Gut microbiota significantly influences androgen metabolism, impacting hair loss treatments like finasteride. Probiotics, dietary changes, and fecal microbiota transplants may help manage DHT levels and improve hair health.
Topical dutasteride 0.05% is more effective for hair growth than oral finasteride 1mg, with minimal DHT reduction. The formulation uses castor oil and MCTs for better absorption but is not widely available until 2028.
A 30-year-old MTF individual shares their hair regrowth journey using feminizing HRT, Minoxidil, and occasional dermarolling, noting significant progress but acknowledging ongoing challenges with thin hair. They express hope for continued improvement and consider a future hair transplant if necessary.
A user with medium length hair and thinning at the top is using an adenosine-based hair growth serum and seeking advice on whether to use a boar bristle or nylon bristle brush to stimulate hair growth. They are concerned about their sensitive scalp.
A promising stem cell treatment for hair loss using adipose-derived stem cell conditioned medium is discussed. Users express interest in the treatment's cost and effectiveness, noting impressive results from a 2015 study.
TDM-105795 is a potential hair growth stimulant that works differently from minoxidil and could be used alongside it for enhanced growth. It completed phase 2 trials in 2024, with a medium to high chance of release in 2026, but lacks recent updates or phase 3 trial information.
Adipose-derived stem cells with ATP improved hair regrowth in male and female mice with androgenetic alopecia. The most effective treatments were low dose stem cells with ATP for males and medium dose stem cells with non-liposomal ATP for females.
The user started using finasteride daily and ketoconazole occasionally, noticing reduced hair fall but no regrowth. Others shared mixed experiences with finasteride, some considering switching to dutasteride or adding minoxidil.
To increase hair density appearance, options include using hair fibers, volume powders, scalp micropigmentation, and a combination of sea salt and holding sprays. Tape-in extensions and clip-in fringes are also considered, but cost and maintenance are concerns.
A 22-year-old male experiencing hair thinning is considering starting finasteride but is concerned about potential side effects and hereditary factors. While waiting to access finasteride, he plans to use pumpkin seed oil, saw palmetto, biotin, and vitamins, and is advised to check blood levels before starting treatment.
Switching from powdered dutasteride to softgel significantly reduced DHT levels, suggesting softgels are more effective due to better bioavailability. Users discuss the ineffectiveness of compounded forms and emphasize the importance of proper formulation for absorption.
The user shared a 14-month progress update using a 4-in-1 topical solution containing 0.3% finasteride, 7% minoxidil, 2.2% ketoconazole, and 0.2% biotin, applied nightly. They reported good results without microneedling and prefer the topical form over oral medication.
The conversation discusses preventing hair loss during detransitioning, with suggestions to use finasteride or dutasteride as DHT blockers. The user is also considering rosemary oil and monitoring testosterone levels.
Dutasteride may affect semen parameters but not significantly enough to impact fertility unless baseline fertility is already low. Finasteride and minoxidil are used for hair regrowth, with no side effects reported by one user.
The conversation discusses challenges and tips for applying liquid topical minoxidil twice a day, with users sharing their experiences and methods for managing greasy hair. Many users apply minoxidil once at night, and some combine it with finasteride for better results.
The conversation discusses using a TCA 35% chemical peel on the scalp to potentially improve hair growth by addressing fibrosis and enhancing the effectiveness of topical treatments. The user also mentions trying microneedling and other methods like topical metformin and dutasteride for hair regrowth.
A 100ml bottle of lotion containing Minoxidil 6%, Finasteride 1%, and Retinoic acid 0.01% is estimated to last around 100 days if using 0.5ml daily. The user cannot take oral finasteride due to liver issues.
Breezula's effectiveness may depend on the vehicle used for its application, with concerns about the grey market version's formulation. Phase 3 results are promising, but skepticism remains about the grey market product's authenticity and effectiveness.
A 20-year-old male experiencing hair thinning uses 1mg finasteride and 2.5mg minoxidil daily, and seeks styling advice to hide frontal scalp thinning. Recommendations include using hair powder, mousse, sea salt spray, and matte clay, along with specific styling techniques like blow-drying and using a detangling brush.
The user is experiencing hair regrowth and increased hair thickness after using supplements like biotin, zinc, selenium, and a complex with various natural ingredients, along with topical caffeine. They are considering using topical minoxidil and mesotherapy in the future.
The conversation discusses hair care tips and product recommendations for hair growth, including red light therapy, The Ordinary hair density serum, Nizoral shampoo, and Minoxidil. It also covers nutrition, stress management, and the importance of blood work for addressing hair loss.
Mixing minoxidil and stemoxydine is not recommended due to potential dilution and reduced effectiveness. Applying them separately with a time gap is suggested.
The user is experiencing increased hair shedding after using oral minoxidil and is considering topical dutasteride but is concerned about potential worsening. They are also exploring other topical treatments like latanoprost, caffeine, and melatonin, and seeking advice on application methods without pulling out existing hair.
RU58841 is debated for hair loss treatment, with concerns about safety and effectiveness. Some users prefer premixed solutions despite higher costs, while others report issues with DIY methods and potential health risks.
A user shared their successful hair regrowth journey using 0.5 mg Dutasteride, 2.5 mg oral Minoxidil, and Biotin gummies, after switching from Finasteride due to insomnia. They highlighted the importance of brushing the scalp for blood flow and reported significant progress in four months without side effects.
The user is seeking advice on mixing 5% Minoxidil with 0.025% Tretinoin for hair loss treatment, as they cannot find a suitable product in India and are considering making it themselves. They express concerns about mixing ratios and stability, while others suggest applying them separately or mixing them with other ingredients like finasteride and RU58841.
The conversation discusses using stemoxydine for hair loss, with OP considering using 1.5 ml daily despite the recommended 6 ml. Some users doubt its effectiveness, while others report positive experiences using similar amounts.
The user is using topical minoxidil, topical finasteride, microneedling, and Nizoral shampoo for hair regrowth. Other users suggest the appearance of regrowth might be due to brushing hair differently.
OP experienced side effects from finasteride and is considering trying RU58841 for hair loss, while currently using minoxidil, Stemoxydine, a dermapen, and Nizoral. Another user shared positive results with RU58841, noting no side effects and maintained hair thickness after stopping its use.