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Glossary Polysorbate 80

nonionic surfactant used to mix oil and water

Polysorbate 80, also known as Tween 80, is a nonionic surfactant and emulsifier commonly used in pharmaceuticals, cosmetics, and food products to help mix ingredients that typically don't blend well, such as oil and water. In the context of hair care, it is sometimes included in formulations to improve the distribution of active ingredients and enhance the texture of the product.

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community I want to prepare a Topical Catalase with Phosphate Buffered Saline Solution.

2 upvotes 5 months ago

The conversation discusses creating a topical catalase solution with phosphate buffered saline, glycerin, and polysorbate 20 for hair loss treatment. The user seeks advice on preparing this solution.

community Best way to go about making a DIY topical fin for someone who's allergic to PG?

1 upvotes 5 months ago

A user allergic to propylene glycol seeks alternatives for a DIY topical finasteride solution, considering glycerin or glycerol-based vehicles. Another user suggests a recipe using propanediol, DMSO, MCT oil, and peppermint oil, incorporating minoxidil, dutasteride, and finasteride.

community Topical Minoxidil foam + Finasteride

in Finasteride/Dutasteride 1 upvotes 2 years ago

The conversation discusses using minoxidil foam as a solvent for topical finasteride. Ingredients of minoxidil foam include butane, cetyl alcohol, glycerin, and purified water.

community Diluting 0.05% topical finasteride serum/oil

1 upvotes 3 years ago

The user wants to reduce their dose of topical finasteride to 0.1-0.2mg and is considering mixing 0.2ml of their current finasteride + minoxidil serum with 0.8ml of a minoxidil-only serum for better scalp coverage. They are asking for advice on whether this method is effective or if there's a better way to dilute the finasteride solution.

community Can i dissolve finasteride pills in this?

3 upvotes 3 years ago

The conversation is about finding cheaper alternatives for hair loss treatments. Specific treatments mentioned include finasteride and L'Oréal Paris Elvital Hyaluron Plump Leave-In Spray.

community Topical Finasteride with rogain foam as solvent

1 upvotes 4 years ago

The conversation discusses using Rogain foam as a solvent for topical finasteride due to an allergy to propylene glycol. The foam's ingredients, including alcohol SD 40B, are considered suitable for dissolving finasteride for easier application without skin irritation.

community Zinc Pyrithione for pattern hair loss.

4 upvotes 5 years ago

Zinc pyrithione and ketoconazole shampoos may help reduce hair loss by removing DHT from the scalp. Users discuss various treatments, including minoxidil, finasteride, and non-pharmaceutical options like castor oil and dermarolling.

community Is finasteride mixable with this serum?

in Finasteride/Dutasteride 1 upvotes 1 year ago

The conversation discusses mixing finasteride (Essengen-F) with a multi-peptide serum for hair density. The main concern is whether these products can be used together safely.

community Anyone else on their first couple weeks of Propecia (Finasteride) feel like little hair farmers?

138 upvotes 6 years ago

Taking steps to improve hair loss through treatments such as finasteride, minoxidil and ketoconazole. People discussed their experiences and shared a sense of satisfaction from taking action to improve their condition.

community If you had to abandon DHT blockers, what’s next?

64 upvotes 8 months ago

Users discuss alternatives to DHT blockers for hair loss, suggesting minoxidil, microneedling, natural DHT blockers, and scalp massages. Some explore RU58841, ketoconazole, hair transplants, and hair systems due to side effects from finasteride and dutasteride.

community Creating Custom Topicals: A Guide (2025 Edition)

27 upvotes 10 months ago

Creating custom topical treatments for hair loss using minoxidil, finasteride, and RU58841. It includes recipes and instructions for home preparation, focusing on cost savings and customization.

community Nice product I discovered, thought I would share.

in Treatment 456 upvotes 1 year ago

A product that makes hair look thicker and healthier without promoting regrowth. Discussions include treatments like minoxidil, finasteride, red light therapy, and a serum with caffeine and peptides, with mixed effectiveness opinions.

community Does anyone know the chemical formula for pelage pp405?

15 upvotes 1 year ago

The conversation discusses the lack of public information on the chemical structure of PP405, a hair loss treatment, and the challenges of synthesizing it without a patent. It also explores a patent related to hydrogen-based topical formulations for reducing oxidative stress and inflammation.

community Finasteride can revive up to 7 year old dead hair

in Research/Science 188 upvotes 1 year ago

Finasteride and minoxidil can revive hair dormant for up to 7 years, with microneedling enhancing regrowth. Users report significant hair regrowth even after long periods of baldness.

community Peptides that Stop Hair Loss? | In-depth Literature Review Video

76 upvotes 2 years ago

Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.

community carriers other than PG for ru58841 ? Help !!

