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      community [Nov 2019] The peptide AC 2 isolated from Bacillus-treated Trapa japonica fruit extract rescues DHT (dihydrotestosterone)-treated human dermal papilla cells and mediates mTORC1 signaling for autophagy and apoptosis suppression

       23 upvotes 6 years ago
      A peptide from Japanese water chestnut fruit may help with hair loss by suppressing DHT's effect on hair follicle cell death, potentially serving as a finasteride alternative. The treatment's effectiveness and safety in humans remain uncertain.

      community My Hair Loss Journey: How I'm Fighting to Get My Hair Back in 2023

       5 upvotes 3 years ago
      A 27-year-old man is fighting hair loss using oral finasteride, oral and topical minoxidil, nizoral shampoo, microneedling, argan oil with rosemary extract, and plans to add RU58841 and The Ordinary hair peptide serum. He seeks advice on combining these treatments and will document his progress.

      community IGF-1 and Peptides? Miracle molecule waiting to be found

       10 upvotes 1 year ago
      The conversation discusses potential hair loss treatments focusing on stimulating IGF-1 at the follicle level using growth-factor cocktails and engineered peptides, such as Acetyl Tetrapeptide-3, Copper Tripeptide-1, Oligopeptide-20, Thymosin-β4, and Palmitoyl Tetrapeptide-7. It suggests that device-assisted delivery methods like microneedling may enhance effectiveness.

      community Additional supplements / peptides to maximize finasteride benefit

      in Research/Science  3 upvotes 3 months ago
      The user is using finasteride, HGH, GHK-CU, BPC-157, KPV, biotin/collagen/keratin vitamins, ketoconazole shampoo, and low-dose naltrexone to address hair loss, avoiding minoxidil due to past shedding experiences. Adenosine is discussed as a potential alternative to minoxidil, though it is noted to be expensive and hard to find.

      community Has anyone tried those aliexp product ?

      in Product 6 months ago
      The conversation is about exploring additional hair loss treatments, with suggestions including topical melatonin, caffeine-based shampoos, redensyl, copper-peptides, pumpkin seed oil, saw palmetto, ketoconazole shampoo, and fluridil. Caution is advised against using products from AliExpress and Temu due to potential safety concerns.

      community Has anyone tried KeraXL before?

       1 upvotes 3 years ago
      A user discussed using KeraXL serum for hair loss, which contains Biochanin-A from Red clover extract and Acetyl Tetrapeptide-3. They sought feedback on its safety and effectiveness.

      community Insane hairline regrowth with natural supps and minox

      in Update  103 upvotes 6 months ago
      A 23-year-old achieved significant hairline regrowth using minoxidil, saw palmetto, collagen peptides, biotin, omega-3, iron, ketoconazole shampoo, and scalp care techniques, without finasteride or dutasteride. The user attributes success to this combination but is unsure which element is most effective.

      community Can I expect regrowth on a low dose of fin?

       19 upvotes 4 years ago
      A user's experience with hair loss and their consideration of using finasteride, minoxidil, RU58841, stemoxydine, fluridil, and peptide serum with redensyl as treatment options.

      community Going to try the theory posted here for the next 3-6 months

       188 upvotes 5 years ago
      User xEternex tries hair regrowth with daily broccoli sprouts, apple extract containing procyanidin b2, and microneedling. Others discuss potential issues with the experiment and share their experiences with vegetable consumption and hair growth.

      community What happened to that guy who’s been drinking topical minoxidil?!

      in Chat  217 upvotes 1 year ago
      A user tried various hair growth treatments, including drinking topical minoxidil, using oral minoxidil and finasteride, and applying GHK-Cu, growth hormone peptides, and liposomal sulforaphane. They experienced thicker hair, while others discussed the risks and benefits of these methods.

      community Nice product I discovered, thought I would share.

      in Treatment  456 upvotes 1 year ago
      A product that makes hair look thicker and healthier without promoting regrowth. Discussions include treatments like minoxidil, finasteride, red light therapy, and a serum with caffeine and peptides, with mixed effectiveness opinions.

      community Is this regrowth? My doctor took these photos and said I looked better.

