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      community Losing gains from 7 months of oral min, fin, dut.

      in Update  66 upvotes 11 months ago
      A user reported losing hair after 7 months of using oral minoxidil, finasteride, and dutasteride, but others reassured that this is likely just a shedding phase where old hairs fall out to make way for new growth. Some users experience sheds every 7-8 months and suggest staying consistent with treatment.

      community From n5 to n3 going n2 , 1 year 2mos progress

      in Progress Pictures  373 upvotes 1 year ago
      The user improved their hair loss from stage 5 to stage 3 using Minoxidil, Finasteride, and a Dermapen. They saw results after 6 months, experienced a shedding phase, then saw more gains, advising others not to be discouraged during the shedding phase.

      community Daily scalp massages lead to more hair loss or not?

      in Treatment  10 upvotes 1 year ago
      The user applies castor oil and uses silicon scalp massagers daily, questioning if the massages cause more hair loss or if the hairs would fall out naturally. They believe the hairs are in the telogen phase and would shed regardless of the massage.

      community Finasteride shed is crazy at 7 months

      in Finasteride/Dutasteride  30 upvotes 1 year ago
      The conclusion of the conversation is that experiencing shedding while using finasteride and minoxidil is a common occurrence, and it is likely a part of the hair growth cycle. Many users have reported regrowth and improvement in their hair density after the shedding phase.

      community Hair Transplant result after one week

      in Progress Pictures  588 upvotes 1 year ago
      The post is about a user's hair transplant results after one week, with 4000 grafts implanted. The conversation includes discussions about the healing process, shedding phase, and the number of grafts used.

      community Stemoxydine- lifelong use? curious.

      in Treatment  6 upvotes 1 year ago
      The conversation discusses whether stemoxydine needs to be used for life for hair loss treatment. One user suggests that stemoxydine does not require lifelong use and can make hair exit the resting phase faster, but the benefits may be temporary.

      community Update to fin 0.25 mg, 4x/week

      in Progress Pictures  64 upvotes 1 year ago
      User reported initial hair regrowth with 0.25 mg finasteride taken four times a week, experiencing a second shedding phase, and no side effects. They also mentioned using RU58841 without success and plan to stop after a year.

      community HMI-115 question about potential earliest access

      in Research/Science  9 upvotes 1 year ago
      Hair loss treatments discussed include Minoxidil, Finasteride, and RU58841. HMI-115, a monoclonal antibody drug, is in phase 1 and 2 trials for different conditions, but its availability on the gray market is unlikely due to high production costs.

      community Can HMI-115 reverse miniaturization?

      in Research/Science  11 upvotes 1 year ago
      HMI-115, a potential treatment for hair loss that can reverse miniaturization and make individual hairs thicker, as evidenced by data from macaques given the treatment and one subject in the phase I trial.

      community What ever happened to pyrilutamide?

      in Technology  49 upvotes 1 year ago
      Pyrilutamide, a potentially effective hair loss treatment; other topical treatments like RU58841 and CB-03-01 that may have fewer side effects than Pyrilutamide; and the Phase 3 clinical trials of Pyrilutamide, which is likely to be approved by the FDA soon.

      community HLT Megathread on HMI-115 (key takeaways in comments)

      in Research/Science  38 upvotes 1 year ago
      HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

      community 4 months Oral Minoxidil 1.25 mg Daily (33 M)

      in Progress Pictures  520 upvotes 1 year ago
      This user, "ediblediety", has been taking oral minoxidil (1.25 mg daily), keto shampoo and occasional derm-rolling for 4 months to treat their hair loss, and they have experienced a shedding phase after the first few weeks of use. They report improvements in the thickness of their facial and body hair, but note that this may be daunting to women.

      community When will GT20029 become available for group buy?

      in Research/Science  7 upvotes 1 year ago
      The conversation discusses the potential availability of GT20029 for hair loss treatment, with one user noting promising Phase 1 results and inquiring about gray market access. Another user humorously suggests it will take 50 years to become available.

      community discouraged about pyrilutamide

      in Research/Science  11 upvotes 2 years ago
      Discouragement regarding Pyrilutamide, a drug in development for hair loss, and the potential side effects of Finasteride. People discussed anecdotal experiences with Pyrilutamide as well as suggestions to wait out Phase 3 trials before making any conclusions.

      community Twist1 Group Buy: Yes it’s that easy

      in Research/Science  39 upvotes 2 years ago
      A group buy for testing a compound targeting Twist1 protein as a potential hair loss treatment. Inhibiting Twist1, which keeps hair follicles in growth phase, may prevent hair loss with minimal side effects.

      community My 1 year crown transformation (2nd hair transplant)

      in Progress Pictures  3 upvotes 5 months ago
      A user shared their 1-year crown transformation after a second hair transplant with 4000 grafts, using finasteride, minoxidil, and vitamins. Another user commented that while the crown has filled in, they expected more coverage from 4000 grafts and suggested a possible shedding phase.

      community 1 year of min+fin+ketoconazole

      in Progress Pictures  1056 upvotes 7 months ago
      The user has been using minoxidil daily, finasteride three times a week, and ketoconazole 1-3 times a week for a year to treat hair loss, resulting in noticeable hair regrowth at the hairline and temples, with minor side effects like itching and dandruff. They started with minoxidil a month before the other treatments and experienced an initial shedding phase for about six weeks.

      community Keto 2% halted my insane shed immediately

      in Ketoconazole  57 upvotes 7 months ago
      Ketoconazole 2% shampoo stopped a user's severe hair shedding after just two uses, a result not achieved by finasteride or oral minoxidil. Some users suggest the shampoo's anti-androgenic properties may help with hair loss, while others think the shedding might have stopped naturally or due to the end of a shedding phase.

      community Progress - Min, Fin, and Nizoral.

      in Progress Pictures  342 upvotes 10 months ago
      The user shared progress photos showing hair regrowth after using Minoxidil, Finasteride, and Nizoral since mid-2023, and plans to replace derma rolling with Tretinoin. They discussed their routine, the initial shedding phase, and their experience with side effects, while others commented on the visible improvement.

      community Finally decided to post / Started June 26th

      in Progress Pictures  11 upvotes 10 months ago
      The user started hair loss treatment on June 26th using 1.25mg finasteride, 1ml 5% minoxidil twice a day, derma rolling every 1.5 weeks, and 2% ketoconazole foam twice a week. They experienced significant hair growth in the first four months, with thicker hair and improved hairline, but had a rough shedding phase in November.

      community 6.5 Month Progression 33/Female

      in Female  47 upvotes 1 year ago
      Maintaining scalp hair and minimizing shedding, treatments used such as Procapil, supplements, topical caffeine, topical estrogen, and scalp massage; suggestions for anagen extenders or pharmaceuticals to help with a short anagen phase.

      community Is there any chance of improvement?

      in Minoxidil  7 upvotes 2 years ago
      A 19-year-old experiencing severe hair loss since 16 is using a treatment regimen of 5% minoxidil, 0.1% finasteride topical solution, 3% procapil hair serum, and 0.5 mg dutasteride daily. They are concerned about the effectiveness and potential shedding phase, with advice suggesting noticeable changes in 6 to 8 months.

      community Who said GT20029 would be applied only few times per month?

      in Research/Science  10 upvotes 2 years ago
      The conversation discusses the safety and effectiveness of a hair loss drug, GT20029, and the possibility of infrequent application, with users hoping for once-daily use and speculating on the drug's duration of effect on the scalp. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.