5 upvotes 1 year ago

The user is seeking alternatives to propylene glycol and glycerin for mixing with RU58841 due to allergies and greasiness. Suggestions include reducing glycerin and considering stemoxydine as a solvent.

community Making PG free solution at home

1 upvotes 2 years ago

A user wants to make a solution for RU58841 and finasteride powder using only glycerin and asks if ethanol is necessary. They are seeking advice on whether glycerin alone is sufficient.

community Je peux utiliser ce produit seul comme solvant pour dilluer mon finasteride ?

5 months ago

OP asked if a product from Amazon is sufficient to dilute finasteride. A user advised against using propylene glycol alone, suggesting a pre-made solution instead.

community Topical finasteride making. Powder not disolving

4 upvotes 3 years ago

OP is trying to dissolve finasteride powder for a topical solution but faces issues with it not dissolving properly in ethanol or water. Users suggest methods like using a magnetic stirrer, shaking the mixture, or filtering out fillers, with some noting that finasteride is soluble in alcohol.

community PG free Ru58841 solvent in the UK

2 upvotes 3 weeks ago

The conversation discusses finding a PG-free solvent for dissolving RU58841 in the UK, with glycerin suggested as a potential alternative. Water is also mentioned as a possible option.

community For pg free minoxidil, why not use propanediol instead of glycerin?

2 upvotes 4 months ago

The conversation discusses using propanediol as an alternative to glycerin in PG-free minoxidil for better absorption. The user also plans to try nanoxidil, which may absorb more easily due to its smaller molecule size.

community Topical finasteride in liposomal formulation

6 upvotes 6 years ago

Topical finasteride in a liposomal formulation reduces systemic absorption compared to ethanol solutions. The user is seeking sources for such products, noting that popular options like morr-f are not liposomal.

community Why don't do it yourself topical solutions not talk about ethosomes as delivery mechanism?

4 upvotes 10 months ago

Ethosomes are suggested as an effective delivery method for topical finasteride solutions, requiring the addition of a phospholipid like soya lecithins. The user questions why do-it-yourself solutions don't commonly use ethosomes despite their potential benefits.

community The best Ethanol/Propylene Glycol ratio for home made topical finasteride?

4 upvotes 2 years ago

The conversation discusses the best ethanol and propylene glycol ratio for homemade topical finasteride, with a focus on absorption and drying issues. The user shares their experience using a 50% propylene glycol, 30% ethanol, and 20% water solution, and considers adjusting the ethanol content for better results.

community Propylene Glycol vs Glycerin in topical finasterside?

2 upvotes 10 months ago

Switching from propylene glycol to glycerin in topical finasteride may reduce systemic absorption and side effects while maintaining local scalp DHT suppression. Concerns exist about glycerin's ability to deliver the full dose to hair follicles.

community Solvent for topical fin with low absorption

2 upvotes 2 years ago

The conversation is about using distilled water as a solvent for topical finasteride to reduce systemic absorption. The user is considering avoiding ethanol and propylene glycol to achieve this.

community Be careful about using non-PG based alternatives of Minoxidil (mathematically speaking, haven’t seen much practical studies)

in Research/Science 7 upvotes 1 month ago

Minoxidil formulations often use propylene glycol (PG) for stability and effectiveness, but PG-free alternatives like foams and PEG-based solutions can also be effective with less irritation. Concerns exist about the quality of PG-free minoxidil from lesser-known brands, especially from India, due to potential manufacturing issues.

community Propylene glycol vs ethyl alcohol(70% or 96%) for topical finasteride solution. Pros and cons?

4 upvotes 2 years ago

The conversation discusses the pros and cons of using propylene glycol versus ethyl alcohol in topical solutions for finasteride and minoxidil. It questions why propylene glycol is commonly used and whether ethyl alcohol might be a better option.

community Diy dutesteride please help MCT oil or PG?

1 upvotes 9 months ago

A user is making their own dutasteride solution using MCT oil but is concerned about its effectiveness and bioavailability. They are considering using propylene glycol or adding ethanol for better results, while others suggest the current dosage might be excessive.

community Anyone knows if koshine kx-826 has propylene glicol?

11 months ago

Koshine KX-826 has different versions, and the green version uses a plant-based carrier that may be less irritating for those sensitive to propylene glycol. Users report irritation with some versions of KX-826.