      in Satire  142 upvotes 1 year ago
      The conversation humorously discusses an extensive and exaggerated hair loss treatment regimen, including finasteride, dutasteride, minoxidil, pyrilutamide, RU58841, and various other therapies. Despite the numerous treatments, the effectiveness is questioned, and the user humorously considers adding more minoxidil.

      community Looking for evidence-based additions to a 1% topical finasteride formulation

       1 upvotes 3 months ago
      The conversation discusses enhancing a 1% topical finasteride solution for hair retention and regrowth with additional ingredients like melatonin, caffeine, and adenosine, while considering stability and efficacy. Concerns are raised about the stability of topical finasteride, with suggestions to use oral finasteride or obtain fresh formulations from a trusted pharmacy.

      community Suggestions on Making DIY Topical Finastride at HOME.

       2 upvotes 4 months ago
      The conversation discusses making DIY topical finasteride using a hair tonic with various ingredients and suggests alternatives like Jatamansi powder, Sandalore, and products like Bare Anatomy Expert Advanced Hair Growth Serum and RevivHair Max Hair Stimulating Serum. It also mentions using topical dutasteride and minoxidil for hair growth.

      community 2026 Hairloss Nuclear Stack Update

       83 upvotes 6 months ago
      A user shared an extensive hair loss treatment regimen including dutasteride, minoxidil, tadalafil, RU58841, microneedling, and various topical and oral supplements. Responses varied, with some suggesting the regimen is excessive and others offering additional advice or expressing skepticism about its practicality and effectiveness.

      community Grow Gorgeous Intense Hair Density Serum, 2.02 fl oz, 2-pack from Costco

      1 year ago
      The user is considering using "Grow Gorgeous Intense Hair Density Serum" alongside Minoxidil and is currently taking Finasteride. Some users doubt the serum's effectiveness, while others suggest it may help with hair strength and thickness, but opinions are mixed.

      community Topical Finasteride 0.1% and Minoxidil 5% in a Anti Hairloss lotion

       1 upvotes 2 years ago
      A user is using a custom hair loss lotion containing 0.1% topical finasteride and 5% minoxidil, expressing concerns about potential systemic absorption and dosage. They are considering adjusting their regimen and seeking advice on whether to reduce finasteride concentration or change application frequency.

      community Topical solution recommendation

      in Treatment  2 upvotes 1 year ago
      The user is using finasteride 1mg every other day and seeks a topical solution excluding minoxidil. They are considering various combinations of ingredients like finasteride, dutasteride, and tofacitinib, with options for nourishing oils and other additives.

      community Topical solution recommendation

      in Product  1 upvotes 1 year ago
      The user is using finasteride 1mg every other day and seeks a topical solution to complement it, excluding minoxidil. They are considering various combinations of ingredients like finasteride, dutasteride, and tofacitinib, with options for nourishing oils and other additives.

      community Apparently you can try PP405 right now!?

       30 upvotes 1 year ago
      PP405 is likely a scam, with concerns about its legitimacy and safety, as it may cause unintended tissue growth. Users suggest sticking to known treatments like finasteride and minoxidil.

      community Why is no one talking about redensyl?

       57 upvotes 6 years ago
      Exploring the effectiveness of redensyl, a hair loss treatment, compared to minoxidil and finasteride. People shared experiences using redensyl and products containing it, such as The Ordinary Hair Serum.

      community Melatonin emerging as new treatment for androgenic alopecia?

      in Update  35 upvotes 1 year ago
      Melatonin is being considered as a potential treatment for androgenic alopecia, with some users discussing its effects and combining it with other treatments like minoxidil and finasteride. Concerns about melatonin's impact on hormones and side effects from other treatments like ketoconazole were also discussed.

      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

       737 upvotes 3 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

      community Here’s the rundown on scalp serums from a former cosmetic chemist

       34 upvotes 7 months ago
      Most scalp serums are ineffective for hair loss, with Nécessaire’s “The Scalp Serum” being the only one showing noticeable results, though it's not worth the cost. For androgenetic alopecia, clinical treatments like minoxidil and finasteride are necessary, while caffeine and capixyl may offer some benefits.