A user added 1% NMN to their 5% minoxidil mix for hair loss, which also includes melatonin, ginkgo, nettle root, and plans to add caffeine. They are asking if anyone has tried topical NMN for hair growth.
The conversation discusses concerns about brain fog potentially caused by finasteride use, with some users sharing personal experiences of cognitive issues and others suggesting it might be paranoia or unrelated. The original poster decides to stop using finasteride to see if their cognitive function improves.
The user cannot handle Minoxidil and is looking for an alternative to dilute topical finasteride. They are considering using Alpecin liquid as a solution.
Suvomipic, previously known as PP405, is progressing to Phase 3 trials for hair loss treatment. Its effectiveness compared to existing treatments like Minoxidil and Finasteride is still uncertain.
A 24-year-old user shared their 12-month progress using 1mg oral finasteride and 5mg oral minoxidil for hair loss, reporting significant improvement after initially starting with 2.5mg minoxidil. They experienced no side effects and noted thicker eyelashes, with results becoming noticeable around the 9th or 10th month.
The conversation discusses hair loss treatments, specifically using 1.2mg finasteride and 3mg oral minoxidil over 9 months. The user reports progress but notes a recent decrease in hair density, possibly due to shedding.
Topical sodium valproate may promote hair growth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.
A user wants to add cetirizine tablets to their minoxidil bottle and asks how many 10mg tablets to crush for a 100ml bottle. They seek advice on the correct dosage.
Pyrilitamide (KX-826) did not show significant improvement in hair count compared to placebo after 6 months. It's unclear if it can maintain hair at baseline.
P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.
A 29-year-old male reports using 1.25mg finasteride daily and applying minoxidil twice daily to the temples for hair loss, noting modest progress over 13 months. He attributes rapid hair loss onset to creatine use and is considering a hair transplant in the future.
A user is considering switching from regular 5% minoxidil foam to a compounded 5% minoxidil spray with added caffeine, melatonin, and tretinoin for easier application and potentially better results. Another user mentions that tretinoin can enhance minoxidil's effectiveness by converting it to its active form.
User tried oral and topical finasteride for hair loss but experienced headaches and concentration issues. They ask for advice on whether to continue or try other treatments like alfatradiol, fluridil, or pyrilutamide.
The user has been using a daily capsule containing 1mg finasteride and 2.5mg minoxidil for 11 months, with noticeable regrowth on the crown but minimal improvement on the hairline. They experienced no significant side effects and plan to continue the treatment long-term.
The conversation discusses hair loss treatments, specifically using Minoxidil, microneedling, and finasteride. The user is concerned about worsening hair loss and is advised to consider finasteride.
Topical melatonin shows promise for increasing hair density with minimal side effects. The user is transitioning from oral finasteride to a compounded minoxidil and finasteride solution and considering melatonin and bimatoprost as additional treatments.
Oral Minoxidil users discuss whether caffeine affects its effectiveness due to adenosine receptor blockade. Users report no significant impact on hair growth despite caffeine consumption.
The conversation is about managing allopregnanolone deficiency caused by 5-alpha-reductase inhibitors like finasteride or dutasteride. Specific treatments discussed for hair loss include Minoxidil, finasteride, and RU58841.
RU58841 and Minoxidil can cause heart-related side effects like chest pain and heart racing. Pyrilutamide is suggested as a safer alternative, though it's new and costly.
A user shared a positive experience using Minoxidil (2.5mg) and Finasteride (1mg) daily for hair loss, noting initial side effects like numbness and reduced alcohol tolerance but overall hair improvement after a year. They also used rosemary shampoo and supplements, emphasizing the importance of consulting a dermatologist and maintaining a healthy lifestyle.
The conversation discusses transitioning from topical to oral minoxidil for hair loss treatment and explores the potential use of Aminexil, despite concerns about its effectiveness compared to minoxidil. It highlights the risks and side effects of oral minoxidil, such as potential heart and liver damage, and emphasizes the importance of monitoring blood pressure.
The user reported hair recovery on the scalp after 4 months using finasteride and 5% topical minoxidil, with anxiety as a side effect. Reducing caffeine intake helped manage anxiety, which may be linked to minoxidil's effects.
The user is experiencing insomnia after starting finasteride and is seeking solutions without quitting the medication. Suggestions include trying ZMA, maintaining consistent sleep habits, and considering other sleep aids like Nytol or melatonin.
A 19-year-old male with a family history of balding is using finasteride to thicken his hair and is considering whether to add minoxidil. Users suggest continuing finasteride for several months before deciding on minoxidil.
OP experienced heart issues after taking pilocarpine, which they believe interacted negatively with oral minoxidil, leading to hair loss. They stopped pilocarpine but can no longer use oral minoxidil.
The conversation is about comparing the effectiveness of adenosine and minoxidil for treating hair loss. People are sharing their thoughts and experiences on which is better.
Switching from minoxidil foam to topical solution and considering adding caffeine, melatonin, or cetirizine. Currently using 2.5mg oral minoxidil and 1mg oral finasteride, planning to ask for 0.5mg oral dutasteride and 5mg oral minoxidil.
A user applied the 8T3 product for hair loss, targeting LPP and AGA, and plans to update on its effectiveness. The product uses a saline buffered phosphate vehicle, suitable for those intolerant to ethanolic vehicles.
Prolonged use of topical minoxidil and finasteride can lead to neuroendocrine and autonomic dysfunction, causing severe sensitivity and side effects. Recovery involves avoiding these treatments, supporting neurosteroid recovery, calming the sympathetic system, and rebuilding scalp health naturally.