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GlossaryPlacebo Group

group receiving an inactive substance to compare treatment effects

A Placebo Group is a set of participants in a clinical trial who receive a placebo—a substance with no therapeutic effect, often a sugar pill—rather than the active treatment being tested. This group serves as a baseline to compare the effects of the actual treatment, helping researchers determine whether the treatment's effects are due to the treatment itself or other factors. This is also known as a Control Group in many studies.

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community 35% regrowth brothers and sisters! More effective than Minox and Fin?

in Treatment 107 upvotes 6 years ago

A double-blind clinical study that found ingestion of tocotrienols resulted in a 34.5% increase in hair regrowth compared to the placebo group, and discussion about potential side effects and cost of supplementation with vitamin E pills. The conversation noted that it may be more effective than commonly used treatments like minoxidil and finasteride.

community TDM-105795 phase 2 results are in!

in Research/Science 28 upvotes 10 months ago

TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.

community Pyrilutamide phase III clinical trial results released

in Research/Science 31 upvotes 1 year ago

Pyrilutamide did not show effectiveness in regrowing hair compared to a placebo, but it may still help maintain existing hair by preventing DHT from causing follicle miniaturization. Some users believe it could be beneficial when used with other treatments like minoxidil, finasteride, and dutasteride.

community Kintor has released an investor relations memo regarding Chinese Phase III trials for Pyrilutamide

in Update 51 upvotes 1 year ago

Kintor's Pyrilutamide (KX-826) showed hair growth in Chinese Phase III trials but did not significantly outperform placebo. The treatment was safe with no major adverse reactions reported.

community Breaking hair loss news! GT20029 is a resounding success!

in Product 132 upvotes 8 months ago

GT20029, a new hair loss treatment, shows promising results but only a slight improvement over placebo. People are cautiously optimistic, discussing its potential and combining it with existing treatments like Minoxidil and Finasteride.

community Kintor Pharma Announces Successful Completion of Phase II Clinical Trial of KX-826 for Treatment of Androgenetic Alopecia in the US

in Research/Science 122 upvotes 1 year ago

Kintor Pharma announced successful Phase II trial results for KX-826 in treating hair loss, showing it's comparable to finasteride and can be used with it. Some participants saw a 10 hair/cm^2 increase, which is considered a good outcome at the low dose used.

community Has pyrilutamide worked for anybody?

in Product 1 upvotes 4 months ago

The post discusses the effectiveness of pyrilutamide for hair loss. The user maintains hair with alfatrodial, fluridil, minoxidil, and keto shampoo but is seeking a simpler and cheaper alternative.

community Saw palmetto, eucapil and micro needeling

in Treatment 7 upvotes 2 years ago

User noticed receding temples, used minoxidil and microneedling with positive results. Added saw palmetto and eucapil, experienced shedding and thinner hairline, but no side effects.

community ladies and gentlmen, vitamin E is your hair follicles second best friend

in Treatment 51 upvotes 2 years ago

Vitamin E is suggested as beneficial for hair follicles. Some users question the dosage and effectiveness, while others share positive experiences with vitamins.

community Puffy eyes / fluid retention on Oral Minoxidil? Add an ACEi or ARB! NOT MEDICAL ADVICE

in Minoxidil 8 upvotes 3 years ago

Oral Minoxidil can cause puffy eyes and fluid retention. Adding an ACE inhibitor or ARB, like Telmisartan, may help mitigate these side effects.

community Have people with aggressive balding genetics genuinely had any results after applying any natural remedies ie:rosemary oil,coconut oil,Onion Juice etc

in Research/Science 42 upvotes 1 year ago

Natural remedies like rosemary oil, coconut oil, and onion juice are generally seen as less effective compared to medical treatments like finasteride, minoxidil, and microneedling. Some users believe natural oils can help, but modern medicine is often more reliable.

community Currently participating in the Extended Phase III clinical trial of Pyrilutamid in China

in Technology 81 upvotes 1 year ago

A user from China is participating in a clinical trial for Pyrilutamid, a potential hair loss treatment originally developed for prostate cancer. They've experienced no side effects except initial scalp itchiness, and will share results after the year-long trial.

community CASSIOPEA ANNOUNCES VERY POSITIVE PHASE II TWELVE MONTHS RESULTS FOR BREEZULA® (CLASCOTERONE) IN TREATING ANDROGENETIC ALOPECIA

in Update 161 upvotes 5 years ago

Clascoterone (Breezula) showed positive results for treating hair loss without affecting cortisol levels. Opinions vary, with some users optimistic about its potential and others critical of its effectiveness compared to existing treatments like finasteride.

community Consensus on pyrilutamide? i want to start but not sure…

in Research/Science 6 upvotes 4 months ago

The post and conversation discuss the effectiveness of pyrilutamide for hair loss, with comparisons to finasteride and RU58841. Users express skepticism due to failed trials and high costs, with some waiting for more data before trying pyrilutamide.

community Why TDM-105795 is not much talked about like GT20029 and HMI 115 despite having far better Trial results?

