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GlossaryPromoter Region (promoter)

specific DNA sequence where RNA polymerase binds to initiate transcription

The promoter region is a specific sequence of DNA located near the start of a gene that acts as a binding site for RNA polymerase and other transcription factors. This region essentially "promotes" the initiation of transcription, the process by which the genetic code from DNA is copied into messenger RNA (mRNA). Understanding promoter regions is crucial in fields like genetics and molecular biology, as they play a key role in regulating gene expression.

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community Minoxidil Sulfate makes everyone a responder

in Research/Science 255 upvotes 1 week ago

Minoxidil sulfate is more effective than regular minoxidil, especially for those with low sulfotransferase levels or scalp sensitivity, but it is unstable unless delivered in a liposomal format. Combining minoxidil with tretinoin can enhance effectiveness, and stopping minoxidil use can lead to rapid hair loss.

community Comprehensive list of Hair loss treatments and your opinion on the best combination to us.

in Technology 6 upvotes 9 months ago

The conversation discusses using oral Minoxidil, topical Minoxidil with RU58841, Finasteride, and serioxyl for hair loss. It also asks for opinions on the effectiveness of other treatments like Setipiprant, Dutasteride, and Spironolactone, and thoughts on HMI-115 and GT20029 trials.

community Adrogens and Covid-19

in Treatment 8 upvotes 4 years ago

The possible increased risk of severe Covid-19 cases in men due to higher androgen levels, and how taking medications such as finasteride, dutasteride, spironolactone, enzalutamide, or canabidiol might help mitigate the severity of the disease.

community Is itching related to hair loss?

in Treatment 54 upvotes 2 years ago

Hair loss, which is sometimes accompanied by itching. Treatments discussed include Minoxidil, finasteride, RU58841 and ketocazole shampoo.

community What else is good. Besides the big 3.

in Chat 36 upvotes 1 month ago

Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

community Finasteride not working after 8 months, need advice please.

in Finasteride/Dutasteride 11 upvotes 2 years ago

Finasteride isn't working after 8 months, and stopping minoxidil led to no regrowth. Advice includes resuming minoxidil, correcting iron deficiency, and continuing finasteride.

community NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress

in Research/Science 14 upvotes 5 months ago

NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.

community 0.5mg Dutasteride promotes more “regrowth” than 5mg oral Minoxidil

in Research/Science 117 upvotes 9 months ago

Dutasteride promotes more hair regrowth than Minoxidil. Users discuss combining treatments for better results and share personal experiences with side effects.

community Why Viagra promotes hair growth like oral minoxidil

in Minoxidil 84 upvotes 2 years ago

How oral minoxidil and topical sildenafil (similar to Viagra) are used for hair growth by increasing blood flow to the scalp, and potential side effects of combining these treatments with other drugs.

community Peppermint Oil Promotes Hair Growth without Toxic Signs -Toxicological Research | Korea Science

in Research/Science 6 upvotes 4 years ago

Peppermint oil promotes hair growth without toxic effects. Treatments discussed include Minoxidil, finasteride, and RU58841.

community Red Ginseng Extract Promotes the Hair Growth in Cultured Human Hair Follicles

17 upvotes 6 years ago

The conversation is about hair loss treatments, specifically discussing the effectiveness of Red Ginseng Extract in promoting hair growth. Other treatments mentioned include Minoxidil, finasteride, and RU58841.

community Apparently onion juice promotes hair growth. I was very skeptical at first but there seem to be a lot of people commenting on this article that have had positive results

14 upvotes 10 years ago

Onion juice is discussed as a potential treatment for hair growth, with many positive user comments. Other treatments mentioned include Minoxidil, finasteride, and RU58841.

community Found it. Sulforaphane, a phytochemical in broccoli sprouts, promotes hair growth (60% regeneration in mice) by accelerating the degradation of DHT.

112 upvotes 7 years ago

Sulforaphane, found in broccoli sprouts, promotes hair growth by degrading DHT. Users discuss its potential benefits and joke about unconventional application methods.

community microneedling, do the gains go away?

in Microneedling 23 upvotes 2 years ago

Microneedling promotes hair growth by increasing circulation and collagen production, with gains potentially lasting longer than those from minoxidil. Some users report sustained results after stopping microneedling, unlike with minoxidil and finasteride.

community Keratin microspheres - breakthrough

in Research/Science 13 upvotes 8 months ago

A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

community PRP for male pattern baldness?

in Treatment 9 upvotes 1 year ago

Hair loss discussion involves PRP (platelet rich plasma) treatment. PRP doesn't stop hair loss, only promotes regrowth; minoxidil is suggested as a better alternative.

