 3 months ago

The conversation discusses using topical synthetic prostaglandins like Bimatoprost, Latanoprost, and cetirizine for hair growth. The user shares a link suggesting these treatments may be effective.

community Oral Castor Oil and your experience

in Treatment 9 upvotes 2 years ago

A user experienced significant hair shedding and thinning after using oral castor oil for hair loss. Other users suggested seeing a dermatologist and noted that castor oil is typically used for constipation.

community UPDATE: The theory that explains everything. Please help me make this big!

in Research/Science 449 upvotes 3 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

community For those of you who are getting facial skin side effects (aging, dark circles) from minoxidil, try this, it helped me.

in Minoxidil 11 upvotes 3 years ago

The conversation provides tips to reduce facial skin side effects from Minoxidil, such as changing pillowcases, sleeping on the back, careful application, hydration, and taking breaks. One reply suggests that alcohol in Minoxidil formulations, not Minoxidil itself, may cause skin aging.

community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

in Research/Science 92 upvotes 2 years ago

The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.

community Autoimmune issue?

in Question 2 upvotes 6 years ago

The user experienced severe hair loss, itchy scalp, and skin issues after trying no-shampoo, and wonders if it's male pattern baldness or an immune issue. They have a history of eczema, dermatitis, and jock itch, and have tried various treatments like coconut oil, peppermint, pumpkin seed, and onion.

community Minoxidil Alternative? | Bimatoprost & Latanoprost

in Minoxidil 13 upvotes 1 year ago

Exploring alternatives to Minoxidil for hair loss, such as Bimatoprost and Latanoprost, as well as potential treatments like Finasteride and RU58841.

community Castor Oil - Yay or Nay?

in Product 10 upvotes 3 years ago

The conversation discusses the potential benefits of castor oil for hair thickening, with one user noting it may increase prostaglandin E2 and decrease PGD2. The original poster plans to take 1-2ml orally daily.

community Fagron TrichoTest says Finasteride won't help

in Treatment 13 upvotes 4 months ago

The user received a Fagron TrichoTest indicating that Finasteride, Dutasteride, and Minoxidil are not effective for them, recommending Latanoprost, Spironolactone, IGrantine-F1 TM, and Trichoxidil instead. Other users expressed skepticism about the test's validity and suggested sticking with proven treatments like Finasteride and Dutasteride.

community Latanoprost from the gray market?

in Chat 4 upvotes 5 months ago

The conversation discusses sourcing pure latanoprost from the gray market for research and making a homemade solution. Concerns about potential dangers and experiences with this method are raised.

community Interesting / Relevant Information

in Research/Science 1 upvotes 11 months ago

The conversation provides scientific sources on hair loss treatments like finasteride, minoxidil, and others, aiming to help individuals make informed decisions about their treatment options. It also discusses phytochemicals as alternative treatments due to concerns about side effects from drug-based therapies.

community Peptides that Stop Hair Loss? | In-depth Literature Review Video

in Research/Science 71 upvotes 4 months ago

Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.

community Hair loss causes are still a myth.

in Chat 16 upvotes 3 years ago

The conversation discusses the complexity of hair loss causes, suggesting that DHT sensitivity alone doesn't fully explain it. Treatments mentioned include finasteride and dutasteride.

community Best hair loss treatments ranked: a complete guide

361 upvotes 5 years ago

Hair loss treatments, including Dutasteride 0.5mg daily, finasteride 1mg daily, minoxidil 5% 2x daily, dermarolling, low-level light therapy (LLLT), ketokonazole shampoo, and diet optimization; discussing their effectiveness and side effects.

community 8 months on Fin and Min, with no change. Give up or switch to dut and add micro needling?

in Progress Pictures 18 upvotes 5 months ago

A user has seen no progress after 8 months on finasteride and minoxidil and is considering switching to dutasteride and adding microneedling or quitting and getting a hair system. Another user suggests adding microneedling and dutasteride and buzzing the hair down.

community A reasonably reputable guy claims that he has reversed his hairloss. Could be an interesting read.

