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Discouragement regarding Pyrilutamide, a drug in development for hair loss, and the potential side effects of Finasteride. People discussed anecdotal experiences with Pyrilutamide as well as suggestions to wait out Phase 3 trials before making any conclusions.

A 25-year-old male with normal hormone levels is considering starting finasteride and minoxidil for hair loss but is concerned about high estradiol levels and potential side effects. Responses vary, with some suggesting blood tests before starting treatment and others emphasizing individual tolerance and the importance of consulting a doctor.

OP reports that after 3 months on 2.5mg dutasteride, their hair has stopped falling out and is thick again, but they are considering stopping due to potential mood and energy side effects. Other users discuss experiences with finasteride, dutasteride, and side effects, with some suggesting lower doses or alternative treatments like topical applications.

Significant hair regrowth was achieved using oral finasteride and topical minoxidil over five months, with noticeable improvements in hairline and temple areas. The user experienced minimal side effects, mainly increased eyebrow and eyelash growth, and attributes additional physical improvements to weight loss and exercise.

The post and conversation are about using bimatoprost for hair regrowth, with the user seeking a higher concentration to enhance results. The user also discusses difficulties in sourcing the powder for personal use.

The efficacy of low doses of finasteride to reduce scalp DHT, and whether studies showing a 61% reduction are reflected in actual results. Replies discussed hair growth as an unintended consequence of minoxidil and finasteride use, as well as self-selective bias, potential side effects, and that studies measure effectiveness by hair count changes rather than DHT inhibition.

The user, SnooDonuts9235, shares their positive experience with a hair transplant and using topical finasteride and minoxidil. They express concern about increased shedding and ask if it is normal. Other users compliment their results and ask about the clinic and procedure details. SnooDonuts9235 encourages others to consider a hair transplant even without taking oral finasteride and shares that the procedure was not as scary as they initially thought.

User has been using topical finasteride and minoxidil for a year, seeing regrowth only on the hairline, not the crown. They also use keto shampoo, rosemary oil, and microneedle weekly, and are considering switching to oral treatments.

A user is considering switching from finasteride to dutasteride after minimal success with finasteride, minoxidil, and other treatments. Another user reports positive results with dutasteride after switching from finasteride.

Improving diet and taking supplements like Biotin, B12, D3, iron, zinc, and protein can enhance the effectiveness of hair treatments. However, responses to treatments like Minoxidil and finasteride vary, and some users report no improvement despite a good diet.

Akinfenrawr experienced negative side effects from oral finasteride and RU58841, and is seeking alternative hair loss treatments. They discuss various options, including raloxifene, oral dutasteride, liposomal finasteride, Breezula, Pyrilutamide, SM04554, and sulforaphane, but have concerns about efficacy, availability, and cost.

The user switched from finasteride to dutasteride for hair loss and saw significant improvement in under two months. They also microneedle, take supplements including collagen and vitamin D3, use ketoconazole shampoo, and noticed accidental hair regrowth with retinol application on their face.

Using a microdose of finasteride on the scalp with minoxidil as a carrier may have positive effects with minimal side effects. The user is also considering the effects of sulforaphane or broccoli sprouts on hair loss.

The user reported minimal results for the first 7-8 months using finasteride every other day and minoxidil once a day, but recently noticed hairline improvement and increased density. They also started microneedling once a week.

User pancake9001 experienced minimal hair growth with Minoxidil for 3 years, but noticed dramatic hair loss after stopping. Replies suggest not stopping Minoxidil and considering adding an anti-androgen for better results.

A female user is experiencing minimal regrowth and miniaturized hair after 6 months of treatment with oral minoxidil, spironolactone, and topical minoxidil. She seeks advice on whether she can restore her remaining follicles.

User on Finasteride and Minoxidil saw minimal regrowth, tried micro needling with derma pen and noticed thin hair regrowth. Asks if micro needling hair gets thicker eventually.

Alfatradiol is discussed as a hair loss treatment with minimal side effects, but its effectiveness is debated, and it's not widely known or available outside Germany. Some users report side effects like gyno and ball ache, while others find it effective in stopping shedding and itching.

KX-826 shows promise for hair maintenance at higher doses with minimal side effects, despite failing Phase III trials. The user believes it is more effective than Minoxidil, Finasteride, and RU58841.

The user has been using finasteride for over four years with minimal side effects, successfully stopping hair thinning and achieving some regrowth. They shared progress photos, but some commenters requested clearer pictures of the crown to better assess the treatment's effectiveness.

A user has been on finasteride for over a year with minimal hair regrowth and is considering stopping it, despite no side effects. They are also planning a hair transplant and seeking additional hair growth treatments, while managing high testosterone and scalp issues like dandruff and oiliness.

Topical finasteride with hydroxypropyl chitosan shows significantly less serum absorption and minimal DHT reduction compared to oral finasteride. Users need the specific chitosan formulation to avoid side effects seen with regular ethanol+PG solutions.

Hair loss discussion includes topical Spironolactone's effectiveness and minimal side effects. Community members share personal experiences and opinions on its use.

Finasteride is effective for treating male pattern baldness (MPB) with minimal side effects, and topical finasteride is similarly effective. Dutasteride is also effective but less understood, and Minoxidil is less effective than Finasteride.

The conversation discusses using a low dose of topical finasteride to achieve hair benefits with minimal systemic exposure. Users share experiences and opinions on dosing, systemic buildup, and side effects of both topical and oral finasteride.

A user who decided to shave their head after trying PRP for hair loss with minimal results, and the replies which commended them on how good they looked without it.

The conversation discusses trying zinc gluconate for hair loss after biotin showed minimal effect. The user is considering switching treatments.

Caffeine intake may increase DHT levels, but its impact on hair loss is minimal compared to genetic factors. Excessive caffeine can cause health issues, and its effects on hair loss are not directly applicable to humans based on rat studies.

A user stopped hair loss after taking finasteride daily for four years, with minimal regrowth and no side effects. They believe stress initially caused their hair loss.

A user is losing hope after 5 months on finasteride, seeing more hair loss and minimal positive changes. Another user advises that shedding is normal and benefits may take up to 2 years.