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      community I have Post PP405 Syndrome(PPS). Should I start a foundation?

       32 upvotes 1 year ago
      The conversation humorously discusses the fictional "Post PP405 Syndrome" and the idea of starting a foundation or cult around it. It mentions skepticism about the effectiveness of PP405 and jokes about future therapies.

      community Jxl069 (pp405 api) week 8 update

       205 upvotes 1 year ago
      The user shared minimal results from using JXL-069 for hair loss, noting a slight lengthening of vellus hairs and plans to switch to a prodrug variant due to limited effectiveness. They also mentioned using finasteride and minoxidil, which have plateaued in results.

      community Just Minoxidil 5% twice a day for 5 months

      in Progress Pictures  584 upvotes 1 year ago
      Significant hair regrowth was achieved using 5% Minoxidil twice daily and weekly microneedling with a 0.8 mm dermaroller over five months. Finasteride was not used due to concerns about side effects and availability in France.

      community My summation of PP405 - looks promising

       210 upvotes 1 year ago
      PP405 shows promise for hair regrowth by manipulating stem cell characteristics and lactate dehydrogenase, with Phase 2a trials pending. Google Ventures' $15M investment suggests confidence, but results and market availability remain uncertain.

      community Sprinkle that PP405 on my scalp like I sprinkle salt on my stake

       119 upvotes 1 year ago
      PP405 shows promise for hair growth with significant results after 4 weeks, but skepticism exists due to its unavailability. Some users are hopeful for its potential, while others express concerns about side effects and market release delays.

      community PELAGE PHASE 2 TRIALS FOR PP405 - Volunteers Needed

       24 upvotes 2 years ago
      PP405 is a topical gel being tested for hair regrowth in adults with androgenetic alopecia. Volunteers aged 18-55 are needed for a 16-week trial in several US locations.

      community Found a slide summary for PP405

       35 upvotes 5 months ago
      PP405 shows promise in stimulating new terminal hair growth by activating dormant follicles, with no systemic adverse effects observed in a short-term trial. However, long-term efficacy remains unproven, and further trials are needed to confirm its potential as a hair loss treatment.

      community PP405 is nothing but a scam and Pelage know it.

      in Chat  78 upvotes 1 year ago
      PP405 is criticized for overhyped claims and cherry-picked data, with doubts about its effectiveness compared to minoxidil and finasteride. Many users express skepticism, emphasizing the need for more comprehensive trial results.

      community Approve PP405 quickly you coward

      in Satire  193 upvotes 1 year ago
      Pelage Pharmaceuticals is developing PP405, a topical treatment for hair growth, currently in Phase 2a trials. There is skepticism about the company's claims, and no fast-tracking approval timeline has been detailed.

      community PP405 Update and My Take on Pelage

      in Research/Science  86 upvotes 10 months ago
      Pelage Pharmaceuticals raised $120M for their hair loss treatment, PP405, showing strong investor confidence despite limited data. There is skepticism about its efficacy and long-term effects compared to treatments like GT20029.

      community Why doesn't phase 3 of PP405 start straight away?

      in Chat  14 upvotes 8 months ago
      Pelage is delaying the start of phase 3 trials for PP405 to 2026 due to necessary regulatory processes, despite having $120 million in funding. Users discuss the potential of PP405 for hair regrowth, with some expressing skepticism and others hopeful for new treatments like Breezula.

      community If PP405 goes systemic this would be quite catastrophic

      in Research/Science  4 upvotes 1 year ago
      Concerns about the potential systemic effects and safety of PP405 for hair loss, with discussions on its comparison to existing treatments like finasteride and minoxidil. Users express skepticism about untested research chemicals and emphasize the importance of clinical trials to ensure safety and efficacy.

      community PP405 gets its generic name - Suvomipic

       287 upvotes 1 month ago
      Suvomipic, previously known as PP405, is progressing to Phase 3 trials for hair loss treatment. Its effectiveness compared to existing treatments like Minoxidil and Finasteride is still uncertain.

      community PP405 bandwagon, time to resume the hype train.

       164 upvotes 1 year ago
      PP405 shows promise in hair regrowth, potentially outperforming existing treatments like finasteride and minoxidil, with significant results in just four weeks. The treatment is still in early stages, with further trials needed to determine its long-term effectiveness and optimal dosage.

      community Pp405 full presentation on new topical

       106 upvotes 5 months ago
      A new topical treatment, PP405, shows promising results for hair regrowth, potentially outperforming existing treatments like finasteride and minoxidil. However, it may still need to be combined with DHT blockers for optimal results, and its long-term effectiveness remains uncertain.

      community PP405 2a study was a safety study. Some rational explaining.

       22 upvotes 1 year ago
      The conversation discusses the safety study of PP405, emphasizing that early trials focus on safety rather than efficacy, and that any efficacy data from such a short study should be viewed skeptically. It also highlights that the information released is primarily for securing funding, and that meaningful efficacy results are expected in later phases.

      community If PP405 doesn't work then why would Pelage continue with trials?

       44 upvotes 1 month ago
      PP405 is still undergoing trials despite skepticism about its effectiveness. Some believe it shows potential for hair regrowth, possibly in combination with other treatments like minoxidil or finasteride, while others are doubtful due to past disappointments with similar products.

      community PP405 (Non) Update - Feb 2025

       36 upvotes 1 year ago
      The conversation discusses the delay in the PP405 Phase 2 study results, now expected by the end of 2025, and skepticism about research practices. There is also mention of optimism for Amplifica's AMP303 and a topical treatment in early testing.

      community The amazing fast pace of PP405.

      in Chat  327 upvotes 11 months ago
      PP405 is a new hair loss treatment advancing quickly in trials, generating excitement and skepticism about its effectiveness and marketing claims. Some see it as a potential alternative to minoxidil and finasteride, but concerns about long-term effects and the need for DHT blockers persist.

      community It looks like Pelage are giving hints that PP405 is a game changer

      in Chat  239 upvotes 5 months ago
      PP405 is seen as a potential breakthrough for converting vellus hairs to terminal hairs, with users expressing both hope and skepticism. It is compared to treatments like minoxidil and finasteride, with discussions on side effects and marketing concerns.

      community How long are Pelage going to milk the phase 2a results of PP405?

       21 upvotes 7 months ago
      PP405, a potential hair loss treatment, is facing delays in releasing Phase 2 results, causing frustration among users who compare it to past failed treatments. Despite skepticism, some remain hopeful about PP405's future, while others discuss alternative treatments like Clascoterone and its expected market release.

      community Update on PP405 Trails - Pelage

       14 upvotes 7 months ago
      The conversation discusses interest in participating in PP405 trials for hair loss treatment, with users expressing uncertainty about eligibility due to location. Participants are eager for updates and willing to pay for shipping if trials are limited to America.