KX-826/pyrilutamide is undergoing an additional one-year safety and efficacy trial in China after a six-month study. Some participants speculate on the reasons for the extended trial and discuss the potential of other treatments.
The conclusion of the conversation is that the user has experienced significant hair regrowth using a mixture of oils, including rosemary essential oil, peppermint essential oil, and carrier oils like castor oil or jojoba oil. The user also clarifies that both pictures were taken with damp hair.
The conversation is about the comparison between finasteride and dutasteride for hairlosstreatment. The conclusion is that there is more fear around finasteride due to its higher prevalence and being the first line of defense, while dutasteride is less commonly prescribed and used by those who have already tried finasteride without side effects.
The post and conversation are about a user's progress with hairlosstreatments. The user has been using oral minoxidil and finasteride for several months and recently added dutasteride. They also use Nizoral shampoo. The user is happy with the results so far.
User had a hair transplant in 2016 but stopped taking finasteride due to side effect concerns. Now considering another transplant and starting finasteride, minoxidil, and microneedling to improve hair situation.
User experienced regrowth and thicker hair after using Minoxidil, Finasteride, and Keto shampoo for about a year. They also mentioned using 5% topical Minoxidil, 1mg oral Finasteride, and vitamin D.
User tried Minoxidil and Finasteride for hairloss with no success and considers giving up. Others suggest continuing treatment, trying hair transplant, or embracing baldness.
User takes topical finasteride/minoxidil with little results, asks if microneedling helps for temple regions and if 0.5mm is enough. Replies suggest microneedling is effective and 0.5mm works, sharing personal regimens.
User started 0.5 mg dutasteride in September 2022 and oral minoxidil in February 2023. Hairloss increased initially, but improved after increasing minoxidil dosage.
Hairloss progress discussed with 4.5 months on topical fin (0.025% liposomal). User uses rosemary oil for scalp health, and others think there might be some thickening or maintenance.
User "hairplsrn" shares their hairloss journey, trying various treatments like finasteride, minoxidil, and dutasteride, but experiencing worsening hairloss. They decide to get a partial frontal hair system and continue medication, while others offer support and advice on staying on medication and focusing on overall confidence.
User harlital shared their 9-month hairloss journey using finasteride, minoxidil, and microneedling but experienced worse results. Commenters suggested patience, checking for other causes, and considering dutasteride after 12-24 months if no improvement.
User shared 1.5-year progress using 1mg finasteride, 15% minoxidil daily, and derma rolling weekly. Experienced initial shedding but achieved significant hair regrowth and improvement.
A user who had FUT surgery for 2877 grafts with Dr Jerry Wong of Hasson & Wong that resulted in low growth and an abnormally wide scar, suggesting negligence by the doctor and possibly illegal behaviour by an unqualified technician. The post sparked discussion about seeking legal action, as well as criticism of the clinic's high cost.
Exploring different treatments for hairloss, such as cosmeRNA and HMI-115 which are small interference messenger RNA that inhibits the DHT receptor and an antibody that binds to the prolactin (PRL) receptor respectively; and researching mechanism and environment of hyperresponders.
Someone's two-month progress using oral minoxidil (2.5mg ED) to treat hairloss, which has resulted in thicker eyebrows and eyelashes but no scalp changes or shedding.
The conversation discusses using finasteride or dutasteride to reduce DHT, CosmeRNA to target androgen receptors, and Minoxidil as a vasodilator for hair growth. The regimen aims to maintain hair by addressing DHT-AR ratio and continuous Minoxidil use.
The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.
The user tried Minoxidil without success, and Finasteride worked but caused sexual side effects even at a very low dose. They are seeking alternative treatments for hairloss as they cannot tolerate anti-androgens and are also in therapy for mental health.
The effectiveness of Dutasteride compared to Finasteride in treating hairloss, with evidence given such as studies and experiences, as well as discussion around whether one should switch from Finasteride to Dutasteride. There is also a discussion on post-Dutasteride syndrome.
HMI-115, a newly discovered hairlosstreatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.
The conversation discusses using homemade topical finasteride for hairloss, showing an increase in DHT levels despite treatment. The user applies 0.125mg daily, resulting in 113.4% of previous DHT levels.
Whether Finasteride can keep alive the hair gained by Minoxidil after quitting it, and why beard hairs are not as susceptible to miniaturization. It is suggested that scalp hair may be dependent on Minoxidil and that DHT could be countered with Finasteride to some extent, but there is no definitive data proving this.
Maintaining scalp hair and minimizing shedding, treatments used such as Procapil, supplements, topical caffeine, topical estrogen, and scalp massage; suggestions for anagen extenders or pharmaceuticals to help with a short anagen phase.
Low-level laser therapy (LLLT) stimulates hair growth but current devices are expensive. A proposed non-profit project aims to create affordable, 3D-printed LLLT devices and collect data on their effectiveness.
The conversation discusses the potential of a new hairlosstreatment, GT20029, which may prevent hairloss by destroying androgen receptors on the scalp. Users express hope for the treatment's success and speculate on its usage routine, effectiveness, and possible side effects.
Finasteride, a medication for hairloss that has both positive and negative effects. Users discussed their own personal experiences with the drug as well as potential side-effects of taking it, such as erectile dysfunction or gynecomastia. Suggestions were also made about starting at a lower dosage to minimize these risks.