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Mixing RU58841 directly into minoxidil is discussed, with concerns about storage and potential precipitation when refrigerated. Users share experiences, with some preferring separate applications to prevent breakdown.

User shared 3-month hair loss progress using foam Minoxidil, finasteride, microneedling, and shampoos. They experienced side effects with oral Minoxidil but had success with topical treatments and finasteride.

The user treats hair loss with dutasteride, minoxidil, and tretinoin for about £280 a year by using dutasteride weekly due to its long half-life, while using minoxidil daily. Concerns about the shelf life and absorption of topical treatments were discussed, with some users suggesting alternative sources for these products.

The conversation discusses creating a homemade topical finasteride mix with caffeine, azelaic acid, and copper peptides, using ethanol and glycerin as solvents due to intolerance to propylene glycol. Suggestions include using emulsifiers for mixing and ensuring proper dissolution and stability of ingredients.

Optimal microneedling routine is 1.25mm once a week with Dr Pen 36 needles. Applying Minoxidil right after microneedling may increase systemic absorption risk.

Topical dutasteride 0.05% is more effective for hair growth than oral finasteride 1mg, with minimal DHT reduction. The formulation uses castor oil and MCTs for better absorption but is not widely available until 2028.

Creatine use with finasteride increased DHT levels, possibly affecting hair loss. The user plans to reduce creatine to stabilize DHT and hair shedding.

User shared progress pictures after 9 months of using minoxidil, finasteride, spironolactone, and estradiol for hair loss. Significant regrowth was noted, especially after starting estradiol.

RU58841 solution developed crystals after refrigeration. Letting it reach room temperature and shaking can dissolve the crystals.

The conversation discusses Fevipiprant, an asthma drug that may block CRTH2 and potentially stop male pattern baldness (MPB) without inhibiting DHT. It also mentions the use of finasteride and dutasteride for hair loss.

PP405 shows promise for hair growth with significant results after 4 weeks, but skepticism exists due to its unavailability. Some users are hopeful for its potential, while others express concerns about side effects and market release delays.

PP405 is considered a potential new treatment for hair loss, compared to finasteride and minoxidil. There is skepticism about its effectiveness in humans, with anticipation for more information from an upcoming conference.

The conversation discusses using topical finasteride with propylene glycol, which causes scalp dryness or dandruff. The user also uses Nizoral, Nioxin, and DHT oil, and considers using a scalp conditioner to alleviate dryness.

A new topical treatment, PP405, shows promising results for hair regrowth, potentially outperforming existing treatments like finasteride and minoxidil. However, it may still need to be combined with DHT blockers for optimal results, and its long-term effectiveness remains uncertain.

The conversation is about using distilled water as a solvent for topical finasteride to reduce systemic absorption. The user is considering avoiding ethanol and propylene glycol to achieve this.

Cetirizine 10mg daily reduced hair shedding by 50% and lessened scalp itchiness. The user is considering long-term use for scalp inflammation and hair loss.

The conversation discusses finding a PG-free solvent for dissolving RU58841 in the UK, with glycerin suggested as a potential alternative. Water is also mentioned as a possible option.