enzyme that breaks down proteins in the extracellular matrix
Matrix Metalloproteinase-2 (MMP-2), also known as Gelatinase A, is an enzyme that breaks down proteins in the extracellular matrix, particularly type IV collagen. This process is crucial for tissue remodeling, wound healing, and angiogenesis, but excessive MMP-2 activity can contribute to diseases like cancer and fibrosis by promoting abnormal tissue degradation.