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GlossaryNeurodegenerative Disease

progressive loss of neuron function or structure

A Neurodegenerative Disease is a condition characterized by the progressive loss of structure or function of neurons, including their death. Common examples include Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS). These diseases often lead to cognitive decline, motor dysfunction, and other neurological impairments, significantly impacting quality of life.

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community What is the real impact of dutasteride on neurosteroids? A little review of 2 scientific datas

in Research/Science 19 upvotes 1 month ago

Dutasteride at 0.5 mg/day does not significantly alter allopregnanolone levels, but higher doses (2.5 mg/day) do. Dutasteride may also have anti-neuroinflammatory effects, but the impact on neurosteroids is still debated.

community I find it crazy how some people like this bloke have 0 DHT sensitivity. He is on grams of anabolic steroids and has a full, thick head of hair. I wish all of on here had this guys hair genes lol

in Satire 443 upvotes 1 year ago

The conversation is about hair loss and the possibility of maintaining a full head of hair while using anabolic steroids. Some users believe that having good hair genes and taking hair loss protocols can help prevent hair loss while on steroids.

community DHT and 5AR respect post, it's importance within the brain

in Research/Science 109 upvotes 5 months ago

The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

community Anybody on here from Germany who can talk to us about alfatradiol (Avicis, Avixis, Ell-Cranell Alpha and Pantostin)? Availability, public perception, etc?

in Treatment 6 upvotes 2 years ago

Hair loss treatments discussed include Minoxidil, Finasteride, and RU58841. A user asks about alfatradiol's availability, public perception, and usage in Germany.

community ghk-cu is potent 5-ar inhibitor?

in Product 12 upvotes 6 months ago

GHK-Cu is a potent inhibitor of the type 1 5-alpha reductase enzyme in hair follicles, which may reduce hair loss without the side effects associated with type 2 5-alpha reductase inhibitors. The user previously experienced side effects with 5-alpha reductase inhibitors and is considering GHK-Cu as an alternative.

community One year anti androgen update CROWN

in Finasteride/Dutasteride 341 upvotes 1 year ago

User used Finasteride, Dutasteride, and Minoxidil for one year to treat hair loss. They discussed possibly trying RU58841 or pyrilutamide in the future.