16 upvotes 9 years ago

A user shared a blog post by "swissTemples" claiming to have reversed hair loss using a combination of treatments including suppressing PGD2 and increasing PGE2. The user noted that "swissTemples" has been banned from forums, possibly due to conflicts of interest.

community Dental technician is convinced that he has found the cause of pattern hair loss

in Research/Science 314 upvotes 3 months ago

A dental technician claims malocclusion causes pattern hair loss due to poor scalp circulation. Users debate this, noting treatments like finasteride, minoxidil, and microneedling focus on DHT and blood flow.

community Fevipiprant 2019!

17 upvotes 8 years ago

The conversation discusses Fevipiprant, an asthma drug that may block CRTH2 and potentially stop male pattern baldness (MPB) without inhibiting DHT. It also mentions the use of finasteride and dutasteride for hair loss.

community Medications that cause extra hair growth

in Research/Science 123 upvotes 1 year ago

The post discusses the side effects of various drugs causing excess hair growth, questioning why only minoxidil is used in the hair loss industry. The conversation includes users sharing their experiences and concerns about potential side effects of these drugs, with some preferring baldness over potential health risks.

community What all oils could be useful to augment hair growth

in Finasteride/Dutasteride 4 upvotes 5 months ago

The user uses 1mg fin every other day, a topical solution of 5% min + 0.1% fin nightly, and seeks advice on oils for hair growth. Replies suggest oils are ineffective and recommend sticking with fin and min treatments.

community Anyone using Peppermint oil/ similar oils and seeing growth?

in Research/Science 6 upvotes 5 months ago

Peppermint oil may be beneficial for hair growth, potentially outperforming minoxidil. Users discuss its effectiveness compared to other treatments like finasteride and RU58841.

community What's your opinion on oils? Should I add those to my topical fino/mino?

in Product 6 upvotes 7 months ago

The user is considering adding castor, rosemary, and pumpkin oils to their current hair loss treatment of finasteride and minoxidil. They are unsure about the effectiveness of these oils.

community People who apply peppermint oil, rosemary… how frequent?

in Chat 8 upvotes 1 year ago

The conversation is about the frequency of applying peppermint oil and rosemary for hair loss and what carrier oil is best to use. People are sharing their results from using these treatments.

community My Theory Regarding a Cause and Cure for Androgenetic Alopecia

in Treatment 98 upvotes 4 years ago

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

community Daily aspirin is ruining your Min. gains

in Minoxidil 5 upvotes 1 year ago

Aspirin reduces the effectiveness of minoxidil for hair loss. Quercetin and 5-ASA medications also inhibit the necessary enzyme for minoxidil to work.

community Zyrtec (Cetirizine) antihistamine for hair growth compared to Minoxidil NIH study

in Minoxidil 35 upvotes 1 year ago

The conversation discusses the potential of topical cetirizine (Zyrtec) for hair growth in comparison to minoxidil, noting cetirizine's ability to reduce prostaglandin D2, which inhibits hair growth. Users share mixed experiences with cetirizine for allergies and scalp health, and there's a mention of the risk of dementia with long-term antihistamine use.

community What else is good. Besides the big 3.

in Chat 36 upvotes 1 month ago

Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

community Pyrilutamide is working but not strong enough, how long should i wait for noticeable results?

in Update 3 upvotes 1 year ago

User discusses Pyrilutamide's effectiveness for hair loss, needing more time for results. Others suggest waiting 6-12 months and ask about side effects.

community Finasteride gyno experience and in dire need of advice

in Finasteride/Dutasteride 7 upvotes 4 years ago

A user experienced puffy nipples and lumps from finasteride, leading to a dilemma between continuing treatment with potential surgery or accepting hair loss. They restarted finasteride at a lower dose with supplements but still face side effects and are seeking advice on whether to persist or stop.

community Reddit’s amatorial meta analysis of 17 already avaliable hair loss prevention treatments that were found to be effective in clinical studies but are not FDA approved for MPB. PROS and CONS. (2022 Guide if Finasteride and Minoxidil are not working/ give you sides/are not enough) 77 studies linked!

in Research/Science 586 upvotes 2 years ago

The post and conversation are about hair loss treatments that have been found to be effective in studies. There are 19 different treatments mentioned, including oral minoxidil, oral dutasteride, topical finasteride, RU58841, and more. The best treatment for an individual depends on factors like availability, cost, side effects, and personal preferences.