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GlossaryNeuropraxia (nerve conduction block)

temporary nerve injury disrupting signal transmission without permanent damage

Neuropraxia, also known as a temporary nerve block, is a type of nerve injury where the nerve remains intact but its ability to transmit signals is disrupted. This condition often results from compression or mild trauma and typically resolves on its own within days to months, without permanent damage.

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community Has the user in the HMI-115 trial shared his photos now since it's April?

in Update 25 upvotes 1 year ago

A user who was part of an ongoing trial for a prolactin blocker and had regrowth, but the progress photos were not shared due to negative reactions from other users. Treatments mentioned include HMI-115, Minoxidil, Finasteride, and RU58841.

community Treatment of Finasteride Induced Gynecomastia (Male breast tissue growth)

in Finasteride/Dutasteride 15 upvotes 4 years ago

Finasteride can cause gynecomastia, which may be reversible by stopping the drug and using selective estrogen receptor modulators (SERMs) like tamoxifen. Lifestyle changes such as weight loss and avoiding alcohol can also help, but surgery may be needed if the condition persists.

community Day 11- I have removed all Scabs

in Progress Pictures 240 upvotes 10 months ago

Eleven days after a hair transplant, the user has removed all scabs and plans to resume Oral Dutasteride and Oral Minoxidil. They will also start using a serum provided by the clinic and are sharing progress and clinic information privately to avoid negative comments.

community Ultimate Stack without nuking your gender (you'll go broke)

in Treatment 79 upvotes 3 weeks ago

A hair loss treatment plan includes finasteride, dutasteride, RU58841, pyrilutamide, minoxidil, and microneedling to inhibit DHT and promote hair growth. It also recommends supplements like Reishi and Lion’s Mane mushrooms, and a shampoo with ketoconazole, caffeine, and melatonin.

community DHT and 5AR respect post, it's importance within the brain

in Research/Science 111 upvotes 9 months ago

The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

community Kinda crazy you don’t realize how much minoxidil does for you until you stop and see the loss

in Minoxidil 89 upvotes 9 months ago

People shared experiences of hair loss after stopping minoxidil, despite also using finasteride. Some tried microneedling or hair transplants, but stopping minoxidil often led to significant hairline recession.

community Just had this wild thought come into my head.

in Satire 403 upvotes 9 months ago

The conversation is about the debate over the existence of Post-Finasteride Syndrome (PFS) and its symptoms, with some users skeptical about PFS and others discussing side effects like erectile dysfunction and gynecomastia from hair loss treatments like finasteride. Specific treatments mentioned include finasteride, viagra, and a joke about using a popsicle stick for erectile support.

community Impressed by the progress but think it’s time to go for the transplant?

in Progress Pictures 288 upvotes 10 months ago

The user started taking 2.5mg minoxidil tablets daily and reduced their finasteride dose to 0.5mg due to side effects. They are considering a hair transplant but are unsure if they should proceed now or wait after seeing the effects of the reduced finasteride dosage.

community 18->24 six years of Fin and Minox…. I guess we can’t all be winners 😭

in Progress Pictures 572 upvotes 2 years ago

A user named "EgyptStar81" who has been dealing with hair loss since age 15 due to genetics, chemotherapy and finasteride/minoxidil treatment. Possible solutions such as dutasteride, oral minoxidil, hair transplants and extensions were suggested.

community 18 Months Minoxidil 5% Before & After

in Progress Pictures 512 upvotes 2 months ago

The user used Minoxidil 5% for 18 months, seeing improved hair density but no change in the crown area. They are cautious about using Finasteride again due to past gynecomastia.

community Another clueless guy fearmongering and spreading misinformation

in Chat 251 upvotes 10 months ago

The conversation discusses hair loss treatments, with some users advocating for finasteride and minoxidil, while others express concerns about potential side effects of finasteride. A social media influencer is criticized for promoting scalp massages and minoxidil over finasteride, which some believe is misinformation.

community My Pyrilutamide Experience Photos

in Update 602 upvotes 2 years ago

A user's experience with Pyrilutamide, a topical treatment for hair loss that they used in combination with other treatments such as Minoxidil and Finasteride. The user experienced impressive results in a short amount of time.

community My fin experience over 13+ years

in Chat 150 upvotes 2 years ago

The user's experience and success with taking finasteride to treat hair loss, which is confirmed by other users who have taken it without side effects. The user also advises that consulting a doctor before starting any kind of treatment for hair loss is important, as opposed to relying on self-made remedies available online.

community The theory that explains everything. Please help me make this big!

in Research/Science 2447 upvotes 3 years ago

The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.

