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GlossaryMetformin

oral diabetes medication that lowers blood sugar levels

Metformin, also known by brand names such as Glucophage, is an oral medication commonly used to manage type 2 diabetes. It works by reducing glucose production in the liver and improving the body's sensitivity to insulin, thereby helping to control blood sugar levels. Additionally, metformin is sometimes used off-label for conditions like polycystic ovary syndrome (PCOS) due to its effects on insulin resistance.

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community Topical rapamycin, metformin, a-kg grow hair

in Research/Science 13 upvotes 4 years ago

The conversation discusses the potential of topical rapamycin, metformin, and alpha-ketoglutarate (a-KG) for hair growth, with skepticism expressed about their effectiveness based on personal experience and existing use. It also mentions AICAR, known as cardarine or GW, which is not suitable for long-term use due to cancer risks in animal studies and its similarity to metformin.

community Finasteride and Metformin together?

in Finasteride/Dutasteride 1 upvotes 1 year ago

The conversation is about whether it's safe to take Metformin for weight loss and Finasteride together, with the concern that Finasteride is not commonly used for hair loss treatment in the user's location, and their doctor is not knowledgeable about it.

community Research suggests that drugs rapamycin and metformin have hair regeneration properties

2 upvotes 6 years ago

Rapamycin and metformin may have hair regeneration properties. Specific treatments discussed include Minoxidil, finasteride, and RU58841.

community What can I use to prepare a lotion that doesn't irritate my scalp or make my hair sticky? (Want to experiment with metformin and Alpha Keto glutarate)

in Product 2 upvotes 1 year ago

The conversation is about a user who tried dissolving a metformin pill in water for hair treatment but faced issues with hair sticking together. The user is seeking advice on preparing a non-irritating, non-sticky lotion at home, possibly experimenting with metformin and Alpha Keto glutarate.

community Anti-Androgens causing hairline to recede?

in Research/Science 5 upvotes 5 months ago

Anti-androgens like Finasteride, Dutasteride, Metformin, and Topical Spironolactone cause hairline recession and increased cholesterol levels. The hairline recovers after stopping the drugs.

community Akkermansia improves testosterone-induced hair growth inhibition.

in Research/Science 3 upvotes 1 year ago

Akkermansia bacteria can improve hair growth inhibited by testosterone, and metformin may increase Akkermansia, which could help with hair loss related to aging, insulin resistance, and inflammation.

community currently active protocols, working so far

in Update 1 year ago

The conversation is about a person's hair loss treatment routine, which includes Metformin, sleep in darkness, avoiding EMF at night, Nizoral, Dermarolling, Castor oil, and Collagen. They have observed less hair shedding and increased hair volume.

community Do we have to be junkies? That's funny

in Research/Science 13 upvotes 5 months ago

The conversation discusses using finasteride, dutasteride, minoxidil, cialis, and metformin to protect hair and health. Some users caution against self-prescribing these drugs due to potential risks and complications.

community What treatment helps diffuse hair thinning from insulin resistance?

in Treatment 1 upvotes 1 year ago

The individual is experiencing hair loss due to insulin resistance (IR) and is seeking advice. They are currently using a keto diet, supplements, exercise, and plan to add metformin to their regimen.

community Wtf have we been doing for the last 30 years

in Treatment 526 upvotes 4 days ago

Hair loss treatments like finasteride, minoxidil, and dutasteride work but have side effects. A permanent cure is still not available due to the complexity of hair loss and limited investment.

community Not all generic medications are made equal. Some work great, some weaker, and some are dangerous. What Pharmaceutical makes your current/past generic Finasteride?

in Finasteride/Dutasteride 7 upvotes 3 years ago

The conversation discusses the variability in effectiveness and safety of generic finasteride from different manufacturers, with some generics potentially containing impurities. Users shared their experiences with various brands, questioning if different brands affect hair loss treatment outcomes.

community 9 month before and after, dut only

in Finasteride/Dutasteride 37 upvotes 2 months ago

The user experienced noticeable hair growth after 9 months using oral dutasteride, with full results expected in 20-24 months. They prefer oral treatments over topical minoxidil due to convenience.

community 1 Year Update - 40 y/o, Topical Min/Fin, 1.5 mm Microneedle Weekly

in Progress Pictures 122 upvotes 1 year ago

The post is a 1-year update on hair loss progress using topical minoxidil and finasteride treatments. The user has seen good progress, especially in transitioning from a Norwood 3 to a Norwood 2 hair loss pattern.

