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      community Will we really be able to use pp405?

       4 upvotes 11 months ago
      People are skeptical about the effectiveness and availability of pp405 for hair regrowth, suggesting to use finasteride and minoxidil in the meantime. Some believe pp405 could offer significant regrowth, but it may take years before it's available.

      community Losing Hair on Dutasteride? You might have LPP

       96 upvotes 1 year ago
      Men with hair loss might have lichen planopilaris (LPP), which can mimic androgenetic alopecia, leading to misdiagnosis and ineffective treatment with finasteride or dutasteride. Proper diagnosis, including biopsies, is crucial to distinguish between androgenetic alopecia and conditions like LPP.

      community Any chemists want to manufacture PP405 / JXL069? (Steps inside)

       89 upvotes 10 months ago
      The conversation discusses the synthesis and potential use of JXL069 and PP405 for hair loss treatment, with skepticism about their effectiveness and concerns about safety. Users mention that JXL069 has shown no results in hair growth, and there is confusion about its identity and effectiveness compared to PP405.

      community Tresless Bingo - This sub in a nutshell

       269 upvotes 1 month ago
      The conversation humorously critiques common hair loss discussions, mentioning treatments like Minoxidil, finasteride, and RU58841. It highlights confusion over progress pictures, pet safety concerns, and unrealistic expectations for new treatments.

      community The expected timeline for PP405 - Next update at AAD Annual Meeting in March 2026 ?

       34 upvotes 8 months ago
      A new hair loss treatment, PP405, showed promising Phase 2a results with 31% of patients experiencing over 20% hair density increase without systemic absorption, avoiding hormonal side effects. The treatment is expected to be expensive, with Phase 3 trials starting mid-2026, and there is skepticism about the data's strength.

      community One month Umbrella Labs PP405 results.

       55 upvotes 9 months ago
      The user tried a product labeled as PP405 from Umbrella Labs for hair loss but saw no changes, and it was revealed to be a fake or misidentified product. The user is also using finasteride, minoxidil, and other treatments but is still experiencing hairline issues.

      community Has anyone tried CB-01-03 aka Clascoterone?

       2 upvotes 6 months ago
      Clascoterone, a topical anti-androgen, is generating interest for potentially fewer systemic side effects. Users are curious about its effectiveness and details like concentration and duration of use.

      community OFFICIAL Multi-Center Verteporfin Trial Recruitment

       251 upvotes 1 year ago
      Recruitment for a verteporfin trial and a separate hair cloning trial using verteporfin and other methods is underway, with locations in Jordan, NYC, Beverly Hills, and Memphis. Dr. Bloxham is conducting the hair cloning trial, and interested participants are encouraged to contact him directly.

      community Locklabs + Dutasteride Formula

       1 upvotes 8 months ago
      The conversation discusses the effectiveness and value of a Locklabs pill containing finasteride, minoxidil, biotin, and a low dose of dutasteride for hair loss. The user is uncertain if the .1mg dutasteride dosage is sufficient and worth the cost.

      community Thoughts on new drug PP405? Already reached phase 2

       26 upvotes 1 year ago
      PP405 is a new drug in Phase 2 trials for hair loss, generating cautious optimism among users. Some users are currently using finasteride and experiencing side effects, while others are skeptical about unapproved products being sold.

      community My Idea for a possible new hairloss treatment

       53 upvotes 6 years ago
      Exploring a potential hair loss treatment using the enzyme AKR1C2 to locally reduce DHT levels. Challenges include enzyme delivery through the skin and high production costs, with gene therapy or stem cells suggested as future alternatives.

      community Has anyone ordered JXL-069 (grey market PP405)?

       53 upvotes 1 year ago
      People are discussing JXL-069 (PP405) for hair loss, with some experimenting with a 0.05% topical gel. Concerns about safety and efficacy persist due to limited testing and lack of official approval.

      community PP405 Hairloss Reversal and Hairline Restoration

       5 upvotes 7 months ago
      PP405 may induce new hair growth but cannot revive completely dead follicles, and its effectiveness on hairlines is uncertain. It is expected to be available by mid-2028, but users are advised to manage expectations and consider using other treatments like minoxidil and finasteride.

      community Tressless ChatGPT AI is GOAT..

       30 upvotes 2 years ago
      Minoxidil, finasteride, and RU58841 are discussed as treatments for hair loss. Users find ChatGPT a helpful tool for researching these treatments.

      community Rate my stack! (Using a nuclear protocol)

       17 upvotes 5 years ago
      A hair loss regimen involving Dutasteride, Oral Minoxidil, Mesotherapy, Topical Minoxidil/Finasteride, RU58841, Alfatridiol, Microneedling, LLLT, Keto shampoo, Vitamin K/D/Fish oil/Borage Oil/MSM, Oral Castor oil and Niacin. It also mentions products that have been dropped from the regimen due to not being worth the hassle or messing with libido.

      community Just started ru58841, ask me anything.

      in Research/Science  14 upvotes 8 months ago
      The conversation discusses a hair loss treatment regimen including oral dutasteride, oral minoxidil, tadalafil, and the recent addition of RU58841. The user shares experiences with these treatments, noting significant hair regrowth and stabilization, and discusses the cost and preparation of RU58841.

      community Is this regrowth? ketoconazole

      in Is this regrowth?  13 upvotes 1 year ago
      The conversation is about hair regrowth treatments, including ketoconazole, vitamins, fish oil, collagen, pumpkin seed oil, rosemary, and dermal rolling. Users suggest trying finasteride and intense weight training to enhance results.

      community Best place to buy Alfatradiol if you live in Canada (Not ebay)

       4 upvotes 5 years ago
      People are discussing where to buy Alfatradiol in Canada, avoiding eBay due to past issues. They share experiences and links to potential sellers, with some users noting the lower potency of available Alfatradiol products.