community Why I believe PFS is not a "real" condition (and what I believe it is instead)

in Finasteride/Dutasteride 14 upvotes 2 years ago

The post argues that Post-Finasteride Syndrome (PFS) is likely not real and suggests symptoms may be due to mental health issues or the nocebo effect. The conversation includes personal experiences with finasteride, highlighting both positive and negative effects, and emphasizes consulting doctors and using reliable sources for medication.

community Possible explanation of why Dutasteride seems to be worse for some people’s hair.

in Treatment 47 upvotes 1 year ago

The conclusion of the conversation is that some individuals may experience a condition called reactionary hypergonadism when taking dutasteride for hair loss. This condition can lead to an increase in testosterone levels, which may worsen hair loss instead of improving it.

community How effective is spironolactone?

in Transgender 6 upvotes 2 years ago

A 21-year-old MTF individual is experiencing rapid hair thinning and is currently on estradiol valerate. They are inquiring about the effectiveness of spironolactone for hair loss, despite being aware of its serious side effects.

community Minoxidil Eye Bags and Dark Circles

in Minoxidil 23 upvotes 1 year ago

Minoxidil users report dark circles and eye bags. Solutions include water pills, caffeine serum, retinol, and collagen peptides.

community We need to talk about DHT itch

in Treatment 2 years ago

DHT Itch and its link to balding, with various treatments such as finasteride being discussed. Members shared their experiences of scalp itch before and after taking 5AR inhibitors, and potential underlying causes such as seborrheic dermatitis were discussed.

community My Theory Regarding a Cause and Cure for Androgenetic Alopecia

in Treatment 97 upvotes 4 years ago

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

community Safety of RU-58841: I talked to the Pharma Company that researched it, Human Clinical Trials, and Potential Reasons for Discontinuation

in Research/Science 144 upvotes 1 year ago

The safety and effectiveness of RU-58841 as a hair loss treatment, with some users reporting side effects like chest pains, while others had positive results. The original research on RU-58841 was likely stopped due to financial issues, not safety concerns.

community Please stop looking for a natural way to stop your hairloss

in Chat 247 upvotes 2 years ago

There is no natural way to stop hair loss; pharmaceuticals like minoxidil, finasteride, and RU58841 are the only effective treatments. Some users report success with minoxidil and microneedling, while others discuss the side effects of finasteride.

community My personal experience/observations fighting AGA seriously for 5 years

in Treatment 43 upvotes 2 weeks ago

Minoxidil with alcohol and propylene glycol was more effective than non-alcohol versions, and RU58841 worked best in a non-water-based solution. Oral finasteride showed better results than topical, despite side effects; microneedling and tretinoin worsened hair loss, and PRP was only helpful when younger.

community Starting Pyrilutamide tomorrow. Will keep everyone updated

in Research/Science 178 upvotes 2 years ago

The user healthydudenextdoor starting a new topical anti-androgen hair loss treatment, Pyrilutamide, and discussing their current regimen of finasteride and minoxidil.

community This is my 3 year progress. My routine is Finasteride 1 mg a day, Topical Minoxidil 5% twice a day, and Derma Rolling three times a week.

in Progress Pictures 1 year ago

A 3 year progress of using Finasteride, Minoxidil, and Derma Rolling for hair loss; it has resulted in considerable improvement.

community Minoxidil Finasteride heart problems

in Update 97 upvotes 7 months ago

A user experienced heart problems after taking 1mg finasteride and 2.5mg oral minoxidil and is considering quitting minoxidil. Others discussed their experiences with heart issues and minoxidil, with some suggesting topical minoxidil as a safer alternative.

community For those who switched from finasteride to Dutasteride !

in Chat 43 upvotes 10 months ago

People discussed switching from finasteride to dutasteride for hair loss treatment. They reported satisfaction with dutasteride, noting it was more effective than finasteride, particularly after finasteride's effects diminished, and some experienced additional benefits like cost savings and stabilized hair loss, rating dutasteride highly as a treatment.

community New potential hair loss treatment (news release)

in Treatment 186 upvotes 4 years ago

New potential hair loss treatment uses molecules from hairy moles to stimulate follicle growth. Topical solution requires less frequent application, like Botox injections a few times per year.

community Do you recommend oral minoxidil after your full experience?

in Minoxidil 9 upvotes 8 months ago

LemonyBonobo started oral minoxidil a week ago, experiencing significant shedding, and is concerned about potentially worsening their hair condition. They also use dutasteride, topical minoxidil, and dermarolling. Elyktronix, who has been on oral minoxidil for 15 months, recommends it, noting that shedding can be a positive response and that results take time.

community Scalp pain, diffuse thinning and Fin+nizoral

in Chat 7 upvotes 9 months ago

A user experiencing scalp pain and diffuse hair thinning is taking finasteride and using Nizoral shampoo. They plan to continue finasteride for 6 months and consider adding minoxidil if no improvement is seen.