community Seriously confused about minoxidil's method of action

in Minoxidil 6 upvotes 2 years ago

The conversation discusses confusion about how Minoxidil promotes hair growth compared to other substances like Menthol, which have similar actions. The user mentions personal positive results with peppermint oil extract and is currently trying L-citrulline for its vasodilation effects.

community Why is dht bad for scalp hair but good for hair on the rest of body?

in Satire 109 upvotes 1 year ago

The conversation discusses why DHT (dihydrotestosterone) negatively affects scalp hair but promotes growth elsewhere on the body. Various opinions include genetic predispositions, differences in hair follicle reactions to DHT, and the potential role of Omega-3 in reducing inflammation and promoting hair health.

community Aveda composition oil helpful or damaging for hair growth?

in Product 4 years ago

A user is questioning if Aveda composition oil promotes hair growth or blocks it, listing its ingredients. They are experiencing severe hair thinning and are unsure if they should continue using the product.

community Does anyone have any experience with Stemoxydine?

in Product 10 upvotes 2 years ago

Using Stemoxydine, a hair growth promoter, in conjunction with Fin and Minoxidil to help counter shedding induced by the latter two treatments. Another user also shared their experience of using Stemoxydine for three months along with dermastamp.

community Thought I would just make this simply post to explain finasteride and minoxidil with an analogy.

in Chat 41 upvotes 1 week ago

Finasteride stops hair loss by blocking DHT, while Minoxidil promotes hair growth by increasing blood flow to hair follicles. Using both can help regrow hair, but results vary by individual.

community Why don't the Nizoral manufacturers promote their product for MPB?

in Ketoconazole 11 upvotes 2 years ago

Ketoconazole is somewhat effective for male pattern baldness (MPB), but the manufacturer promotes it for dandruff instead, possibly because the dandruff market is larger and to avoid confusion among dandruff sufferers without hair loss.

community Polydopamine Synergizes with Quercetin Nanosystem to Reshape the Perifollicular Microenvironment for Accelerating Hair Regrowth in Androgenetic Alopecia.

in Research/Science 13 upvotes 6 months ago

A quercetin-encapsulated and polydopamine-integrated nanosystem (PDA@QLipo) shows promise for treating androgenetic alopecia by reshaping the perifollicular microenvironment, outperforming minoxidil in hair regeneration. The nanosystem promotes cell proliferation, hair follicle renewal, and recovery by scavenging reactive oxygen species and enhancing neovascularity.

community Can Pyrilutamide use stopp Minoxidil gains

in Chat 3 upvotes 7 months ago

The conversation discusses whether using pyrilutamide would interfere with minoxidil's ability to regrow hair, considering pyrilutamide is seen as a maintenance drug that stops shedding, while minoxidil promotes hair growth but causes initial shedding.

community 2 years later I managed to gain some ground (Hyperresponder)

in Progress Pictures 43 upvotes 1 year ago

The user regained most of their hair using Minoxidil, Finasteride, and Dermarolling. They found Dermarolling particularly effective, as it promotes growth factors and improves hair thickness.

community Oral Castor Oil Experiment Day #1

in Minoxidil 8 upvotes 2 years ago

The user is experimenting with taking 1-1.5ml of pure castor oil orally daily as an alternative to minoxidil for hair growth. They aim to find a safer option that promotes overall body and head hair growth without the side effects of minoxidil.

community OMG INTERVIEW W/ DR TSUJI - The GOD of Hair Cloning! MUST WATCH

in Research/Science 21 upvotes 3 years ago

The conversation discusses an interview with Dr. Tsuji about hair follicle stem cell multiplication and the financial challenges of starting human clinical trials. It also mentions the need for funding to secure a patent for a protein that promotes hair growth.

community Expectations control for SCUBE3

in Research/Science 22 upvotes 8 months ago

SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

community Stemoxydine. What is it and should I add it to my regimen ?

in Research/Science 9 upvotes 2 years ago

Hair loss discussion involves treatments like Minoxidil, Finasteride, and RU58841. Stemoxydine may be effective, but results may take at least 3 months due to hair cycle.

community Study published yesterday : "Brassica oleracea extract, glucosinlates and sulforaphane promote hair growth in vitro and Ex vivo"

in Research/Science 32 upvotes 3 years ago

The conversation discusses hair loss treatments, specifically Brassica oleracea extract, glucosinolates, and sulforaphane, and their potential to promote hair growth. Users also mention minoxidil and finasteride as existing treatments.