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      community Finasteride with high estradiol levels

       7 upvotes 2 years ago
      A 22-year-old with high estradiol levels is considering starting finasteride for hair loss. They have an upcoming endocrinologist appointment to discuss whether they should proceed with the treatment.

      community Prolactin and E2 high after finasteride

       18 upvotes 2 weeks ago
      A user experienced libido issues after using finasteride for five months, with elevated prolactin and estradiol levels. The discussion includes differing opinions on whether these symptoms are due to hormonal imbalances or post-finasteride syndrome.

      community My Estradiol was 52 pg/mL (high) should I avoid topical Fin?

       3 upvotes 5 years ago
      The conversation discusses concerns about starting topical finasteride due to high estradiol levels and the potential risk of gynecomastia. Suggestions include using ultrasensitive estradiol tests and considering aromatase inhibitors like zinc, ZMA, or DIM supplements.

      community High estradiol from finasteride

       3 upvotes 4 years ago
      The user experienced high estradiol levels and side effects after stopping finasteride and is concerned about whether these hormonal imbalances are temporary. They are seeking advice on reversing the condition without starting new treatments due to hypersensitivity to finasteride.

      community high estrogen levels after 10month fin

       9 upvotes 3 years ago
      A user experienced high estrogen levels after 10 months of taking 1mg oral finasteride but is happy with hair regrowth. They are considering switching to topical finasteride and are also taking DIM and Zinc supplements.

      community Estradiol mesotherapy / idea feedback

       5 upvotes 1 year ago
      The conversation discusses using estradiol mesotherapy to replicate hormone replacement therapy results while minimizing systemic exposure. It also covers the use of Spironolactone cream, which reportedly has no systemic side effects, and the potential risks of using bicalutamide and Spironolactone in men.

      community Are these a good on, what’s your opinion?

       2 upvotes 1 year ago
      Progesterone, hydrocortisone butyrate, and estrone base are discussed as treatments for hair loss. Topical progesterone and dutasteride are suggested to potentially reverse androgenic alopecia.

      community hight pre-finasteride estrogen levels

      in Finasteride/Dutasteride  1 upvotes 2 years ago
      A user with high pre-finasteride estrogen levels is asking if they need to normalize their hormone levels before starting finasteride and whether they should postpone dermarolling until they begin finasteride. The user is 21.5 years old.

      community What time between shedding phases?

      in Treatment  1 upvotes 1 year ago
      The user is using Dutasteride, Minoxidil, microneedling, RU58841, and tretinoin for hair loss. They are experiencing shedding but notice new hair growth and are curious about the timing of future shedding phases.

      community Breezula phase 3 results said to be released next month

       26 upvotes 1 year ago
      Breezula's phase 3 results are expected soon, with discussions on the effectiveness of androgen receptor antagonists like spironolactone and the potential of GT20029. Users express skepticism about new treatments and discuss the complexities of male pattern baldness, often relying on finasteride despite its side effects.

      community Feel like im not making process. Had insane shed. (Min/Fin/HRT)

      in Progress Pictures  5 upvotes 4 months ago
      The user started using oral minoxidil and estradiol in August 2025, added finasteride in December, and experienced significant hair shedding in February/March. They switched to estradiol injections and are considering their hair washing routine, while another user suggested consulting a dermatologist and possibly trying dutasteride.

      community Breezula Phase III 12-Month Data Released by Cosmo Pharma

       42 upvotes 5 months ago
      Clascoterone 5% topical solution is effective and safe for long-term use in treating male pattern hair loss. Cosmo Pharma aims for EU and US approval, with a potential US release in late 2027 or early 2028.

      community 9 months fin/dut + topical min + estrogen. Doing a happy dance!

       148 upvotes 1 year ago
      The post discusses a user's successful hair regrowth using finasteride, dutasteride, topical minoxidil, and estrogen over nine months. The user, who is male-to-female (mtf), reports significant regrowth and no side effects beyond typical hormone replacement therapy effects.

      community SOS – The cure for women = PREGNANCY

       2 upvotes 7 months ago
      Pregnancy can temporarily reverse hair loss in women, but attempts to mimic pregnancy hormones with treatments like contraceptive pills, spironolactone, estradiol, progesterone, finasteride, and minoxidil have been ineffective. The discussion highlights the need for research into the hormonal mechanisms of pregnancy that affect hair regrowth.

      community 15 Months Ago vs 15 Minutes Ago (Fin + Min + Spiro + E)

       43 upvotes 2 months ago
      The user experienced significant hair regrowth using spironolactone, estradiol, minoxidil, and finasteride while transitioning. They noted reduced libido and increased grogginess as side effects.

      community HRT temple regrowth - 0 months, 3 months, 6 months

       22 upvotes 2 months ago
      The conversation is about hair regrowth progress using hormone replacement therapy (HRT) with Estradiol and Cyproterone, without using Minoxidil. The user shares progress pictures over 0, 3, and 6 months.

      community Why is everyone still arguing about PP405 when clascoterone is already heading toward regulatory submission?

       46 upvotes 1 month ago
      Clascoterone is nearing regulatory submission as a potential new treatment for androgenetic alopecia, with positive Phase III results, while discussions continue about other treatments like PP405, minoxidil, and finasteride. Some users express excitement for clascoterone and Breezula, despite concerns about the effectiveness and practicality of topical treatments.

      community 5 months MTF HRT no min/fin/dut

       35 upvotes 2 years ago
      A 22-year-old trans woman has been on 6mg estradiol enanthate for five months. She reports thicker and healthier hair but not much regrowth yet.

      community Need supplemental products in addition to oral minoxidil and oral dutasteride

       1 upvotes 1 year ago
      The user has been using oral minoxidil and dutasteride for hair loss without success and is considering adding topical 17α-estradiol, Pyrilutamide, Clascoterone, or cetirizine. They have confirmed low serum DHT levels and are exploring additional treatments due to genetic sensitivity to DHT and prostaglandin D2.

      community Very high testosterone and estradiol on finasterid 1 mg. Am I cooked?

       3 upvotes 9 months ago
      A 29-year-old male on 1 mg Finasteride for 3 months has experienced a significant increase in testosterone and estradiol levels, with no major side effects except slightly oilier skin and increased emotional sensitivity. The user is concerned about these hormonal changes and seeks advice, as their general practitioner is not knowledgeable about the issue.

      community Clascoterone - what we have right now

       24 upvotes 6 months ago
      Clascoterone is a topical treatment for androgenetic alopecia, showing modest to moderate hair regrowth, and may be available by 2027-2028. It is considered safer than finasteride, with discussions on its effectiveness compared to RU58841 and pyrilutamide.

      community Finasteride: 1 month microscope update. Before vs After

       27 upvotes 1 year ago
      The user observed some regrowth and longer baby hairs after one month of using finasteride, despite experiencing increased shedding. They noted no side effects except for clear semen.

      community How long are Pelage going to milk the phase 2a results of PP405?

       21 upvotes 7 months ago
      PP405, a potential hair loss treatment, is facing delays in releasing Phase 2 results, causing frustration among users who compare it to past failed treatments. Despite skepticism, some remain hopeful about PP405's future, while others discuss alternative treatments like Clascoterone and its expected market release.