in Research/Science 36 upvotes 7 months ago

TDM-105795 showed better efficacy and safety in trials for hair loss, with a higher hair count improvement compared to GT20029 and HMI 115, but it's not as widely discussed. The user is questioning why this is the case.

community Target Area Hair Count (TAHC) increase comparasion of all future treatments in clinical trial phases

in Research/Science 37 upvotes 8 months ago

Finasteride, Minoxidil, Bioneer CosmeRNA, Technoderma, Kintor, Hope, Breezula, and Follicum treatments showed increases in hair count, with Technoderma showing the highest increase at 24.3 hairs/cm². Amplifica has not yet published results.

community Pyrilutamide phase 3 results and maintenance?

in Research/Science 4 upvotes 8 months ago

Pyrilutamide phase 3 results showed little to no significant hair regrowth, but may be sufficient for maintaining current hair density. The user is unsure due to lack of recent discussions on pyrilutamide.

community Further prolactin research....

in Research/Science 6 upvotes 11 months ago

HMI 115 did not work as expected for hair regrowth in humans, unlike in macaque monkeys. There is anticipation for further research on prolactin's role in hair loss, with expectations that pharmaceutical companies will likely solve this before universities.

community Phase 3 of pyrilutamide (kx-836) analysis of the efficacy

in Research/Science 11 upvotes 1 year ago

The conversation discusses the less impressive results of Pyrilutamide (kx-836) in phase 3 compared to phase 2, with a suggestion that a longer study might show more significant results. One user reports personal success with Pyrilutamide, experiencing no further hair loss and gradual regrowth.

community Has anyone tried the New Nordic Hair Gro tablets?

in Product 2 upvotes 1 year ago

The conversation discusses the effectiveness of New Nordic Hair Gro tablets for hair loss. Specific treatments mentioned include Minoxidil, Finasteride, and RU58841.

community 48M, 11 month progress, 1MG finasteride only

in Progress Pictures 627 upvotes 1 year ago

A 48-year-old man's 11-month progress using 1mg finasteride for hair loss treatment, with significant improvement and no side effects. Other users share their experiences, with some also seeing positive results, while others have not been as successful.

community I have a hard time believing that creatine overpowers fin/dut

in Finasteride/Dutasteride 109 upvotes 1 year ago

The conversation is about whether creatine causes hair loss in individuals who are taking finasteride or dutasteride for hair loss. Some users report experiencing hair loss when taking creatine, while others do not. There is no consensus on the issue.

community Thoughts on this procyanidin B2 supplement?

in Product 6 upvotes 1 year ago

User found 15% procyanidin B2 supplement and asks if it's legit. Recommended dosage is 400-600mg daily, similar to study, and user wonders if it's effective for hair loss.

community PSA: Most men who stay on Fin will see the sexual side effects go away. Stop the fear mongering

in Finasteride/Dutasteride 191 upvotes 2 years ago

Finasteride can cause sexual side effects in less than 2% of men, but these often disappear over time, even if the treatment continues. Some users report persistent side effects, while others experience no issues or only temporary ones.

community Anyone here get results from topical melatonin?

in Research/Science 11 upvotes 3 years ago

A user has been using finasteride and minoxidil for hair loss but is experiencing increased shedding and is considering using topical melatonin with a product called Rizn. Another user is skeptical about the effectiveness of topical melatonin due to issues with the research and lack of replication of results, while a third user expresses interest in the outcome of using Rizn after not seeing results from topical finasteride and minoxidil.

community Why Didn't the Pumkin Seed Oil Study Get More Attention?

in Question 70 upvotes 5 years ago

Pumpkin seed oil showed a 40% increase in hair count, but its effectiveness is questioned due to other ingredients in the supplement. Users discuss its potential compared to finasteride, with some expressing skepticism and others showing interest.

community Thoughts on Finasteride and Sexual Side Effects

in Finasteride 51 upvotes 5 years ago

A user discusses starting finasteride for hair loss despite concerns about potential sexual side effects, emphasizing the psychological factors involved. Other users share mixed experiences, with some reporting no side effects and others experiencing issues.

community [Discussion] Interesting read on Vitamin E for hair loss I found

in Advice 16 upvotes 6 years ago

The conversation discusses using Vitamin E, Minoxidil, finasteride, and RU58841 for hair loss treatment. The link provided offers more information on the benefits of Vitamin E for hair loss.

community Red Ginseng Extract Promotes the Hair Growth in Cultured Human Hair Follicles

17 upvotes 6 years ago

The conversation is about hair loss treatments, specifically discussing the effectiveness of Red Ginseng Extract in promoting hair growth. Other treatments mentioned include Minoxidil, finasteride, and RU58841.

community What about botox injections on the scalp?

in Research/Science 6 upvotes 1 year ago

Botox injections on the scalp may help with hair loss, as one small study showed improvement in 8 out of 10 subjects. Treatments mentioned include Minoxidil, finasteride, and RU58841.