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      community Why is dutasteride's volume of distribution so much bigger than finasteride? Is it more lipophilic and crosses barriers better?

       23 upvotes 1 year ago
      Dutasteride has a larger volume of distribution than finasteride due to its lipophilic nature, allowing it to concentrate in hydrophobic areas and making it difficult to excrete. A user experiencing hair loss has been using oral finasteride for 10 months with minimal regrowth and is considering switching to dutasteride or adding oral minoxidil.

      community Dermastamping — do you use hyaluronic acid as lubricant?

       3 upvotes 1 year ago
      The conversation discusses using high molecular weight hyaluronic acid after microneedling to form a protective barrier, though it's considered expensive and offers marginal improvement. Users share experiences with different microneedling tools like derma rollers, dermastamps, and Dr. Pen, with some opting not to use any products on the scalp.

      community Opinions on best microneedling protocol? Some thoughts...

       11 upvotes 3 years ago
      Microneedling can enhance hair growth by improving minoxidil absorption and stimulating blood flow. Users discuss optimal needle depths, with some favoring shallow frequent needling for better absorption and others preferring deeper needling for stem cell activation.

      community Does onion juice actually stop hair fall, or is it just hype?

      in Treatment 1 year ago
      Onion juice may temporarily improve hair health by boosting blood circulation and providing antibacterial benefits, but it is ineffective against genetic or hormonal hair loss. Proven treatments like minoxidil and finasteride are recommended for more reliable results.

      community GHK-Cu peptide injections - what is your experience?

       13 upvotes 6 months ago
      GHK-Cu peptide injections are discussed for hair growth, but users report mixed results and suggest focusing on DHT management first. Some users combine GHK-Cu with treatments like Minoxidil and Dutasteride, but emphasize its benefits for skin rather than hair.

      community When will FAK Inhibitors / Standford Hydrogel be on the market for hair transplants?

       9 upvotes 8 months ago
      The conversation discusses the delay in bringing FAK inhibitors and Stanford's hydrogel to market for hair transplants, with a preference for FAK inhibitors over Verteporfin due to their superior potential in preventing scarring. The user expresses frustration over the slow progress and hopes for faster development by companies like FAKnostics.

      community New warning by FDA on topical finasteride

      in Research/Science  194 upvotes 1 year ago
      The FDA warned that topical finasteride can cause serious side effects like sexual dysfunction and brain fog, similar to oral finasteride. Compounded topical formulations pose additional risks due to lack of regulation.

      community [EU] Neofollics lotion, anyone has experience?

       5 upvotes 1 year ago
      Neofollics lotion is discussed as a hair loss treatment, but users report it is ineffective and not supported by strong evidence. Users suggest sticking to FDA-approved treatments like Minoxidil and Finasteride.

      community Dutasteride Mesotherapy in America

       7 upvotes 3 years ago
      The conversation is about finding providers for Dutasteride Mesotherapy in the US, which is more common in Europe. The user is asking if any mesotherapy/PRP clinic could offer it if they provide the Dutasteride.

      community Can males use topical spironolactone?

       1 upvotes 4 months ago
      Topical spironolactone is considered safe for males but is not very effective for hair loss. Some users suggest trying it since it's already purchased, while others recommend alternatives like clascoterone.

      community We made the NY Times: Finasteride for Male Baldness is Rewriting the Rules of Male Beauty

      in Finasteride/Dutasteride  242 upvotes 5 months ago
      Finasteride is being discussed as a significant treatment for male baldness, with some users sharing positive experiences and increased confidence, while others express concerns about potential side effects like loss of libido and erectile dysfunction. The conversation highlights differing opinions on the drug's impact and the broader societal implications of changing beauty standards.

      community What actually helped me reduce my hair fall

      in Update  36 upvotes 5 months ago
      The conversation discusses reducing hair fall by addressing dandruff with anti-dandruff shampoo, regular oiling, and stress management through meditation and yoga. Other users mention using ketoconazole, vitamin D, and finasteride, with some experiencing side effects.

      community How Dangerous is Oral Min Really?

      in Minoxidil  26 upvotes 1 year ago
      Oral minoxidil is generally effective for hair loss but may cause side effects like heart palpitations and facial puffiness. Users highlight the importance of monitoring blood pressure due to potential cardiovascular risks.

      community 20 months Finasteride, Minoxidil and Microneedling.

       1273 upvotes 1 year ago
      The conversation discusses impressive hair regrowth results using finasteride, minoxidil, and microneedling over 20 months. Some users suspect a hair transplant or hair system, while others inquire about specific product details and side effects.

      community We need more people trying 2.5 mg dutasteride

      in Finasteride/Dutasteride  7 upvotes 1 year ago
      Increasing the dutasteride dose to 2.5 mg may significantly reduce DHT and promote hair regrowth, with similar side effects to lower doses. Some users combine dutasteride with minoxidil and finasteride for better results, but there are concerns about long-term effectiveness and availability.

      community Is the Ru58841 hype justified?

      in Treatment  18 upvotes 1 year ago
      RU58841 is debated for hair regrowth, with some users reporting no benefits and potential side effects, while others claim success when combined with dutasteride. Many suggest safer, well-researched treatments like finasteride and minoxidil for hair loss management.

      community Red Light Therapy: my experience

       14 upvotes 2 years ago
      A user shared their positive experience with the Omnilux Red Light mask for skin and potential hair benefits, while also using Minoxidil, Dutasteride, and RU58841. They recommend the mask for those interested in skincare and red light therapy, despite being unsure of its effectiveness for hair growth.

      community If RU58841 is such an effective anti androgen

      in Research/Science  46 upvotes 2 years ago
      RU58841 is discussed as a topical anti-androgen for hair loss, but its effectiveness and safety are not well-documented, leading to mixed opinions and experiences among users. Some combine it with finasteride, but concerns about side effects and lack of FDA approval limit its popularity.

      community Tretinoin Efficacy Alone for Hair Regrowth + DHT blocker

      in Minoxidil  5 upvotes 2 years ago
      Tretinoin's effectiveness for hair regrowth alone is questioned, with interest in its use with oral minoxidil. The discussion also considers whether finasteride or dutasteride is the better DHT blocker and if switching to dutasteride is advisable for those without side effects from finasteride.

      community Trivitamin Oil + derma rolling?

       2 upvotes 3 years ago
      The conversation is about using a trivitamin oil mix (Vitamin E, D3, A, Argan Oil, Sunflower Oil) for hair thinning and whether it is safe to apply it after derma rolling. It is advised to wait 12-24 hours after derma rolling before applying any products to avoid infections or allergic reactions.

      community Homemade topical fin vs. pharmacy made topical fin

       5 upvotes 4 years ago
      A user is considering making their own topical finasteride from crushed Propecia tablets and asks if there would be any difference compared to pharmacy-made versions or products like Essegen-F. They note that making drugs at home is generally not recommended.

      community UK Dutasteride Sources and advice

       7 upvotes 15 hours ago
      The conversation discusses obtaining dutasteride in the UK for hair loss, with users recommending Oxford Online Pharmacy and Voy as sources. Some users mention combining dutasteride with minoxidil, while others discuss the effectiveness of topical versus oral options.

      community Indian friends - which generic oral minoxidil brands would you recommend?

      in Minoxidil  14 upvotes 1 month ago
      The conversation is about recommendations for generic oral minoxidil brands from India, with users suggesting brands like Dr. Reddy's Mintop, Intas Lonitab, and Asher Pharmaceuticals' Minoxihead. Users also discuss other treatments like finasteride and dutasteride, with some expressing concerns about brand reputation and supplier reliability on IndiaMart.