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      community What happened to Pyrilutamide?

      in Technology  1 upvotes 1 year ago
      Pyrilutamide's 0.5% solution showed minimal improvement, while the 1% solution appears more promising but costly. The user is currently using finasteride and oral minoxidil and considering adding Pyrilutamide if effective and affordable.

      community Creatine effects on DHT Experiment

       57 upvotes 2 years ago
      Creatine might increase hair loss due to increased DHT sensitivity, but evidence is mostly anecdotal. The user is using oral minoxidil for hair loss and is cautious about starting creatine.

      community What is something that is treated as common knowledge or consensus in this community but lacks evidence, is missing nuance, or is simply untrue?

      in Chat  4 upvotes 4 months ago
      Common misconceptions about hair loss treatments include the belief that lower doses of finasteride are as effective as higher doses, and that ketoconazole is effective for androgenetic alopecia without scalp issues. Additionally, minoxidil's effects can be seen sooner than commonly thought, and topical dutasteride is effective.

      community Aminexil - does anyone us this?

       5 upvotes 4 years ago
      Aminexil is similar to Minoxidil but less effective and not widely used, with some users reporting minor regrowth. It is not FDA-approved and has been removed from some products, though some people still use it, often in combination with Minoxidil.

      community About Pyrilutamide Phase II US Trial

      in Research/Science  11 upvotes 3 years ago
      The conversation discusses the comparison of Pyrilutamide Phase II US trial results with 1 mg finasteride for hair loss treatment. It mentions that the total hair count increase in the US trial was not as good as the China trial.

      community PP405 Effectiveness in Transplant Area?

       5 upvotes 8 months ago
      Hair transplant recipients are concerned about whether dormant follicles are permanently damaged by incisions, but some believe undamaged follicles could still regrow if a treatment like PP405 is effective. Opinions vary on the impact of transplants on original follicles, with some suggesting treatments like finasteride can help regrow hair.

      community Failed HT or expected result? 4505 grafts, Eugenix, New Delhi.

      in Transplants  36 upvotes 1 year ago
      The hair transplant at Eugenix in New Delhi resulted in poor density and texture, with only about 2,500 grafts surviving out of 4,500. The user is considering holding the clinic accountable and exploring options like shaving, using hair fibers, or seeking another transplant.

      community I want to attempt to use the MPC inhibitor JXL-069

      in Research/Science  14 upvotes 1 year ago
      The conversation discusses skepticism about group buys for hair loss treatments, highlighting issues with unverified chemicals and the risks involved. It suggests stabilizing with dutasteride and minoxidil, and considering a hair transplant instead of experimenting with untested products.

      community CB-03-01 / Breezula Personal Results

       17 upvotes 7 months ago
      The user shared their experience with CB-03-01 (Breezula/Clascoterone) for hair loss, noting reduced shedding and improved hair appearance but experiencing significant sleep disturbances and low energy due to HPA axis suppression. They decided to stop using it due to these side effects and are waiting for GT20029 as an alternative.

      community KX-826 Phase 3 Results Are Out

       121 upvotes 6 months ago
      KX-826 shows promising results for hair growth with fewer side effects, offering an alternative to finasteride and minoxidil. Users discuss combining it with minoxidil, dermarolling, and Nizoral for improved results.

      community Opinion on the recent clascoterone breakthrough?

      in Treatment  3 upvotes 8 months ago
      Clascoterone has shown promising results in increasing hair density without systemic side effects, potentially offering benefits similar to finasteride. There is skepticism due to the lack of published photos despite the market interest.

      community What happens to the excess testosterone after using dut?

      in Finasteride/Dutasteride  23 upvotes 1 year ago
      Using dutasteride or finasteride can increase free testosterone, which may convert to estradiol, potentially causing side effects like increased estrogen levels. Individual responses vary, and some users report changes in cholesterol, hair texture, and side effects like gyno or increased sex drive.

      community Has anyone tried Haircross Hair Growth Serum with Redensyl, Capixyl, and Procapil? Results and experiences?

       1 upvotes 1 year ago
      The conversation discusses experiences with Haircross Hair Growth Serum, which contains Redensyl, Capixyl, Procapil, Anagain, and Baicapil, as an alternative to Minoxidil and Finasteride. Users report mixed results, with some experiencing no regrowth and others noting slight thickening, but concerns about side effects and effectiveness compared to standard treatments remain.

      community Crazy 6 month oral minoxidil and GHK-CU transformation

       266 upvotes 2 months ago
      The user shared a 6-month update on using oral minoxidil and GHK-Cu for hair regrowth, noting significant improvement and increased confidence. Some commenters questioned the authenticity of the transformation, mentioning visible hair fibers, while others discussed the role of DHT blockers and religious perspectives.

      community Switch from fin to dut and its worse

       4 upvotes 1 year ago
      Switching from finasteride to dutasteride can worsen hair loss for some men due to increased testosterone levels. Topical treatments like RU58841 and Pyrilutamide are suggested to counteract these effects, but individual responses vary.

      community I mixed Pyrilutamide with a KB solution

       6 upvotes 4 years ago
      The user mixed Pyrilutamide with a KB solution and noticed some undissolved powder, questioning if more shaking or liquid is needed. They use Pyrilutamide from Anagenic.

      community microneedling efficacy for male pattern baldness?

      in Microneedling  14 upvotes 4 months ago
      Microneedling, when combined with finasteride and topical minoxidil, can enhance hair regrowth for male pattern baldness, especially at the temples. Users report varying success with needle depths between 0.5mm and 1.5mm, with stamps preferred over rollers to minimize scalp damage.

      community So I tried the natural approach and..

      in Chat  2 upvotes 1 year ago
      Natural DHT blockers caused negative side effects like weak erections and depression, while finasteride improved overall well-being and cleared acne. Users shared similar experiences, finding finasteride effective without the adverse effects of natural treatments.

      community Mechanism of action of alfatradiol (17 alpha estradiol)

       5 upvotes 2 years ago
      The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.