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GlossaryPharmacotherapy (Pharmacological Interventions)

use of medications to treat medical conditions

Pharmacotherapy, also known as drug therapy or medication therapy, involves the use of medications to treat various medical conditions. This approach leverages the therapeutic effects of drugs to manage symptoms, cure diseases, or prevent health issues, and is often tailored to individual patient needs based on factors like age, weight, and specific health conditions.

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community Update about Hair Follicle Glucose Metabolism: New Clinical Data Collection with Ex-President Of American Board Of Hair Restoration Surgery.

in Research/Science 41 upvotes 4 months ago

David Barreto shared that a London-based research group is conducting a 12-month trial for a new nutraceutical treatment for pattern hair loss, designed with Dr. Carlos Puig. The trial aims to provide robust data, with results expected in 1-2 years, potentially representing a significant advancement since finasteride’s introduction in 1997.

community Most Recent Interesting Hairloss Studies: 10% Minox vs 5% Minox / Radio Rrequency Treatment for AA / Topical Ketoconazole / PRP+Minox vs Minox vs PRP / Alopecia as a systemic disease

in Treatment 90 upvotes 4 years ago

Treatments for hair loss, such as topical minoxidil, platelet-rich plasma therapy with or without minoxidil, ketoconazole, non-abative radio frequency, natural products, finasteride and cortexolone 17 alpha propionate. The post evaluates the efficacy and safety of these treatments in various studies.

community Should I dedicate my university studies to solving hair loss?

in Research/Science 373 upvotes 1 year ago

A 20 year old male who is balding and considering switching to a biology/chemistry program in order to find a low-cost, accessible solution for hair loss. Replies discuss the merits of this idea as well as potential treatments such as Minoxidil, finasteride, RU58841, TM5614, and ADQ.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community New study shows minoxidil tropical solution 5% can cause eyesight problems.

in Research/Science 178 upvotes 3 days ago

Minoxidil 5% topical solution may cause eyesight problems, with some users experiencing blurred vision. The discussion also mentions finasteride's potential side effects, including erectile dysfunction, with varied personal experiences.

community Why don’t people just just DUT instead of FIN?

in Finasteride/Dutasteride 48 upvotes 9 months ago

The conversation discusses the use of dutasteride (DUT) versus finasteride (FIN) for hair loss treatment, with some users preferring DUT for its effectiveness while others choose FIN due to its approval status, better long-term data, and lower risk of side effects. Users share personal experiences with both medications, including side effects and effectiveness.

community U.S Court let Merck hide secrets about Finasteride.

in Finasteride/Dutasteride 303 upvotes 1 year ago

Hair loss discussion involving finasteride's side effects and effectiveness. Users shared mixed experiences, with some reporting side effects and others seeing positive results.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

in Research/Science 63 upvotes 1 year ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community NW 2 -> NW 1,5 15Mg oral Minoxidil (💀) + Dut 0,5mg 12 Months

in Progress Pictures 77 upvotes 1 year ago

The user, Albertgejmr, is happy with their progress in treating hair loss using 15mg oral minoxidil and 0.5mg Dutasteride. Some users express concern about the high dosage and potential side effects.

community Be careful when switching from Finasteride to Dutasteride because for more efficacy.

in Finasteride/Dutasteride 13 upvotes 1 month ago

Switching from finasteride to dutasteride may be more effective for hair regrowth due to dutasteride's stronger enzyme inhibition, but combining both drugs could enhance results. Some users report better outcomes with dutasteride, while others recommend a gradual transition to prevent potential hair loss.

community Who here has maintained with finasteride for decades?

in Finasteride/Dutasteride 133 upvotes 11 months ago

People have been using finasteride for 10 to 20+ years to maintain their hairline, with many reporting success and no significant side effects. Some users have combined finasteride with minoxidil for better results, and a few have switched to dutasteride or added hair transplants when finasteride was less effective.

community Does anyone here use everything except Fin

in Minoxidil 23 upvotes 1 year ago

The conversation is about hair loss treatments, specifically Minoxidil (Min) and Finasteride (Fin). The original poster is considering using Min and other treatments but is hesitant about Fin, while the responses vary, with some advocating for early use of Fin and others warning about potential side effects.

community Is 2-deoxy-D-ribose (2dDR) good for human hair?

in Research/Science 9 upvotes 3 months ago

Topical 2-deoxy-D-ribose (2dDR) regrows hair in mice almost as well as 2% Minoxidil. However, 2dDR may contribute to oxidative stress and hair loss due to the formation of advanced glycation end products (AGEs).

community This is what some balding dudes are like

in Satire 1042 upvotes 3 weeks ago

Some people avoid finasteride due to side effects but engage in unhealthy habits. Minoxidil and finasteride are common hair loss treatments, with varied side effect experiences.

community [M31] 2+ years progress on Oral Dutasteride and Sublingual Minoxidil

in Progress Pictures 67 upvotes 5 months ago

A user shared their 2+ years progress on Oral Dutasteride and Sublingual Minoxidil for hair loss. Another user asked about the form of Minoxidil used sublingually.

community Finasteride vs Dutasteride: The Science

in Research/Science 168 upvotes 10 months ago

The conversation compares Finasteride and Dutasteride for hair loss treatment, discussing their effectiveness and side effects. Users share personal results and consider combining treatments like Dutasteride with RU58841.