community Topical quercetin combined with finasteride for max results

in Research/Science 25 upvotes 1 year ago

Combining Finasteride with topical Quercetin, Onion/Garlic juice and Peppermint Oil to reduce Wet Prostate Weight in Rats. Luke10191 asked the user LITUATUI to update them on progress after trying this combination of treatments for hair loss.

community 8 month update. Topical fin/min, topical dut, mk677, RU, micro needling

in Progress Pictures 217 upvotes 3 years ago

User shared 8-month hair loss treatment progress using topical fin/min, topical dut, mk677, RU, and microneedling. They experienced watery semen as a side effect but saw significant improvement in hair growth.

community PP405: The Ultimate Hair Loss Drug for Complete Hair Growth

in Research/Science 198 upvotes 2 days ago

PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.

community Topical Anti-Androgen users. What are y’all using currently? And what do you believe has the best chance of being approved? Or best results?

in Technology 13 upvotes 2 months ago

RU58841 is considered effective by some users, but finasteride and minoxidil are commonly used with varying dosages to manage side effects. Users report different experiences with treatments like pyrilutamide, fluridil, and RU58841, with some seeing results and others not.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 4 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community 57% increased chance of pattern hair loss independently associated with the consumption of sugary beverages in men (p<0.001) Pt 2

in Research/Science 479 upvotes 4 months ago

Sugary beverages increase the risk of pattern hair loss in men by 57%. Treatments discussed include Minoxidil, finasteride, and RU58841.

community Started Finasteride almost three months ago and I'm upset

in Update 153 upvotes 9 months ago

A user started taking finasteride three months ago to treat hair loss and unexpectedly cleared their acne, which they had been struggling with since age 12. The conversation includes others sharing their experiences with finasteride, its effects on acne and hair loss, and mentions a related treatment, clascoterone, for acne and hair loss.

community Increasing Oral Minoxidil Dose Over Time

in Research/Science 94 upvotes 9 months ago

A user reports hair loss despite using minoxidil and plans to increase their oral minoxidil dose gradually while also taking finasteride, dermarolling weekly, and applying topical stemoxydine nightly. They shared a link suggesting that increasing minoxidil dosage can improve hair growth and thickness.

community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

in Female 53 upvotes 1 year ago

A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

community C’est terrible - at my wits end

in Female 449 upvotes 1 year ago

A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

community 137 years old and still far more hair than the average r/tressless user

in Satire 1060 upvotes 1 year ago

The post and conversation are about a user claiming to be 137 years old with a full head of hair. Specific treatments mentioned include dutasteride, RU58841, and minoxidil.

community PCOS female who posted before; saw Endo today. prescribed spironolactone and minox 5%

in Update 1 upvotes 1 year ago

PCOS female visited doctor for hair loss concerns, prescribed spironolactone and minox 5%. Doctor advised against finasteride or dutasteride, user considering self-medication with dutasteride.

community I don’t even care about my hair I just like taking drugs

in Satire 1 year ago

A user's experimentation with various hair loss treatments, including medications and topical applications; as well as their desire to experience unusual sensations through the use of drugs.

community Is dutasteride every other day better than finasteride everyday?

in Finasteride/Dutasteride 34 upvotes 1 year ago

The efficacy of taking dutasteride, a medication used to treat hair loss, every other day instead of daily. It was suggested that taking 0.5mg daily for 3 months and then switching to 3 times per week would be effective. Finasteride was also discussed as an alternative treatment option.

community I'm a 32 year old male with Norwood 3 with heavy diffuse thinning, I'm about to start my hair loss regiment. It goes as follows

in Update 22 upvotes 1 year ago

A 32-year-old male with Norwood 3 and heavy diffuse thinning is starting a hair loss treatment including RU58841, Minoxidil, finasteride, derma rolling, vitamins, and possibly MK677, while cutting out most sugars from his diet. He plans to share progress photos and updates on his test levels.

community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

in Research/Science 743 upvotes 2 years ago

A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

community One+ year 1mg Fin, Ketoconazole, and 3.75 Oral Min. I have DUPA. Switched from Topical to Oral Min.

in Progress Pictures 142 upvotes 2 years ago

A user's experience with hair loss treatments such as finasteride, ketoconazole, and oral minoxidil that have not yielded any results; other users suggest shaving the head or getting a wig, while others offer additional advice such as seeing a dermatologist, checking thyroid levels, switching to dutasteride and adding needling, and trying stemoxydine.