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      community Finasteride won’t make all your problems go away

      in Finasteride/Dutasteride  323 upvotes 9 months ago
      A user shared that while finasteride improved their hair, it didn't solve all their insecurities, suggesting that self-acceptance is key. Others in the conversation expressed varying opinions, with some feeling that finasteride significantly boosted their confidence and quality of life, while others acknowledged it as a solution to hair loss but not a cure-all for other personal issues.

      community Trestolone (MENT) as a nuclear treatment

      in Treatment  99 upvotes 2 years ago
      Experimenting with trestolone as a treatment for hair loss in an attempt to avoid DHT-related treatments such as finasteride and dutasteride, and discussing the potential effects of its receptor selectivity on the androgen receptors in the scalp.

      community Watching my younger brother bald hurts so much.

      in Treatment  265 upvotes 1 month ago
      A 19-year-old is distressed about his 17-year-old autistic brother's hair loss, projecting his own insecurities despite being on finasteride and dutasteride. Replies suggest the brother might not care about balding, and the poster should address his own issues.

      community If RU58841 is such an effective anti androgen

      in Research/Science  46 upvotes 8 months ago
      RU58841 is discussed as a topical anti-androgen for hair loss, but its effectiveness and safety are not well-documented, leading to mixed opinions and experiences among users. Some combine it with finasteride, but concerns about side effects and lack of FDA approval limit its popularity.

      community Anyone else crying themselves to sleep because of the pyrilutamide fail?

      in Technology  44 upvotes 9 months ago
      The conversation is about disappointment with pyrilutamide's performance as a hair loss treatment, with some users expressing interest in other treatments like Verteporfin, GT20029, and RU58841, while others suggest sticking with established treatments like finasteride or dutasteride.

      community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

      in Research/Science  124 upvotes 10 months ago
      The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

      community 11 months on 5mg oral minoxidil

      in Progress Pictures  974 upvotes 11 months ago
      A user's 11-month progress using 5mg oral minoxidil for hair loss. The user reported significant hair regrowth, including on the beard and eyebrows, and experienced minor side effects like headaches and increased body hair.

      community Sublingual Minoxidil - Cure to Hairloss?

      in Minoxidil  583 upvotes 1 year ago
      The conversation discusses the potential benefits of sublingual minoxidil for hair loss treatment. It suggests that sublingual minoxidil, which bypasses the liver, may have fewer side effects, greater bioavailability, and could be more effective than oral minoxidil.

      community Study shows further evidence that finasteride and dutasteride take 12-18 months or more to show significant results. Do NOT give up early

      in Finasteride/Dutasteride  244 upvotes 1 year ago
      The conversation discusses the effectiveness of finasteride and dutasteride in treating hair loss, emphasizing that significant results often take 12-18 months or more. Dutasteride is generally considered superior, with similar or fewer side effects than finasteride, but patience is required for noticeable improvement.

      community Why is no one pointing out dandruff as the number 1 evidence/symptom of MPB?

      in Chat  55 upvotes 1 year ago
      The post discusses the theory that persistent dandruff in areas prone to hair loss could be a sign of hair follicles dying due to DHT, indicating balding. The responses vary, with some users noting improvements in dandruff and hair loss with treatments like Dutasteride, while others experienced hair loss without dandruff.

      community This sub is very toxic towards people who don’t blindly follow the fin mafia

      in Treatment  226 upvotes 1 year ago
      The conversation criticizes the negative attitude towards those concerned about side effects from hair loss treatments like finasteride and minoxidil, or who prefer natural remedies. Specific treatments discussed include finasteride, minoxidil, rosemary oil, and RU58841, with an agreement that finasteride and minoxidil are proven effective.

      community How insane is this oral min shed?

      in Progress Pictures  111 upvotes 1 year ago
      A user started taking 0.625mg oral minoxidil daily for hair loss, increased the dose to 1.25mg, and experienced a significant shed, losing 70% of scalp density. They cannot tolerate finasteride due to side effects but are hopeful for hair regrowth despite the shedding.

      community 10 months fin/min progress update

      in Progress Pictures  1220 upvotes 1 year ago
      A user's 10-month progress update using finasteride and minoxidil to treat hair loss, with other users offering congratulations, jokes, advice, and questions.

      community Quit Minoxidil, keep gains w/ Fin and Stemoxydine? | Self-experiment

      in Minoxidil  52 upvotes 1 year ago
      A user experimenting with quitting using Minoxidil and replacing it with Finasteride and Stemoxydine in order to keep hair loss gains, but other users warning the original poster of potential shedding. Another user suggested phasing out Minoxidil and replacing it with Finasteride and microneedling instead.

      community Rosemary out here changing lives for the better

      in Treatment  90 upvotes 3 months ago
      Rosemary oil is being used as an addition to minoxidil and finasteride for hair health, with mixed opinions on its effectiveness. Some users report positive results, while others see no benefit or experience adverse effects.

      community HMI 115 Phase 2 - Leaked pics from Discord

      in Research/Science  357 upvotes 4 months ago
      The conversation discusses HMI 115, a new hair loss treatment with promising results, showing a significant increase in hair density after two months. Some users are skeptical, while others are hopeful for its release and potential affordability.

      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  134 upvotes 5 months ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 2 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

      community 6+ months on topical Fin/Min/RU

      in Progress Pictures  134 upvotes 2 years ago
      The user has seen positive results after over six months using 0.05% topical finasteride, 5% minoxidil, 50mg/ml RU58841, weekly needling, and twice-weekly ketoconazole shampoo for hair loss. They express gratitude for the support from an online community and are open to questions about their treatment.

      community Proof that finasteride messes with neurosteroids

      in Research/Science  230 upvotes 2 months ago
      Finasteride can impact neurosteroids, potentially causing depression and other side effects in some users. Despite these concerns, many continue using it for hair loss, with some switching to topical applications to mitigate side effects.

      community Male pattern baldness, and mental health

      in Finasteride/Dutasteride  320 upvotes 7 months ago
      A 48-year-old man has been using minoxidil for 15 years and considered finasteride but stopped due to potential side effects. He is concerned about his mental health and the impact of hair loss on self-image, and he encourages support among men experiencing hair loss.

      community My 7 month oral minoxidil progress (1mg/day)

      in Progress Pictures  389 upvotes 1 year ago
      The conclusion of the conversation is that oral minoxidil has been effective in saving and restoring hair, but it may have diminishing returns as you age. It is suggested to consider using finasteride in addition to minoxidil for better results.