community 2 years later I managed to gain some ground (Hyperresponder)

in Progress Pictures 43 upvotes 1 year ago

The user regained most of their hair using Minoxidil, Finasteride, and Dermarolling. They found Dermarolling particularly effective, as it promotes growth factors and improves hair thickness.

community Dermatologist didn’t want to write for Dutasteride and oral minox, instead gave me script for this 12.5% minox with tretinoin,azelaic acid, and topical finasteride. It’s 55$ a month, is it worth it?

in Finasteride/Dutasteride 6 upvotes 1 year ago

The conversation discusses a prescribed hair loss treatment combining 12.5% minoxidil with tretinoin, azelaic acid, and topical finasteride, costing $55 a month. One user criticizes the packaging for degrading tretinoin, another suggests it's an overpriced option and recommends topical dutasteride as an alternative due to its higher molecular weight and lower systemic absorption.

community Stop Using Salicylic acid on your face if using minoxidil for beard growth

in Product 20 upvotes 5 months ago

Salicylic acid can reduce the effectiveness of minoxidil for beard growth. Users discuss avoiding salicylic acid when using minoxidil.

community A hill on which I will die: The DHT itch absolutely exists

in Research/Science 209 upvotes 6 months ago

The DHT itch is linked to hair loss and persists despite finasteride use; switching to dutasteride helped alleviate the itch and promoted regrowth. Some users suggest seborrheic dermatitis as a cause and recommend treatments like medicated shampoos, vitamin D, and minoxidil.

community [Research] RU-58841/Pyrilutamide and impacts on male fertility

in Research/Science 6 upvotes 1 year ago

The drugs RU-58841, Pyrilutamide (KX-826), Apalutamide, Enzalutamide, and Darolutamide, which are nonsteroidal antiandrogens (NSAA), potentially impacting male fertility. Pyrilutamide, similar to Enzalutamide, may have reversible effects on fertility.

community Oral Minoxidil and Grapefruit Juice

in Research/Science 96 upvotes 1 year ago

The conversation is about the potential dangers of taking oral minoxidil and grapefruit juice together. Some users express concern about dangerous drug interactions, while others argue that grapefruit juice may inhibit the metabolism of finasteride. The conclusion is that grapefruit juice may make finasteride less effective, but it won't affect minoxidil.

community Optimal topical (leave in, not shampoo) caffeine concentration. Contradictions across studies.

in Research/Science 13 upvotes 1 year ago

One study suggests a 0.2% caffeine concentration is nearly as effective as 5% minoxidil for hair loss, while other findings indicate that concentrations between 0.001% and 0.005% are more effective, with 0.001% being the most effective. There is no clear consensus on the optimal caffeine concentration for hair loss treatment.

community My dermatologist uses oral minox and dutasteride

in Minoxidil 65 upvotes 2 years ago

Treatments for hair loss and the potential side effects. The user discussed their doctor's advice to take 1.25 mg oral minoxidil and .5 mg dutasteride daily, with a warning that those with heart conditions should not take oral minoxidil. Other users shared their experiences, including taking finasteride and noting the possible overkill of the dosage prescribed by Jirons1's dermatologist.

community Update: A New Therapeutic Channel - Hair Follicle Glucose Metabolism

in Research/Science 11 upvotes 2 years ago

Hair loss can be treated by correcting glucose metabolism in hair follicles and using equol as a safer DHT blocker. Production of these treatments is starting soon, and a Discord channel is available for more information.

community (UPDATE) 9 month progress on Minoxidil 5%(switched to 10% last 3months) and Finasteride 1mg per day, everyday.

in Progress Pictures 138 upvotes 2 years ago

User shared 9-month progress using Minoxidil 5% (switched to 10% last 3 months) and Finasteride 1mg daily for hair growth. Experienced improvement in hair volume, but crown still not fully filled; considering transplant if no further progress.

community About to add topical melatonin to my 5% minoxidil solution. What's would be the right concentration?

in Research/Science 13 upvotes 3 years ago

The user added melatonin to their 5% minoxidil solution for hair growth, using a concentration of 0.0033%, which equates to roughly 2mg for a 60ml bottle. They later reported no significant difference and planned to continue the treatment for a few more months before potentially stopping to observe any changes in shedding.

community Shampoo and conditioner to help get rid of dandruff? What about treatments?

in Product 7 upvotes 3 years ago

The conversation is about finding effective shampoos and conditioners for dandruff, excluding ketoconazole. The user mentions trying Paul Mitchell Tea Tree shampoo and Purology, and seeks at-home treatment recommendations.

community KX-826: Long-Term Safety Results are out!

in Research/Science 155 upvotes 1 month ago

KX-826 initially improves hair growth but declines after 24 weeks, with mild itching as a side effect. Combining it with minoxidil and finasteride may improve results, but long-term effectiveness is uncertain.

community Science backed answer only from what you have learnt .

in Chat 6 upvotes 1 month ago

Alcohol-based minoxidil absorbs better but can cause irritation; non-alcohol-based is gentler. Topical dutasteride shows promise but needs more research; low-dose oral minoxidil (0.25 mg/day) is effective with fewer side effects. Ingredients like Procapil, Redensyl, caffeine, and Anagain in shampoos have limited evidence; ketoconazole shampoo can help when used 2-3 times a week with other treatments.