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Clascoterone cream was submitted for review to Health Canada in August 2022, with hopes of approval within 3-6 months. It may potentially enhance finasteride's effects for hair loss treatment.

This conversation is about a user struggling with hair loss who has been told by their barber that minoxidil does not work and the only solution is to accept it. Other users have encouraged them to continue using finasteride and minoxidil, as well as look for another barber, since these treatments are scientifically proven to be effective in combating hair loss.

A 23 year old user's 6 month progress with treatments of 1mg finasteride daily, 5% minoxidil daily, keto shampoo and microneedling once weekly for hair loss. The conversation was encouraging with replies showing admiration for the user's rapid regrowth.

The conversation discusses the theory that scalp fibrosis contributes to male pattern baldness (MPB) by increasing DHT concentration, and mentions treatments like Minoxidil. The user seeks opinions on the theory and the effectiveness of scalp massages.

A user's experience using dutasteride, minoxidil, ketoconazole, vitamin D, scalp massage, exercise, and avoiding vaping and 2-in-1 shampoo/conditioner to treat hair loss; they also discussed the side effects of finasteride.

The conversation discusses the effectiveness of reducing DHT for hair loss treatment and explores alternative approaches like reducing androgen receptor sensitivity. Specific treatments mentioned include finasteride, dutasteride, pyrilutamide (KX-826), GT20029, and RU58841.

Young guys with thick hair asking if they're going bald and people discussing early action for hair loss treatments like Minoxidil and Finasteride. Some users share their positive experiences with these treatments.

A Silicon Valley-backed company aims to cure hair loss. Exciting advancements include mRNA therapies, gene editing, hair cloning, AR degraders, anti-androgens, cell-based rejuvenation, and AI-based drug discovery, with hopes for FDA approval of GT20029 within 10 years.

User experienced gynecomastia from finasteride and found a solution using liposomal topical finasteride. This method minimizes side effects and is effective for hair loss treatment.

Hair loss discussion mentions Verterporfin for scar-free healing and hair follicle regeneration. Human study expected within 2 years.

A 21-year-old male who has been suffering from hair loss since he was 17, and has made great progress with a combination of minoxidil and finasteride topical solutions. They discussed the efficacy of microneedling for sensitive scalps as well.

The user is using topical finasteride and is considering adding minoxidil despite concerns about dependency and side effects. Another user suggests that finasteride alone can reverse hair loss, but adding minoxidil and microneedling may improve results.

The user is seeking an alternative to Rogaine (Minoxidil) due to facial puffiness. Another user responded that Redensyl was ineffective for them.

The conversation discusses using oils like pumpkin seed, rosemary, peppermint, and grape seed oil for hair regrowth, claiming they can be as effective as finasteride or minoxidil without side effects. Some users remain skeptical and prefer proven treatments like minoxidil.

A male with early-stage hair loss experienced severe side effects, including sexual dysfunction from finasteride and increased heart rate and fatigue from high-dose minoxidil, leading to discontinuation of both treatments. He is now relying on DHT-blocking shampoos and awaiting new treatments.

The user updated on their all-natural hair loss protocol, which includes massages, LLLT, Ashwagandha, Supergreens mix, Vitamin D, Castor Oil + DMSO, a specific diet, and headstands. They reported some hair regrowth and improved hair quality, with plans to continue the regimen and monitor results.

The user reported solid results after 5 months of using 1.25mg finasteride daily, with minimal sexual side effects and some hair regrowth at the hairline. They discontinued minoxidil due to its greasy effect on their hair.

PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.

Hair loss treatments like finasteride, minoxidil, and dutasteride work but have side effects. A permanent cure is still not available due to the complexity of hair loss and limited investment.

An 18-year-old began using Finasteride and Topical Minoxidil for hair loss, later switching to Oral Minoxidil and Dutasteride by age 25. The conversation emphasizes early treatment, potential side effects, and differing opinions on medication effectiveness.

Dutasteride at 2.5mg is considered a potential hair loss cure due to its DHT-blocking ability, but there are concerns about side effects and individual responses. Minoxidil, finasteride, and RU58841 are also discussed, with mixed opinions on their effectiveness and safety.

Bryan Johnson uses topical dutasteride, minoxidil, and microneedling for hair loss. Users discuss treatment effectiveness and side effects, debating topical versus oral dutasteride efficacy.

Low-dose oral minoxidil is used for hair loss and does not significantly affect blood pressure but may increase heart rate and cause hypotensive symptoms. Some users experience side effects like palpitations and shortness of breath, while others find it effective; topical minoxidil with tretinoin is also considered.

The conversation discusses the potential of using topical estrogen treatments for hair loss without systemic absorption, highlighting challenges and possible solutions like using estriol. It also mentions other treatments like topical finasteride, microneedling, and scalp massage, while noting the limitations and side effects of current options.

A person improved hair loss from Norwood 3 to Norwood 2 using a topical formula with minoxidil, dutasteride, and tretinoin, plus oral minoxidil and red light therapy. There is skepticism about the treatment's effectiveness and concerns about misleading comparison photos.

Switching from finasteride to dutasteride may be more effective for hair regrowth due to dutasteride's stronger enzyme inhibition, but combining both drugs could enhance results. Some users report better outcomes with dutasteride, while others recommend a gradual transition to prevent potential hair loss.

KX-826 initially improves hair growth but declines after 24 weeks, with mild itching as a side effect. Combining it with minoxidil and finasteride may improve results, but long-term effectiveness is uncertain.

Finasteride and dutasteride can improve skin texture and reduce acne by lowering DHT but do not reverse aging. They may enhance skin and hair health for some, but can also cause side effects like dry skin and sexual dysfunction.

Dutasteride and finasteride can affect libido differently, with some experiencing increased libido and others decreased libido or erectile dysfunction. Dutasteride may increase testosterone levels but can also cause side effects like liver enzyme changes, while topical finasteride may have fewer sexual side effects.

Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.