A dental technician claims malocclusion causes pattern hairloss due to poor scalp circulation. Users debate this, noting treatments like finasteride, minoxidil, and microneedling focus on DHT and blood flow.
The conversation is about the effects of steroids on hairloss. Some users believe that steroids can cause hairloss, while others argue that it depends on individual sensitivity to DHT. There is also discussion about the appearance of balding individuals who use steroids.
The post discusses the side effects of various drugs causing excess hair growth, questioning why only minoxidil is used in the hairloss industry. The conversation includes users sharing their experiences and concerns about potential side effects of these drugs, with some preferring baldness over potential health risks.
A user who shared progress pictures of their scalp using a microscope camera, demonstrating the difference between healthy and miniaturized hair. Various explanations for the cause of this were discussed, such as DHT build-up in scalp sebum causing an autoimmune response leading to inflammation and eventual hairloss, with some suggesting a do-it-yourself treatment involving adding ascorbic acid powder to shampoo.
Hairloss treatments, specifically 5AR inhibitors, can impact neurosteroids and sexual health. The effects of topical fin/dut on tissue-specific DHT levels are unclear.
The conversation discusses hairloss treatments, focusing on the use of topical minoxidil, microneedling, finasteride, and dutasteride, while debating the role of testosterone and DHT in hairloss. It also touches on the potential liver health impacts of these treatments and the genetic sensitivity of hair follicles to androgens.
The user is treating hairloss with a regimen including Dutasteride, oral and topical Minoxidil, microneedling, and various supplements for overall health. They are considering adding tretinoin, stemoxydine/RU, DIM, Boron, and Fadogia Agretis to their routine.
Dutasteride doses matter for hairloss treatment and are more effective than finasteride. RU58841 is suggested for better gains, but side effect profiles should be considered.
Scalp tension potentially affecting hairloss, and potential treatments for male pattern baldness such as Minoxidil, Finasteride and RU58841. Evidence from a study was discussed which suggests that the cause of MPB lies within the follicle itself and is not dependent on its surrounding environment.
User "missbloombastic" has been experiencing hairloss since 2016 and tried min, fin, multivitamins, and spiro with mixed results. Another user shares their struggle with hairloss and its impact on self-esteem, while a third user suggests checking blood tests and confirming the cause of hairloss.
Oral minoxidil has gained popularity as a hairloss treatment, with more online discussions and research showing it's safe in low doses. A viral New York Times article also contributed to its increased acceptance.
A 25-year-old man with hairloss from bleach damage is using oral minoxidil and considering adding Dutasteride for better regrowth and prevention. He seeks advice on Dutasteride's effectiveness and potential benefits over finasteride, and is also curious about RU58841.
The conversation discusses whether to use finasteride for hairloss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.
Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hairloss by blocking DHT and promoting hair growth.
The conversation discusses the effectiveness of finasteride and dutasteride in treating hairloss, emphasizing that significant results often take 12-18 months or more. Dutasteride is generally considered superior, with similar or fewer side effects than finasteride, but patience is required for noticeable improvement.
A 21-year-old MTF individual is experiencing rapid hair thinning and is currently on estradiol valerate. They are inquiring about the effectiveness of spironolactone for hairloss, despite being aware of its serious side effects.
Switching from finasteride to dutasteride may be more effective for hair regrowth due to dutasteride's stronger enzyme inhibition, but combining both drugs could enhance results. Some users report better outcomes with dutasteride, while others recommend a gradual transition to prevent potential hairloss.
Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hairloss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.
Topical finasteride is almost as effective as oral finasteride with fewer side effects. Users are considering between oral and topical finasteride for hairloss treatment.
The conversation is about the debate over the existence of Post-Finasteride Syndrome (PFS) and its symptoms, with some users skeptical about PFS and others discussing side effects like erectile dysfunction and gynecomastia from hairloss treatments like finasteride. Specific treatments mentioned include finasteride, viagra, and a joke about using a popsicle stick for erectile support.
The user started using finasteride, minoxidil, and biotin for male pattern baldness (MPB) and is experiencing rapid thinning. They are questioning if low blood flow to the head could be contributing to their hairloss.
An 18-year-old male's successful hair regrowth after three months of using finasteride 1mg daily. He reported no side effects and other users expressed admiration and curiosity about his results.
The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.
A Dutasteride Simulator predicts serum dutasteride, serum DHT, and scalp DHT levels using models from research papers. It simulates various dosing schedules to determine steady-state effects and visualizes outcomes, including hair growth-related scalp DHT suppression.
A dutasteride simulator predicts that daily 0.5 mg dosing results in higher DHT suppression compared to less frequent dosing. Twice-weekly dutasteride may be as effective as finasteride 5 mg, providing a balance between efficacy and ease of use.
Minoxidil 5% topical solution may cause eyesight problems, with some users experiencing blurred vision. The discussion also mentions finasteride's potential side effects, including erectile dysfunction, with varied personal experiences.
The emotional impact of hairloss and the risks associated with common treatments such as finasteride, dutasteride, minoxidil, RU58841, and Fluridil. People discussed their personal experiences with these treatments, including potential side effects and lowered fertility. Hair transplants were also mentioned as a possible solution.
User experienced hair thinning after losing 100 lbs and started Dutasteride treatment. They faced side effects like fatigue, brain fog, and insomnia but no erectile dysfunction.
Hairloss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.